In:
Science Translational Medicine, American Association for the Advancement of Science (AAAS), Vol. 14, No. 666 ( 2022-10-12)
Abstract:
There remains a need for easy-to-use ventilators that can be rapidly deployed to provide respiratory support in response to crises or in low-resource environments. Pritchard et al. evaluated miniature in-line ventilators in swine models of acute lung injury. The three-dimensional–printed ventilators were designed to use compressed oxygen and to operate in specific pressure ranges, with three models corresponding to mild, moderate, and severe injury. Testing in swine showed that the devices provided adequate support for acute mild and moderate lung injury but were insufficient for severe injury, resulting in elevated respiratory rate and reduced tidal volume. With further optimization and testing, these ventilators could be a simple yet powerful tool.
Type of Medium:
Online Resource
ISSN:
1946-6234
,
1946-6242
DOI:
10.1126/scitranslmed.abm8351
Language:
English
Publisher:
American Association for the Advancement of Science (AAAS)
Publication Date:
2022
Permalink