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  • 1
    In: Biodiversity Data Journal, Pensoft Publishers, Vol. 7 ( 2019-09-27)
    Abstract: The 150 grassland plots were located in three study regions in Germany, 50 in each region. The dataset describes the yearly grassland management for each grassland plot using 116 variables. General information includes plot identifier, study region and survey year. Additionally, grassland plot characteristics describe the presence and starting year of drainage and whether arable farming had taken place 25 years before our assessment, i.e. between 1981 and 2006. In each year, the size of the management unit is given which, in some cases, changed slightly across years. Mowing, grazing and fertilisation were systematically surveyed: Mowing is characterised by mowing frequency (i.e. number of cuts per year), dates of cutting and different technical variables, such as type of machine used or usage of conditioner. For grazing , the livestock species and age (e.g. cattle, horse, sheep), the number of animals, stocking density per hectare and total duration of grazing were recorded. As a derived variable, the mean grazing intensity was then calculated by multiplying the livestock units with the duration of grazing per hectare [LSU days/ha]. Different grazing periods during a year, partly involving different herds, were summed up to an annual grazing intensity for each grassland. For fertilisation , information on the type and amount of different types of fertilisers was recorded separately for mineral and organic fertilisers, such as solid farmland manure, slurry and mash from a bioethanol factory. Our fertilisation measures neglect dung dropped by livestock during grazing. For each type of fertiliser, we calculated its total nitrogen content, derived from chemical analyses by the producer or agricultural guidelines (Table 3). All three management types, mowing, fertilisation and grazing, were used to calculate a combined land use intensity index (LUI) which is frequently used to define a measure for the land use intensity. Here, fertilisation is expressed as total nitrogen per hectare [kg N/ha], but does not consider potassium and phosphorus. Information on additional management practices in grasslands was also recorded including levelling, to tear-up matted grass covers, rolling, to remove surface irregularities, seed addition, to close gaps in the sward. Investigating the relationship between human land use and biodiversity is important to understand if and how humans affect it through the way they manage the land and to develop sustainable land use strategies. Quantifying land use (the ‘X’ in such graphs) can be difficult as humans manage land using a multitude of actions, all of which may affect biodiversity, yet most studies use rather simple measures of land use, for example, by creating land use categories such as conventional vs. organic agriculture. Here, we provide detailed data on grassland management to allow for detailed analyses and the development of land use theory. The raw data have already been used for & gt; 100 papers on the effect of management on biodiversity (e.g. Manning et al. 2015).
    Type of Medium: Online Resource
    ISSN: 1314-2828 , 1314-2836
    Language: Unknown
    Publisher: Pensoft Publishers
    Publication Date: 2019
    detail.hit.zdb_id: 2736709-5
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  • 2
    In: Frontiers in Cardiovascular Medicine, Frontiers Media SA, Vol. 9 ( 2022-4-19)
    Abstract: Although disease etiologies differ, heart failure patients with preserved and reduced ejection fraction (HFpEF and HFrEF, respectively) both present with clinical symptoms when under stress and impaired exercise capacity. The extent to which the adaptation of heart rate (HR), stroke volume (SV), and cardiac output (CO) under stress conditions is altered can be quantified by stress testing in conjunction with imaging methods and may help to detect the diminishment in a patient’s condition early. The aim of this meta-analysis was to quantify hemodynamic changes during physiological and pharmacological stress testing in patients with HF. A systematic literature search (PROSPERO 2020:CRD42020161212) in MEDLINE was conducted to assess hemodynamic changes under dynamic and pharmacological stress testing at different stress intensities in HFpEF and HFrEF patients. Pooled mean changes were estimated using a random effects model. Altogether, 140 study arms with 7,248 exercise tests were analyzed. High-intensity dynamic stress testing represented 73% of these data (70 study arms with 5,318 exercise tests), where: HR increased by 45.69 bpm (95% CI 44.51–46.88; I 2 = 98.4%), SV by 13.49 ml (95% CI 6.87–20.10; I 2 = 68.5%), and CO by 3.41 L/min (95% CI 2.86–3.95; I 2 = 86.3%). No significant differences between HFrEF and HFpEF groups were found. Despite the limited availability of comparative studies, these reference values can help to estimate the expected hemodynamic responses in patients with HF. No differences in chronotropic reactions, changes in SV, or CO were found between HFrEF and HFpEF. When compared to healthy individuals, exercise tolerance, as well as associated HR and CO changes under moderate-high dynamic stress, was substantially impaired in both HF groups. This may contribute to a better disease understanding, future study planning, and patient-specific predictive models. Systematic Review Registration [ https://www.crd.york.ac.uk/prospero/ ], identifier [CRD42020161212] .
