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  • 1
    In: American Journal of Nephrology, S. Karger AG, Vol. 53, No. 8-9 ( 2022), p. 663-674
    Abstract: 〈 b 〉 〈 i 〉 Introduction: 〈 /i 〉 〈 /b 〉 Telemedicine (TM) has shown to provide potential benefits on clinical outcomes in patients with chronic kidney disease but limited evidences published in the peritoneal dialysis (PD) population. This study aimed to explore the long-term effects of TM on the mortality and technique failure. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 The Peritoneal Dialysis Telemedicine-assisted Platform Cohort Study (PDTAP Study) was conducted prospectively in 27 hospitals in China since 2016. Patient and practice data were collected through the doctor-end of the TM app (Manburs) for all participants. TM including self-monitoring records, on-line education materials, and real-time physician-patient contact was only performed for the patient-end users of the Manburs. The primary outcome was all-cause mortality. The secondary outcomes were cause-specific mortality and all-cause and cause-specific permanent transfer to hemodialysis. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 A total of 7,539 PD patients were enrolled between June 2016 and April 2019, with follow-up till December 2020. Patients were divided into two cohorts: TM group (39.1%) and non-TM group (60.9%). A propensity score was used to create 2,160 matched pairs in which the baseline covariates were well-balanced. There were significantly lower risks of all-cause mortality (HR 0.59 [0.51, 0.67], 〈 i 〉 p 〈 /i 〉 & #x3c; 0.001), CVD mortality (HR 0.59 [0.49, 0.70], 〈 i 〉 p 〈 /i 〉 & #x3c; 0.001), all-cause transfer to hemodialysis (0.57 [0.48, 0.67], 〈 i 〉 p 〈 /i 〉 & #x3c; 0.001), transfer to hemodialysis from PD-related infection (0.67 [0.51, 0.88], 〈 i 〉 p 〈 /i 〉 = 0.003), severe fluid overload (0.40 [0.30, 0.55], 〈 i 〉 p 〈 /i 〉 & #x3c; 0.001), inadequate solute clearance (0.49 [0.26, 0.92], 〈 i 〉 p 〈 /i 〉 = 0.026), and catheter-related noninfectious complications (0.41 [0.17, 0.97], 〈 i 〉 p 〈 /i 〉 = 0.041) in the TM group compared with the non-TM group. 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 This study indicated real-world associations between TM usage and reduction in patient survival and technique survival through a multicenter prospective cohort.
    Type of Medium: Online Resource
    ISSN: 0250-8095 , 1421-9670
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2022
    detail.hit.zdb_id: 1468523-1
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  • 2
    In: Nephrology Dialysis Transplantation, Oxford University Press (OUP), Vol. 39, No. 2 ( 2024-01-31), p. 251-263
    Abstract: To explore the cut-off values of haemoglobin (Hb) on adverse clinical outcomes in incident peritoneal dialysis (PD) patients based on a national-level database. Methods The observational cohort study was from the Peritoneal Dialysis Telemedicine-assisted Platform (PDTAP) dataset. The primary outcomes were all-cause mortality, major adverse cardiovascular events (MACE) and modified MACE (MACE+). The secondary outcomes were the occurrences of hospitalization, first-episode peritonitis and permanent transfer to haemodialysis (HD). Results A total of 2591 PD patients were enrolled between June 2016 and April 2019 and followed up until December 2020. Baseline and time-averaged Hb & lt;100 g/l were associated with all-cause mortality, MACE, MACE+ and hospitalizations. After multivariable adjustments, only time-averaged Hb & lt;100 g/l significantly predicted a higher risk for all-cause mortality {hazard ratio [HR] 1.83 [95% confidence interval (CI) 1.19–281] , P = .006}, MACE [HR 1.99 (95% CI 1.16–3.40), P = .012] and MACE+ [HR 1.77 (95% CI 1.15–2.73), P = .010] in the total cohort. No associations between Hb and hospitalizations, transfer to HD and first-episode peritonitis were observed. Among patients with Hb ≥100 g/l at baseline, younger age, female, use of iron supplementation, lower values of serum albumin and renal Kt/V independently predicted the incidence of Hb & lt;100 g/l during the follow-up. Conclusion This study provided real-world evidence on the cut-off value of Hb for predicting poorer outcomes through a nation-level prospective PD cohort.
