In:
N.N. Priorov Journal of Traumatology and Orthopedics, ECO-Vector LLC, Vol. 17, No. 3 ( 2010-09-15), p. 47-51
Abstract:
Osteoprotective effect of enalapril and losartan was studied using experimental model of osteoporosis and osteoporotic fractures (222 female Wistar rats). It was detected that in rats after ovariectomy endothelial vascular dysfunction of microcirculation in bone tissue bed developed. Those changes caused osteoporosis and delayed experimental fracture healing. Enalapril and losartan prevented the decrease of microcirculation level in bone tissue that promoted slowing-down of osseous trabecula thinning, prevented microfractures and increased the healing rate of experimental fractures.
Type of Medium:
Online Resource
ISSN:
2658-6738
,
0869-8678
DOI:
10.17816/vto201017347-51
Language:
Unknown
Publisher:
ECO-Vector LLC
Publication Date:
2010
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