GLORIA

GEOMAR Library Ocean Research Information Access

X

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
Material
Publisher
Person/Organisation
Language
Years
FID
Subjects(RVK)
  • 1
    Online Resource
    Online Resource
    Effect of medically lowering intraocular pressure in glaucoma suspects with high myopia (GSHM study): study protocol for a randomized controlled trial
    Springer Science and Business Media LLC ; 2020
    In:  Trials Vol. 21, No. 1 ( 2020-12)
    Details
    In: Trials, Springer Science and Business Media LLC, Vol. 21, No. 1 ( 2020-12)
    Abstract: Currently, whether and when intraocular pressure (IOP)-lowering medication should be used in glaucoma suspects with high myopia (GSHM) remains unknown. Glaucoma suspects are visual field (VF) defects that cannot be explained by myopic macular changes or other retinal and neurologic conditions. Glaucoma progression is defined by VF deterioration. Here we describe the rationale, design, and methodology of a randomized controlled trial (RCT) designed to evaluate the effects of medically lowering IOP in GSHM (GSHM study). Methods The GSHM study is an open-label, single-center, RCT for GSHM. Overall, 264 newly diagnosed participants, aged 35 to 65 years, will be recruited at the Zhongshan Ophthalmic Center, Sun Yat-sen University, between 2020 and 2021. Participants will be randomly divided into two arms at a 1:1 ratio. Participants in the intervention arm will receive IOP-lowering medication, while participants in the control arm will be followed up without treatment for 36 months or until they reach the end point. Only one eye per participant will be eligible for the study. If both eyes are eligible, the eye with the worse VF will be recruited. The primary outcome is the incidence of glaucoma suspect progression by VF testing over 36 months. The secondary outcomes include the incidence of changes in the optic nerve head morphology including the retinal nerve fiber layer, and retinal ganglion cell-inner plexiform layer loss, progression of myopic maculopathy, visual function loss, and change in the quality of life. Statistical analyses will include baseline characteristics comparison between the intervention and control groups using a two-sample t -test and Wilcoxon rank sum test; generalized linear models with Poisson regression for the primary outcome; Kaplan-Meier curve and log-rank test for the incidence of the secondary outcome; and longitudinal analyses to assess trends in outcomes across time. Discussion To the best of our knowledge, the GSHM study is the first RCT to investigate the impact of medically lowering IOP in GSHM. The results will have implications for the clinical management of GSHM. Trial registration ClinicalTrials.gov NCT04296916. Registered on 4 March 2020
    Type of Medium: Online Resource
    ISSN: 1745-6215
    URL: Article
    DOI: 10.1186/s13063-020-04748-7
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2020
    detail.hit.zdb_id: 2040523-6
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 2
    Online Resource
    Online Resource
    Efficacy of low‐dose versus high‐dose simethicone with polyethylene glycol for bowel preparation: A prospective randomized controlled trial
    Wiley ; 2020
    In:  Journal of Gastroenterology and Hepatology Vol. 35, No. 9 ( 2020-09), p. 1488-1494
    Details
    In: Journal of Gastroenterology and Hepatology, Wiley, Vol. 35, No. 9 ( 2020-09), p. 1488-1494
    Abstract: Additional simethicone (SIM) can improve adequate bowel preparation and adenoma detection rate (ADR). However, there is no consensus on the optimal dose of SIM. In this study, we compared the adequate bowel preparation rate with supplementation of split‐dose 2 L polyethylene glycol (PEG) with low‐dose SIM (200 mg) versus high‐dose SIM (1200 mg). Methods This was a prospective, randomized, observer‐blinded trial involving consecutive subjects undergoing colonoscopy. The primary outcome was adequate bowel preparation as assessed by Boston Bowel Preparation Scale (BBPS) score. Results Four hundred subjects were randomly allocated to low‐dose SIM or high‐dose SIM group. Baseline characteristics were comparable in the two groups ( P   〉  0.05). No significant between‐group differences were observed with respect to total bubble scale (BS) (8.49 ± 1.00 vs 8.39 ± 1.10, P  = 0.07), total BBPS score (8.70 ± 0.81 vs 8.29 ± 1.18, P  = 0.98), ADR (33.68% vs 31.79%, P  = 0.69) or withdrawal time (13 [range, 10–16] min vs 13 [10–15] min, P  = 0.96). The intubation time in low‐dose SIM group was significantly shorter than that in high‐dose SIM group (8 (4–16) min vs 10 [6–17] min, P  = 0.04). In addition, BS scores as well as diminutive ADR in right colon were superior in the low‐dose SIM group (2.68 ± 0.59 vs 2.52 ± 0.73, P  = 0.03 and 54.29% vs 30.30%, P  = 0.046, respectively). Conclusion Addition of low‐dose SIM to split‐dose 2 L PEG was as effective as addition of high‐dose SIM with respect to adequate bowel preparation, ADR and patient tolerance. However, low‐dose SIM was superior with respect to intubation time, right colon BS scores, right colon diminutive ADR and cost savings.