    Type of Medium: Online Resource
    ISSN: 0931-0509 , 1460-2385
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2024
    detail.hit.zdb_id: 1465709-0
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  • 3
    In: Journal of Viral Hepatitis, Wiley, Vol. 26, No. S1 ( 2019-07), p. 59-68
    Abstract: Although nucleos(t)ide analog ( NA ) monotherapy is effective in hepatitis B virus suppression and fibrosis regression, serological response rates are not satisfactory. Studies assessing the benefits of combination therapy with NA s and peginterferon alpha (PegIFNα) in patients with chronic hepatitis B ( CHB ) have produced conflicting results and mainly focused on serological outcomes. Histological changes in response to combination therapy have not been evaluated in real‐world practice. This study aimed to evaluate the histological changes in response to NA ‐Peg IFN α combination therapy in CHB patients and to comprehensively compare the efficacy of NA ‐Peg IFN α combination therapy and NA monotherapy. We conducted a retrospective analysis of data from 40 CHB patients who underwent either NA ‐Peg IFN α combination therapy or NA monotherapy. Changes in histology at 48 weeks after treatment initiation were evaluated. Serological characteristics were also analysed and compared between the NA ‐Peg IFN α combination therapy and NA monotherapy groups and between histological responders and nonresponders. Compared to baseline biopsies, both fibrosis staging and necroinflammatory grading scores were significantly lower in the second biopsies examined post‐treatment in both groups. Nearly all patients experienced a reduction in inflammation (87.5% in both groups), but there was a subgroup of patients who exhibited either no significant improvement or fibrosis progression (33.3% and 31.2% in the NA monotherapy and NA ‐Peg IFN α combination therapy groups, respectively). Nearly, all patients achieved ALT normalization and sustained virological response ( SVR ) after 48 weeks of antiviral treatment. Approximately one‐third of individuals (36.8% and 30% in the two groups, respectively) achieved HB eAg loss at 48 weeks after treatment initiation. Although there were no significant differences in overall rates of histological, biochemical, virological and serological responses between the two groups, an earlier virological response and a higher cumulative SVR rate over time were observed during long‐term follow‐up in patients treated with NA ‐Peg IFN α combination therapy ( P  = 0.0129). Trends of more rapid HB eAg loss and a higher cumulative HB eAg loss rate throughout long‐term follow‐up were also observed but were not statistically significant. The ALT normalization rates at 24 and 48 weeks after treatment initiation were associated with the histological response. Significant regression of fibrosis and resolution of necroinflammation were induced with either NA ‐Peg IFN α combination therapy or NA monotherapy. Significant biochemical, virological and serological responses were observed in both groups, and the response rates at 48 weeks were similar in the two groups. Over time during long‐term follow‐up, the virological and serological responses were faster and superior following the combination regimen.
    Type of Medium: Online Resource
    ISSN: 1352-0504 , 1365-2893
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2019
    detail.hit.zdb_id: 2007924-2
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  • 4
    Online Resource
    Online Resource
    Wiley ; 2020
    In:  Journal of the American Ceramic Society Vol. 103, No. 6 ( 2020-06), p. 3716-3725
    In: Journal of the American Ceramic Society, Wiley, Vol. 103, No. 6 ( 2020-06), p. 3716-3725
    Abstract: In this study, blue‐emitting AlN:Eu 2+ spherical phosphors were successfully synthesized for the first time by the carbothermal reduction nitridation (CRN) method, assisted with high nitrogen pressure, appropriate synthesis temperature, and the addition of CaF 2 . The influence of typical experimental parameters, such as N 2 pressure, heating temperature, CaF 2 content and Eu 2+ concentration on the morphologies and luminescence properties of AlN phosphors were comprehensively investigated. The formation mechanism of spherical morphology were significantly proffered, indicating that sufficient liquid Ca‐aluminates during the AlN growth stage were essential for the spheroidization process under the action of surface tension. The synthesized AlN:Eu 2+ spherical phosphors presented an intense blue emission band centered in the range of 427‐ 476 nm relative to the reaction temperature. The lifetime of AlN:Eu 2+ phosphor was calculated to be around 1.89 μs. The temperature‐dependent PL spectra suggested that the emission band did not shift until 225°C. In addition, the spectral analysis strongly suggested that the luminescence property of AlN:Eu 2+ phosphors was significantly enhanced by the large particle size, spherical morphology, reduced impurity content, and appropriate Eu 2+ concentration.
    Type of Medium: Online Resource
    ISSN: 0002-7820 , 1551-2916
    URL: Issue
    RVK:
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 2008170-4
    detail.hit.zdb_id: 219232-9
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  • 5
    In: Small Methods, Wiley, Vol. 7, No. 3 ( 2023-03)
    Abstract: Precise control of the coordination structure of metal centers is an ideal approach to achieve reasonable selectivity, activity, and stability in the electrochemical reduction of CO 2 . In this work, the KOH activation strategy for preparation of hierarchically porous material containing Ni single‐atoms with axial‐oxygen coordination is reported. Spectroscopic measurements reveal the multiple roles of KOH as oxygen source, pore‐making reagent and promoter for the formation of key phthalocyanine structure. It exhibits superior surface area (1801 m 2  g −1 ) and electrocatalytic performance (Faradaic efficiency of 94%, Turnover frequency of 11 362 h −1 ). Notably, KOH‐enabled architecture with abundant pores benefits the anchoring of Ni atoms and mass transfer for high activity and selectivity. Density functional theory calculations suggest that the axial‐oxygen ligand can promote the electronic delocalization of the Ni site for facilitating the *COOH formation and *CO desorption to efficiently produce CO.
