In:
Fetal Diagnosis and Therapy, S. Karger AG, Vol. 20, No. 2 ( 2005), p. 86-90
Abstract:
〈 i 〉 Objective: 〈 /i 〉 From analysis of fetal renal artery hemodynamics, we attempted to reveal renal glomerular and tubular function in normal fetuses during pregnancy. 〈 i 〉 Design: 〈 /i 〉 The study included 36 cases of normal fetuses from the 20th to the 40th week of gestation; V 〈 sub 〉 max 〈 /sub 〉 (the systolic peak velocity of main renal artery), V 〈 sub 〉 mean 〈 /sub 〉 (time averages of trace of peak velocity) blood flow were initially measured between 20 and 24 weeks of gestation and every 4 weeks thereafter. The measurement was performed a total of five times in a longitudinal study. In addition, the blood flow waveform was concurrently examined. 〈 i 〉 Results: 〈 /i 〉 The V 〈 sub 〉 max 〈 /sub 〉 was 22.02 ± 0.50 cm/s at 20–24 weeks of gestation. This standard value (100%) was found to increase for each group as follows: 125.2, 149.1, 156.1, and 181.5%. Furthermore, using 20–24 〈 sup 〉 〈 /sup 〉 weeks of gestation as the standard, the V 〈 sub 〉 mean 〈 /sub 〉 increased after the 37th week of gestation: 186.7%, respectively. At 20–24 weeks of gestation, the blood flow wave forms consisted of 43.2% type I (only systolic waveforms), and 56.8% type II (both systolic and diastolic waveforms). Type III waveforms (waveforms that extended beyond the diastolic to the next systolic component) were not recognized. In the 33- to 36-week group, 82.6% of the waveforms were type II, and in the 37- to 40-week group, 76.2% of the waveforms were type III. 〈 i 〉 Conclusions: 〈 /i 〉 The V 〈 sub 〉 max 〈 /sub 〉 and V 〈 sub 〉 mean 〈 /sub 〉 of the renal artery in normal fetuses exhibit a similar rate increase when 20–24 weeks of gestation is compared to 37–40 weeks of gestation. The blood flow waveforms changed as pregnancy progresses; thus, it was inferred that this finding was related to the development of the renal glomerular and renal tubular function.
Type of Medium:
Online Resource
ISSN:
1015-3837
,
1421-9964
Language:
English
Publisher:
S. Karger AG
Publication Date:
2005
detail.hit.zdb_id:
1482292-1
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