In:
American Journal of Physiology-Endocrinology and Metabolism, American Physiological Society, Vol. 280, No. 2 ( 2001-02-01), p. E340-E348
Abstract:
To evaluate the importance of protein digestion rate on protein deposition, we characterized leucine kinetics after ingestion of “protein” meals of identical amino acid composition and nitrogen contents but of different digestion rates. Four groups of five or six young men received anl-[1- 13 C]leucine infusion and one of the following 30-g protein meals: a single meal of slowly digested casein (CAS), a single meal of free amino acid mimicking casein composition (AA), a single meal of rapidly digested whey proteins (WP), or repeated meals of whey proteins (RPT-WP) mimicking slow digestion rate. Comparisons were made between “fast” (AA, WP) and “slow” (CAS, RPT-WP) meals of identical amino acid composition (AA vs. CAS, and WP vs. RPT-WP). The fast meals induced a strong, rapid, and transient increase of aminoacidemia, leucine flux, and oxidation. After slow meals, these parameters increased moderately but durably. Postprandial leucine balance over 7 h was higher after the slow than after the fast meals (CAS: 38 ± 13 vs. AA: −12 ± 11, P 〈 0.01; RPT-WP: 87 ± 25 vs. WP: 6 ± 19 μmol/kg, P 〈 0.05). Protein digestion rate is an independent factor modulating postprandial protein deposition.
Type of Medium:
Online Resource
ISSN:
0193-1849
,
1522-1555
DOI:
10.1152/ajpendo.2001.280.2.E340
Language:
English
Publisher:
American Physiological Society
Publication Date:
2001
detail.hit.zdb_id:
1477331-4
SSG:
12
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