In:
ChemBioChem, Wiley, Vol. 5, No. 11 ( 2004-11-05), p. 1567-1570
Abstract:
The glycosyltransferase gene lanGT3 , involved in the biosynthesis of the angucyclic antibiotic landomycin A, has been characterised by targeted gene deletion. A lanGT3 mutant was shown to produce landomycin E, which consists of a trisaccharide side chain attached to the polyketide moiety. Expression of lanGT3 in the mutant restored landomycin A production. Our results indicate that LanGT3 is responsible for the transfer of the fourth sugar during landomycin A biosynthesis.
Type of Medium:
Online Resource
ISSN:
1439-4227
,
1439-7633
DOI:
10.1002/cbic.200400123
Language:
English
Publisher:
Wiley
Publication Date:
2004
detail.hit.zdb_id:
2020469-3
SSG:
12
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