In:
International Journal of Gynecology & Obstetrics, Wiley, Vol. 15, No. 6 ( 1978-11), p. 550-553
Abstract:
Two cases of gonadal dysgenesis in phenotypic females associated with different chromosomal patterns are discussed. Both patients presented with primary amenorrhea and were characterized by tall stature and underdeveloped secondary sex characteristics and external and internal reproductive organs. The karyotype of the first patient was 46,XX with a satellite on chromosome 17. The second patient had a normal female chromosome composition (46,XX) with a past history of mumps. Laparoscopic bilateral gonadal biopsies in both patients revealed fibrous tissue without any primordial follicles. This report emphasizes the pathogenesis, clinical significance, diagnosis and management of gonadal dysgenesis.
Type of Medium:
Online Resource
ISSN:
0020-7292
,
1879-3479
DOI:
10.1002/ijgo.1977.15.issue-6
DOI:
10.1002/j.1879-3479.1977.tb00754.x
Language:
English
Publisher:
Wiley
Publication Date:
1978
detail.hit.zdb_id:
1500480-6
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