In:
Clinical and Experimental Pharmacology and Physiology, Wiley, Vol. 43, No. 12 ( 2016-12), p. 1243-1246
Abstract:
Sarcopenia, defined by reduced appendicular skeletal muscle mass ( ASM )/height 2 ( ASMI ), is associated with increased arterial stiffness (brachial‐ankle pulse wave velocity, ba PWV ) and wave reflection (augmentation index, AI x). Blood pressure ( BP ) responses to metaboreflex activation (post‐exercise muscle ischemia, PEMI ) are exaggerated in older prehypertensives and hypertensives. We examined peripheral and aortic haemodynamics at rest and during PEMI in postmenopausal women with low‐ ASMI and normal‐ ASMI . Resting radial AI x and ba PWV as well as brachial and aortic systolic BP , pulse pressure, systolic time index, and subendocardial viability ratio ( SEVR ) responses to PEMI were greater in women with low‐ ASMI than normal‐ ASMI . Increased ba PWV associated with low‐ ASMI may play a major role in the exaggerated pulse pressure and SEVR responses to PEMI in postmenopausal women.
Type of Medium:
Online Resource
ISSN:
0305-1870
,
1440-1681
DOI:
10.1111/cep.2016.43.issue-12
DOI:
10.1111/1440-1681.12655
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
2020033-X
SSG:
15,3
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