    Type of Medium: Online Resource
    ISSN: 0815-9319 , 1440-1746
    URL: Issue
    URL: Article
    DOI: 10.1111/jgh.v35.9
    DOI: 10.1111/jgh.15022
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2006782-3
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    BACK ANALYSIS AND STABILITY PREDICTION OF SURROUNDING ROCK DURING EXCAVATION OF THE SHUANGJIANGKOU UNDERGROUND POWERHOUSE
    Vilnius Gediminas Technical University ; 2024
    In:  JOURNAL OF CIVIL ENGINEERING AND MANAGEMENT Vol. 30, No. 3 ( 2024-04-04), p. 264-278
    Details
    In: JOURNAL OF CIVIL ENGINEERING AND MANAGEMENT, Vilnius Gediminas Technical University, Vol. 30, No. 3 ( 2024-04-04), p. 264-278
    Abstract: The underground powerhouse of the Shuangjiangkou hydropower station is one of the largest caverns under construction in China, and its stability during construction is crucial for safe construction. To study the stability of the surrounding rock during excavation, the displacement and stress of the surrounding rock were monitored by multi-point displacement meters and bolt stress meters. Based on the monitoring data, the elastic modulus, Poisson’s ratio, friction angle, and cohesion of surrounding rock were inversely analyzed by the PSO-BP algorithm. Then, the back-analyzed parameters were used to simulate the subsequent excavations and predict the stability of surrounding rock during the following construction. The analysis results show that the surrounding rocks were generally stable during the initial four stages of excavation, and the main factors affecting their stability were blasts and unfavorable geological structures, including the lamprophyre vein and the F1 fault. These unfavorable geological structures also significantly decrease the mechanical parameters of surrounding rock as demonstrated by back analysis, and the stability prediction results show that the omnibus bar cave and the tailrace tunnel were at the greatest risk of instability during the subsequent excavations. This study provides a practical analysis for engineering excavation of the underground caverns.
    Type of Medium: Online Resource
    ISSN: 1392-3730 , 1822-3605
    URL: Article
    DOI: 10.3846/jcem.2024.20778
    Language: Unknown
    Publisher: Vilnius Gediminas Technical University
    Publication Date: 2024
    detail.hit.zdb_id: 2571620-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    The efficacy and safety of underwater endoscopic mucosal resection for ≥10-mm colorectal polyps: systematic review and meta-analysis
    Georg Thieme Verlag KG ; 2021
    In:  Endoscopy Vol. 53, No. 06 ( 2021-06), p. 636-646
    Details
    In: Endoscopy, Georg Thieme Verlag KG, Vol. 53, No. 06 ( 2021-06), p. 636-646
    Abstract: Background Underwater endoscopic mucosal resection (UEMR) is a promising strategy for nonpedunculated colorectal polyp removal. However, the efficacy and safety of the technique for the treatment of ≥ 10-mm colorectal polyps remain unclear. We aimed to comprehensively assess the efficacy and safety of UEMR for polyps sized 10–19 mm and ≥ 20 mm. Methods PubMed, EMBASE, and the Cochrane Library databases were searched for relevant articles from January 2012 to November 2019. Primary outcomes were the rates of adverse events and residual polyps. Secondary outcomes were the complete resection, en bloc resection, and R0 resection rates. Results 18 articles including 1142 polyps from 1093 patients met our inclusion criteria. The overall adverse event and residual polyp rates were slightly lower for UEMR when removing colorectal polyps of 10–19 mm vs. ≥ 20 mm (3.5 % vs. 4.3 % and 1.2 % vs. 2.6 %, respectively). The UEMR-related complete resection rate was slightly higher for colorectal polyps of 10–19 mm vs. ≥ 20 mm (97.9 % vs. 92.0 %). However, the en bloc and R0 resection rates were dramatically higher for UEMR removal of polyps of 10–19 mm vs. ≥ 20 mm (83.4 % vs. 36.1 % and 73.0 % vs. 40.0 %, respectively). In addition, univariate meta-regression revealed that polyp size was an independent predictor for complete resection rate (P = 0.03) and en bloc resection (P = 0.01). Conclusions UEMR was an effective and safe technique for the removal of ≥ 10-mm nonpedunculated colorectal polyps. However, UEMR exhibited low en bloc and R0 resection rates for the treatment of ≥ 20-mm polyps.