    Type of Medium: Online Resource
    ISSN: 2297-055X
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2022
    detail.hit.zdb_id: 2781496-8
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  • 3
    In: BMJ Open, BMJ, Vol. 13, No. 3 ( 2023-03), p. e067311-
    Abstract: Few studies and almost exclusively from the USA have recently investigated mobile phone and computer use among users of psychiatric services, which is of high relevance regarding the increasing development of digital health applications and services. Objective, design and setting In a cross-sectional patient survey, we examined (a) rates and purposes of mobile phone, computer, internet and social media use, and (b) the role of social and clinical predictors on rates of utilisation among psychiatric inpatients in Berlin, Germany. Participants and results Descriptive analyses showed that among 496 participants, 84.9% owned a mobile phone and 59.3% a smartphone. Among 493 participants, 68.4% used a computer regularly. Multivariate logistic regression models revealed being homeless, diagnosis of a psychotic illness, being of older age and a lower level of education to be significant predictors for not owning a mobile phone, not using a computer regularly or having a social media account, respectively. Conclusions Users of psychiatric services may have access to mobile phones and computers, although rates are lower than in the general population. However, key barriers that need to be addressed regarding the development of and engagement with digital health interventions are factors of social exclusion like marginalised housing as well as clinical aspects like psychotic illness.
    Type of Medium: Online Resource
    ISSN: 2044-6055 , 2044-6055
    Language: English
    Publisher: BMJ
    Publication Date: 2023
    detail.hit.zdb_id: 2599832-8
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  • 4
    In: Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, Springer Science and Business Media LLC, Vol. 66, No. 2 ( 2023-02), p. 136-142
    Abstract: The COVID 19 crisis has highlighted the key role of the public health service (PHS), with its approximately 375 municipal health offices involved in the pandemic response. Here, in addition to a lack of human resources, the insufficient digital maturity of many public health departments posed a hurdle to effective and scalable infection reporting and contact tracing. In this article, we present the maturity model (MM) for the digitization of health offices, the development of which took place between January 2021 and February 2022 and was funded by the German Federal Ministry of Health. It has been applied since the beginning of 2022 with the aim of strengthening the digitization of the PHS. The MM aims to guide public health departments step by step to increase their digital maturity to be prepared for future challenges. The MM was developed and evaluated based on qualitative interviews with employees of public health departments and other experts in the public health sector as well as in workshops and with a quantitative survey. The MM allows the measurement of digital maturity in eight dimensions, each of which is subdivided into two to five subdimensions. Within the subdimensions a classification is made on five different maturity levels. Currently, in addition to recording the digital maturity of individual health departments, the MM also serves as a management tool for planning digitization projects. The aim is to use the MM as a basis for promoting targeted communication between the health departments to exchange best practices for the different dimensions.
    Type of Medium: Online Resource
    ISSN: 1436-9990 , 1437-1588
    Language: German
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 1470303-8
    SSG: 20,1
    SSG: 8,1
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  • 5
    In: Veterinary Pathology, SAGE Publications
    Abstract: Borna disease is a progressive meningoencephalitis caused by spillover of the Borna disease virus 1 (BoDV-1) to horses and sheep and has gained attention due to its zoonotic potential. New World camelids are also highly susceptible to the disease; however, a comprehensive description of the pathological lesions and viral distribution is lacking for these hosts. Here, the authors describe the distribution and severity of inflammatory lesions in alpacas ( n = 6) naturally affected by this disease in comparison to horses ( n = 8) as known spillover hosts. In addition, the tissue and cellular distribution of the BoDV-1 was determined via immunohistochemistry and immunofluorescence. A predominant lymphocytic meningoencephalitis was diagnosed in all animals with differences regarding the severity of lesions. Alpacas and horses with a shorter disease duration showed more prominent lesions in the cerebrum and at the transition of the nervous to the glandular part of the pituitary gland, as compared to animals with longer disease progression. In both species, viral antigen was almost exclusively restricted to cells of the central and peripheral nervous systems, with the notable exception of virus-infected glandular cells of the Pars intermedia of the pituitary gland. Alpacas likely represent dead-end hosts similar to horses and other spillover hosts of BoDV-1.
