In:
Annals of the New York Academy of Sciences, Wiley, Vol. 936, No. 1 ( 2001-06), p. 522-525
Abstract:
A bstract : Fibrinogen storage in liver cells can occur under three different morphological inclusions. Type I contain all three fibrinogen chains (Aα, Bβ, and γ) as well as D and E fragments, whereas type II and III lack Bβ as well as D and E fragments. Patients with type I inclusions carry a point mutation (γ284 Gly‐Arg). The mutation is not present in patients with type II and III inclusions. These results appear to suggest that the three various phenotypic expressions (i.e., morphological variants) reflect different genetical abnormalities of fibrinogen.
Type of Medium:
Online Resource
ISSN:
0077-8923
,
1749-6632
DOI:
10.1111/nyas.2001.936.issue-1
DOI:
10.1111/j.1749-6632.2001.tb03538.x
Language:
English
Publisher:
Wiley
Publication Date:
2001
detail.hit.zdb_id:
2834079-6
detail.hit.zdb_id:
211003-9
detail.hit.zdb_id:
2071584-5
SSG:
11
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