In:
Chemistry – An Asian Journal, Wiley, Vol. 12, No. 15 ( 2017-08-04), p. 1865-1868
Abstract:
A facile synthesis of 2‐amino‐1,3‐oxazoles via Cu I ‐catalyzed oxidative cyclization of enamines and N , N ‐dialkyl formamides has been developed. The reaction proceeds through an oxidative C−N bond formation, followed by an intramolecular C(sp 2 )−H bond functionalization/C−O cyclization in one pot. This protocol provides direct access to useful 2‐amino‐1,3‐oxazoles and features protecting‐group‐free nitrogen sources, readily available starting materials, a broad substrate scope and mild reaction conditions.
Type of Medium:
Online Resource
ISSN:
1861-4728
,
1861-471X
DOI:
10.1002/asia.201700503
Language:
English
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
2233006-9
Permalink