    Type of Medium: Online Resource
    ISSN: 0300-9858 , 1544-2217
    Language: English
    Publisher: SAGE Publications
    Publication Date: 2023
    detail.hit.zdb_id: 2106608-5
    SSG: 22
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  • 6
    Online Resource
    Online Resource
    JMIR Publications Inc. ; 2021
    In:  Journal of Medical Internet Research Vol. 23, No. 11 ( 2021-11-29), p. e26522-
    In: Journal of Medical Internet Research, JMIR Publications Inc., Vol. 23, No. 11 ( 2021-11-29), p. e26522-
    Abstract: Artificial intelligence (AI) holds the promise of supporting nurses’ clinical decision-making in complex care situations or conducting tasks that are remote from direct patient interaction, such as documentation processes. There has been an increase in the research and development of AI applications for nursing care, but there is a persistent lack of an extensive overview covering the evidence base for promising application scenarios. Objective This study synthesizes literature on application scenarios for AI in nursing care settings as well as highlights adjacent aspects in the ethical, legal, and social discourse surrounding the application of AI in nursing care. Methods Following a rapid review design, PubMed, CINAHL, Association for Computing Machinery Digital Library, Institute of Electrical and Electronics Engineers Xplore, Digital Bibliography & Library Project, and Association for Information Systems Library, as well as the libraries of leading AI conferences, were searched in June 2020. Publications of original quantitative and qualitative research, systematic reviews, discussion papers, and essays on the ethical, legal, and social implications published in English were included. Eligible studies were analyzed on the basis of predetermined selection criteria. Results The titles and abstracts of 7016 publications and 704 full texts were screened, and 292 publications were included. Hospitals were the most prominent study setting, followed by independent living at home; fewer application scenarios were identified for nursing homes or home care. Most studies used machine learning algorithms, whereas expert or hybrid systems were entailed in less than every 10th publication. The application context of focusing on image and signal processing with tracking, monitoring, or the classification of activity and health followed by care coordination and communication, as well as fall detection, was the main purpose of AI applications. Few studies have reported the effects of AI applications on clinical or organizational outcomes, lacking particularly in data gathered outside laboratory conditions. In addition to technological requirements, the reporting and inclusion of certain requirements capture more overarching topics, such as data privacy, safety, and technology acceptance. Ethical, legal, and social implications reflect the discourse on technology use in health care but have mostly not been discussed in meaningful and potentially encompassing detail. Conclusions The results highlight the potential for the application of AI systems in different nursing care settings. Considering the lack of findings on the effectiveness and application of AI systems in real-world scenarios, future research should reflect on a more nursing care–specific perspective toward objectives, outcomes, and benefits. We identify that, crucially, an advancement in technological-societal discourse that surrounds the ethical and legal implications of AI applications in nursing care is a necessary next step. Further, we outline the need for greater participation among all of the stakeholders involved.
    Type of Medium: Online Resource
    ISSN: 1438-8871
    Language: English
    Publisher: JMIR Publications Inc.
    Publication Date: 2021
    detail.hit.zdb_id: 2028830-X
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  • 7
    Online Resource
    Online Resource
    Elsevier BV ; 2021
    In:  Social Science & Medicine Vol. 289 ( 2021-11), p. 114420-
    In: Social Science & Medicine, Elsevier BV, Vol. 289 ( 2021-11), p. 114420-
    Type of Medium: Online Resource
    ISSN: 0277-9536
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2021
    detail.hit.zdb_id: 1500748-0
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  • 8
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2021
    In:  Electronic Markets Vol. 31, No. 4 ( 2021-12), p. 811-828
    In: Electronic Markets, Springer Science and Business Media LLC, Vol. 31, No. 4 ( 2021-12), p. 811-828
    Abstract: Multi-sided platforms in healthcare often focus their business model on standardizing care for wide-spread, chronic diseases. However, there is a lack of knowledge surrounding platform business models enabling individualized care coordination for patients with rare diseases. This paper analyses the development of a complex platform business model addressing Amyotrophic Lateral Sclerosis, a severe neurological disease that requires the coordination of a diverse network of medical specialists, care, and equipment providers. A longitudinal case study examines the platform’s development, focusing subsequently on qualitative and efficient care coordination, care research, and active and direct involvement of patients, as well as establishing two business models, namely, care coordination and care research. We reconstruct how these complex platform business models were configured to improve patient care and care research, thereby creating immediate value for patients and insights for long-term care improvements. The ongoing platform development carefully balances value generation for diverse stakeholders and economic sustainability.
    Type of Medium: Online Resource
    ISSN: 1019-6781 , 1422-8890
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2017342-8
    detail.hit.zdb_id: 1309988-7
    SSG: 3,2
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  • 9
    Online Resource
    Online Resource
    Springer Science and Business Media LLC ; 2022
    In:  Business & Information Systems Engineering Vol. 64, No. 4 ( 2022-08), p. 543-545
    In: Business & Information Systems Engineering, Springer Science and Business Media LLC, Vol. 64, No. 4 ( 2022-08), p. 543-545
    Type of Medium: Online Resource
    ISSN: 2363-7005 , 1867-0202
    RVK:
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
    detail.hit.zdb_id: 2478345-6
    SSG: 3,2
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  • 10
    In: Academy of Management Proceedings, Academy of Management, Vol. 2023, No. 1 ( 2023-08)
    Type of Medium: Online Resource
    ISSN: 0065-0668 , 2151-6561
    Language: English
    Publisher: Academy of Management
    Publication Date: 2023
    detail.hit.zdb_id: 2069299-7
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