In:
PLOS ONE, Public Library of Science (PLoS), Vol. 17, No. 2 ( 2022-2-4), p. e0263511-
Abstract:
Increasing global diabetes incidence has profound implications for health systems and for people living with diabetes. Guidelines have established clinical targets but there may be variation in clinical outcomes including HbA1c, based on location and practice size. Investigating this variation may help identify factors amenable to systemic improvement interventions. The aims of this study were to identify centre-specific and patient-specific factors associated with variation in HbA1c levels and to determine how these associations contribute to variation in performance across diabetes centres. Methods This cross-sectional study analysed data for 5,872 people with type 1 (n = 1,729) or type 2 (n = 4,143) diabetes mellitus collected through the Australian National Diabetes Audit (ANDA). A linear mixed-effects model examined centre-level and patient-level factors associated with variation in HbA1c levels. Results Mean age was: 43±17 years (type 1), 64±13 (type 2); median disease duration: 18 years (10,29) (type 1), 12 years (6,20) (type 2); female: 52% (type 1), 45% (type 2). For people with type 1 diabetes, volume of patients was associated with increases in HbA1c (p = 0.019). For people with type 2 diabetes, type of centre was associated with reduction in HbA1c (p 〈 0.001), but location and patient volume were not. Associated patient-level factors associated with increases in HbA1c included past hyperglycaemic emergencies (type 1 and type 2, p 〈 0.001) and Aboriginal and Torres Strait Islander status (type 2, p 〈 0.001). Being a non-smoker was associated with reductions in HbA1c (type 1 and type 2, p 〈 0.001). Conclusions Centre-level and patient-level factors were associated with variation in HbA1c, but patient-level factors had greater impact. Interventions targeting patient-level factors conducted at a centre level including sick-day management, smoking cessation programs and culturally appropriate diabetes education for and Aboriginal and Torres Strait Islander peoples may be more important for improving glycaemic control than targeting factors related to the Centre itself.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0263511
DOI:
10.1371/journal.pone.0263511.g001
DOI:
10.1371/journal.pone.0263511.t001
DOI:
10.1371/journal.pone.0263511.t002
DOI:
10.1371/journal.pone.0263511.t003
DOI:
10.1371/journal.pone.0263511.t004
DOI:
10.1371/journal.pone.0263511.s001
DOI:
10.1371/journal.pone.0263511.s002
DOI:
10.1371/journal.pone.0263511.s003
DOI:
10.1371/journal.pone.0263511.s004
DOI:
10.1371/journal.pone.0263511.s005
DOI:
10.1371/journal.pone.0263511.r001
DOI:
10.1371/journal.pone.0263511.r002
DOI:
10.1371/journal.pone.0263511.r003
DOI:
10.1371/journal.pone.0263511.r004
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2022
detail.hit.zdb_id:
2267670-3
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