    Type of Medium: Online Resource
    ISSN: 0013-726X , 1438-8812
    URL: Article
    DOI: 10.1055/a-1234-8918
    RVK:
    XA 41100
    RVK:
    YC 4905
    Language: English
    Publisher: Georg Thieme Verlag KG
    Publication Date: 2021
    detail.hit.zdb_id: 2026213-9
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 5
    Online Resource
    Online Resource
    Insight into the transcriptional regulation of Msn2 required for conidiation, multi-stress responses and virulence of two entomopathogenic fungi
    Elsevier BV ; 2013
    In:  Fungal Genetics and Biology Vol. 54 ( 2013-05), p. 42-51
    Details
    In: Fungal Genetics and Biology, Elsevier BV, Vol. 54 ( 2013-05), p. 42-51
    Type of Medium: Online Resource
    ISSN: 1087-1845
    URL: Article
    DOI: 10.1016/j.fgb.2013.02.008
    RVK:
    WA 15000
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2013
    detail.hit.zdb_id: 1467659-X
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 6
    Online Resource
    Online Resource
    Glycine feeding improves pristinamycin production during fermentation including resin for in situ separation
    Springer Science and Business Media LLC ; 2012
    In:  Bioprocess and Biosystems Engineering Vol. 35, No. 4 ( 2012-5), p. 513-517
    Details
    In: Bioprocess and Biosystems Engineering, Springer Science and Business Media LLC, Vol. 35, No. 4 ( 2012-5), p. 513-517
    Type of Medium: Online Resource
    ISSN: 1615-7591 , 1615-7605
    URL: Article
    DOI: 10.1007/s00449-011-0624-x
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2012
    detail.hit.zdb_id: 1476357-6
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 7
    Online Resource
    Online Resource
    Study on TiO〈sub〉2〈/sub〉 Light-Induced Amphiphilicity on the Erased Plate
    Trans Tech Publications, Ltd. ; 2011
    In:  Advanced Materials Research Vol. 380 ( 2011-11), p. 344-347
    Details
    In: Advanced Materials Research, Trans Tech Publications, Ltd., Vol. 380 ( 2011-11), p. 344-347
    Abstract: Using Sol - gel prepared SiO 2 and TiO 2 thin film and coating on the glass substrate, this paper studied TiO 2 thin films as a new type of printed material with the illumination time and the infiltration of the relationship between light intensity and illumination time on the water-based ink on film surface adsorption. The results show that: TiO 2 thin film by ultraviolet irradiation, its hydrophobic property drastically reduced, and showed super hydrophilic properties and water contact angle down to 5°or less. Thesis results show that: TiO 2 thin film with light-induced amphiphilicity expected as a new type of environmentally friendly reusable printing plate.
    Type of Medium: Online Resource
    ISSN: 1662-8985
    URL: Issue
    URL: Article
    DOI: 10.4028/www.scientific.net/AMR.380
    DOI: 10.4028/www.scientific.net/AMR.380.344
    Language: Unknown
    Publisher: Trans Tech Publications, Ltd.