    Type of Medium: Online Resource
    ISSN: 2366-9608 , 2366-9608
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2884448-8
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  • 6
    Online Resource
    Online Resource
    Royal Society of Chemistry (RSC) ; 2021
    In:  Nanoscale Vol. 13, No. 4 ( 2021), p. 2181-2208
    In: Nanoscale, Royal Society of Chemistry (RSC), Vol. 13, No. 4 ( 2021), p. 2181-2208
    Type of Medium: Online Resource
    ISSN: 2040-3364 , 2040-3372
    Language: English
    Publisher: Royal Society of Chemistry (RSC)
    Publication Date: 2021
    detail.hit.zdb_id: 2515664-0
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  • 7
    In: RSC Advances, Royal Society of Chemistry (RSC), Vol. 7, No. 31 ( 2017), p. 19223-19230
    Type of Medium: Online Resource
    ISSN: 2046-2069
    Language: English
    Publisher: Royal Society of Chemistry (RSC)
    Publication Date: 2017
    detail.hit.zdb_id: 2623224-8
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  • 8
    Online Resource
    Online Resource
    American Chemical Society (ACS) ; 2023
    In:  ACS Applied Materials & Interfaces Vol. 15, No. 17 ( 2023-05-03), p. 21252-21260
    In: ACS Applied Materials & Interfaces, American Chemical Society (ACS), Vol. 15, No. 17 ( 2023-05-03), p. 21252-21260
    Type of Medium: Online Resource
    ISSN: 1944-8244 , 1944-8252
    Language: English
    Publisher: American Chemical Society (ACS)
    Publication Date: 2023
    detail.hit.zdb_id: 2467494-1
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  • 9
    Online Resource
    Online Resource
    Wiley ; 2023
    In:  Journal of the Science of Food and Agriculture Vol. 103, No. 11 ( 2023-08-30), p. 5300-5311
    In: Journal of the Science of Food and Agriculture, Wiley, Vol. 103, No. 11 ( 2023-08-30), p. 5300-5311
    Abstract: Increasing crop yield per unit area by increasing planting density is essential to ensure food security. However, the optimal combination of planting density and nitrogen (N) application for high‐yielding maize and its source–sink characteristics need to be more clearly understood. RESULTS A 2‐year field experiment was conducted combining three planting densities (D1: 70 000 plants ha −1 ; D2: 100 000 plants ha −1 ; D3: 130 000 plants ha −1 ) and three nitrogen rates (N1: 150 kg hm −2 ; N2: 350 kg hm −2 ; N3: 450 kg hm −2 ). The results showed that increasing planting density significantly increased leaf area index and grain yield but negatively affected ear traits. The Richards model was used to fit the dynamic changes of dry matter accumulation of maize under different treatments, and the fitting results were good. Increasing planting density increased population yield while limiting the development of individual plants, bringing the period of rapid dry matter accumulation to an early end and accelerating leaf senescence. An appropriate nitrogen rate could prolong the period of rapid accumulation of dry matter in maize, and increase the 100‐kernel weight. Increasing planting density enhanced post‐silking dry matter accumulation to a lesser extent, and the source–sink relationship of the maize population gradually developed from sink limitation to source limitation with increasing planting density. CONCLUSION The decrease in yield due to the insufficient source strength to meet the sink demand at too high densities was the reason that limited further improvement of the optimal planting density. An appropriate nitrogen rate facilitated the realization of yield potential at high density. © 2023 Society of Chemical Industry.
    Type of Medium: Online Resource
    ISSN: 0022-5142 , 1097-0010
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2001807-1
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  • 10
    In: Journal of the American Ceramic Society, Wiley, Vol. 105, No. 6 ( 2022-06), p. 4230-4241
    Abstract: A novel deep‐red‐emitting phosphor Ca 2 ScNbO 6 :Mn 4+ is prepared via a high‐temperature solid‐state reaction and its luminescent properties are systematically investigated. The results show that Mn 4+ ‐activated Ca 2 ScNbO 6 phosphors have broad absorption in ultraviolet region, and show bright deep‐red emission at 692 nm. The optimal doping concentration, crystal‐field strength, internal quantum efficiency, and mechanism of concentration and thermal quenching effects are discussed in detail. Moreover, NaF flux is screened out to improve both luminescent intensity and morphology of the phosphor. Finally, a red light‐emitting diode (LED) lamp is fabricated with as‐prepared Ca 2 ScNbO 6 :Mn 4+ phosphors and a 365 nm LED chip. The electroluminescence spectra show a good overlapping with phytochrome P R and P FR absorbance. The results provided the as‐synthesized Ca 2 ScNbO 6 :Mn 4+ phosphors a great potential in plant growth lighting.
    Type of Medium: Online Resource
    ISSN: 0002-7820 , 1551-2916
    URL: Issue
    RVK:
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2008170-4
    detail.hit.zdb_id: 219232-9
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