In:
British Journal of Hospital Medicine, Mark Allen Group, Vol. 80, No. 8 ( 2019-08-02), p. 466-471
Abstract:
Obesity is a major and growing global health problem. It is associated with increased mortality as a result of an increasing number of complications, including type 2 diabetes, dyslipidaemia, hypertension, non-alcoholic hepatic steatosis, cardiovascular disease, sleep apnoea, gallbladder disease, obesity-related renal disease, increased risk of falls and injuries, and mental health problems as well as increased risk of certain malignancies. This article discusses the metabolic derangements associated with obesity. These include insulin resistance, dysglycaemia, low and dysfunctional high-density lipoprotein, formation of small dense and oxidised low-density lipoprotein, and high circulating levels of free fatty acids. This article reviews the aetiology of these derangements and their relationship to cardiovascular disease, and discusses the concept of metabolic health.
Type of Medium:
Online Resource
ISSN:
1750-8460
,
1759-7390
DOI:
10.12968/hmed.2019.80.8.466
Language:
English
Publisher:
Mark Allen Group
Publication Date:
2019
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