    Publication Date: 2011
    detail.hit.zdb_id: 2265002-7
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 8
    Online Resource
    Online Resource
    Unveiling equal importance of two 14‐3‐3 proteins for morphogenesis, conidiation, stress tolerance and virulence of an insect pathogen
    Wiley ; 2015
    In:  Environmental Microbiology Vol. 17, No. 4 ( 2015-04), p. 1444-1462
    Details
    In: Environmental Microbiology, Wiley, Vol. 17, No. 4 ( 2015-04), p. 1444-1462
    Abstract: Two conserved 14‐3‐3 proteins orthologous to S accharomyces cerevisiae   Bmh 1/2 are poorly understood in filamentous fungi. Here we show that Bmh 1 and Bmh 2 contribute equally to the fundamental biology and physiology of B eauveria bassiana by targeting many sets of proteins/enzymes. Single Bmh deletion caused similar upregulation of another. Excellent knockdown (∼91%) expressions of Bmh 1 in Δ Bmh 2 and Bmh 2 in Δ Bmh 1 resulted in equally more severe multiphenotypic defects than the single deletions, including G 2 / M transition, blastospore size, carbon/nitrogen utilization, conidiation, germination and conidial tolerances to high osmolarity, oxidation, cell wall stress, high temperature and UV ‐ B irradiation. All the deletion and deletion/knockdown mutants showed similar defects in blastospore yield and density, hyphal septation and cell size, hyphal responses to most chemical stresses and virulence. All the defects were evident with altered transcripts of phenotype‐related genes and well restored by each Bmh complementation. Our Bmh 1 ‐ and Bmh 2 ‐specific transcriptomes generated under osmotic and oxidative stresses revealed up to 6% genes differentially expressed by at least twofold in the fungal genome. Many of those were greatly depressed or co‐depressed in Δ Bmh 1 and Δ Bmh 2 . Our findings provide a thorough insight into the functions and complementary effects of the two 14‐3‐3 proteins in the filamentous entomopathogen.
    Type of Medium: Online Resource
    ISSN: 1462-2912 , 1462-2920
    URL: Issue
    URL: Article
    DOI: 10.1111/emi.2015.17.issue-4
    DOI: 10.1111/1462-2920.12634
    Language: English
    Publisher: Wiley
    Publication Date: 2015
    detail.hit.zdb_id: 2020213-1
    SSG: 12
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 9
    Online Resource
    Online Resource
    Study on UV-Curable Polyester Acrylate/SiO〈sub〉2〈/sub〉 Nanocomposite Resin
    Trans Tech Publications, Ltd. ; 2012
    In:  Applied Mechanics and Materials Vol. 151 ( 2012-1), p. 368-372
    Details
    In: Applied Mechanics and Materials, Trans Tech Publications, Ltd., Vol. 151 ( 2012-1), p. 368-372
    Abstract: Using the hydrolysis reaction of TEOS and ethanol to prepare nano-SiO 2 sol, and grafting with silane coupling agent WD-20 to introduce double bonds to make a surface modification, the nano-SiO 2 sol mixed with the light-cured resin PEA, reactive diluents TPGDA and photoinitiators 1171 under ultrasonicto after dried concentration in vacuum oven, then the composite resin gotten was characterized through FTIR, TGA, UV-Vis and particle size analysis. The results showed as follows: the light-cured resin modified by nano-SiO 2 with WD-20 was better in dispersion and stability, and durability, abrasion resistance and other performances of the coating improved significantly which broadened the application range of light-cured resin.
    Type of Medium: Online Resource
    ISSN: 1662-7482
    URL: Issue
    URL: Article
    DOI: 10.4028/www.scientific.net/AMM.151
    DOI: 10.4028/www.scientific.net/AMM.151.368
    Language: Unknown
    Publisher: Trans Tech Publications, Ltd.
    Publication Date: 2012
    detail.hit.zdb_id: 2251882-4
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 10
    Online Resource
    Online Resource
    Influence of Ink-Jet Paper Surface Characteristics on Color Reproduction
    Trans Tech Publications, Ltd. ; 2012
    In:  Applied Mechanics and Materials Vol. 151 ( 2012-1), p. 373-377
    Details
    In: Applied Mechanics and Materials, Trans Tech Publications, Ltd., Vol. 151 ( 2012-1), p. 373-377
    Abstract: With the rapid development of color science, especially the ink-jet printing, the evaluation of the color copy effectiveness become one of the most important evaluation parameters in the ink-jet printing. Meanwhile, it makes the evaluation of the effectiveness of color reproduction become more and more quantitative. This paper selects four ink-jet printing papers with different types and physical properties, according to measurement and analysis of the whiteness, gloss, roughness, absorption and other performance parameters of the papers, it shows the effect from the various performance parameters of ink-jet printing paper to color reproduction. At the same time, the study of this paper offers a certain practical guidance to the selection of ink-jet printing paper as well as the improvement of replication precision of ink-jet printing.
    Type of Medium: Online Resource
    ISSN: 1662-7482
    URL: Issue
    URL: Article
    DOI: 10.4028/www.scientific.net/AMM.151
    DOI: 10.4028/www.scientific.net/AMM.151.373
    Language: Unknown
    Publisher: Trans Tech Publications, Ltd.
    Publication Date: 2012
    detail.hit.zdb_id: 2251882-4
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...