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  • 1
    In: Scientific Reports, Springer Science and Business Media LLC, Vol. 13, No. 1 ( 2023-09-14)
    Abstract: Current WHO-recommended diagnostic tools for tuberculosis infection (TBI) have well-known limitations and viable alternatives are urgently needed. We compared the diagnostic performance and accuracy of the novel QIAreach QuantiFERON-TB assay (QIAreach; index) to the QuantiFERON-TB Gold Plus assay (QFT-Plus; reference). The sample included 261 adults (≥ 18 years) recruited at community-based TB case finding events. Of these, 226 underwent Tuberculin Skin Tests and 200 returned for interpretation (TST; comparator). QIAreach processing and TST reading were completed at lower-level healthcare facilities. We conducted matched-pair comparisons for QIAreach and TST with QFT-Plus, calculated sensitivity, specificity and area under a receiver-operating characteristic curve (AUC), and analyzed concordant-/discordant-pair interferon-gamma (IFN-γ) levels. QIAreach sensitivity and specificity were 98.5% and 72.3%, respectively, for an AUC of 0.85. TST sensitivity (53.2%) at a 5 mm induration threshold was significantly below QIAreach, while specificity (82.4%) was statistically equivalent. The corrected mean IFN-γ level of 0.08 IU/ml and corresponding empirical threshold (0.05) of false-positive QIAreach results were significantly lower than the manufacturer-recommended QFT-Plus threshold (≥ 0.35 IU/ml). Despite QIAreach’s higher sensitivity at equivalent specificity to TST, the high number of false positive results and low specificity limit its utility and highlight the continued need to expand the diagnostic toolkit for TBI.
    Type of Medium: Online Resource
    ISSN: 2045-2322
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2615211-3
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  • 2
    In: Journal of Medicine and Pharmacy, Hue University of Medicine and Pharmacy
    Abstract: Purpose: Analysis about disease, technical characteristics of 17 right colon cancer patients underwent conversion to laparotomy from single port laparoscopic surgery and propose related factors for indications. Methold: Consist of 17 colon cancer patients, who were conversion to laparotomy from single port laparoscopic colectomy at Hue Central Hospital from october 2010 to august 2014. Results: Mean age 61.3±14.2 years, rate male/female 11/6. Tumor invasion: T2 11.8%, T3 58.8%, T4 29.4%. Mean tumor size on CT 6.5±2.2cm. The causes of conversion: very big tumors 29.4%, invasive-adhesive tumors 47.1%, extended surgery 23.5%. Open procedures: right hemicolectomy 70.6%, right hemicolectomy plus cholecystectomy 5.9%, right hemicolectomy plus wedge-shape duodenectomy 11.8%, right hemicolectomy plus intestinal segmentectomy 5.9% and right hemicolectomy plus low-anterior rectal resection, hysterectomy 5.9%. Conclusion: Conversion to laparotomy from single port laparoscopic colectomy is necessary for very big tumors, excessive tumor adhesions and exceed the technical limitations of laparoscopic dissection. Key words: Single incision laparoscopic colectomy (SILC), single port laparoscopic colectomy (SILC), conversion to laparotomy.
    Type of Medium: Online Resource
    ISSN: 1859-3836
    Language: Vietnamese
    Publisher: Hue University of Medicine and Pharmacy
    Publication Date: 2014
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  • 3
    In: Vietnam Journal of Science, Technology and Engineering, Ministry of Science and Technology, Vietnam (VMOST), Vol. 60, No. 3 ( 2018-9-30), p. 55-58
    Abstract: Purpose:the treatment of concomitant gallstones and common bile duct (CBD) stones by endoscopic retrograde cholangiopancreatography (ERCP) following laparoscopic cholecystectomy (LC). The analysis of single-step or separated-step characteristics. Object: during the three years (2015-2017), 68 patients having CBD stones concomitant gallstones suitable criteria for inclusion at Hue Central Hospital. Retrospective clinical description study. Results: the average age is 52.2±12.5 years (24-90) and the male/female ratio is 0.7/1 (27/41). Abdominal pain was the most common symptom 91.2%, which was followed by jaundice 51.5%; direct bilirubin increased by 27.3±15.6 μmol/l (2.2-165). The size of CBD stones is 12.4±3.2 mm (6-20), the size of gallstones is 11.3±6.2 mm (5-36). The first time CBD stones 95.6%, recurrent CBD stones 4.4%. Single-step ERCP and LC 34 patients, separated-step group: ERCP 1.4±2.5 times and secondary LC. Single-step ductal clearance 76.5%, separated-step ductal clearance 94.1% (p=0.041). Length of hospital stay 6.5±4.3 days and 13.6±2.2 days (p 〈 0.0001). Conclusions: the rate of ductal clearance in the separated-step group was significantly higher than the single-step group with p=0.041. The indication of laparoscopic cholecystectomy immediately ERCP should be based on the patient’s morbidity, the ductal clearance as well as the prognostic complications of ERCP.
    Type of Medium: Online Resource
    ISSN: 2525-2461
    URL: Issue
    Language: Unknown
    Publisher: Ministry of Science and Technology, Vietnam (VMOST)
    Publication Date: 2018
    detail.hit.zdb_id: 3145662-5
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  • 4
    In: Vietnam Journal of Science, Technology and Engineering, Ministry of Science and Technology, Vietnam (VMOST), Vol. 59, No. 2 ( 2017-6-30), p. 48-52
    Abstract: Objective: Natural Orifice Transluminal Endoscopic Surgery (NOTES) is an important evolution in minimally invasive surgery (MIS) nowaday. This paper presents the techniques and early results of the pure transanal and transvaginal laparoscopies (NOTES) used for the treatment of colorectal cancer. Material and method: Prospective studies were conducted at Hue Central Hospital, Vietnam. Patients: From December 2013 to September 2015, 22 cololorectal cancer patients (18 rectums, 3 sigmoid tumors and 1 descending colon), adenocarcinoma, T≤ T3N1M0. Methods: The patients were placed in lithotomy and Trendelenburg positions, and the lone-star retractor was placed in the anus (rectum cancer) or vagina (sigmoid cancer). The surgical cavity was then inflated with CO2 and set at 12 mm/Hg. Dissection was continued until inside of the abdominal cavity (transanal technique). After that, the rectum was pushed into the abdominal cavity. The IMA and IMV were divided (TME included) in both techniques. After finishing dissection, the specimens were pulled out through the anus or vagina to prepare anastomosis. Coloanal and colorectal anastomosis were either hand-sewn (6 cases) or sealed with EEA staplers (16 cases). Results: 2 patients needed one more 5 mm umbilical port in RLQ, 2 patients needed two 5 mm trocars (post radiation hemorrhage, and urethral perforation). One patient converted to open and 1 patient converted to the HYBRID-NOTES procedure. The operation time was 258±40 (190-300) minutes. All patients required minimal analgesia. Bowel movement returned on the first day to 16 patients (average: two days, maximum: three days). The hospital stay was 7±2.8 (4-14) days. Kirwan classification (sphincter function) was very good (stage I: 18). Conclusions: Pure transanal and transvaginal laparoscopies for the treatment of colorectal cancer are feasible and safe. We believe that this is the first pure transvaginal laparoscopy (NOTES) for human in the world. A multicentric study in a large numbers of patients and a long follow-up is necessary.
    Type of Medium: Online Resource
    ISSN: 2525-2461
    URL: Issue
    Language: Unknown
    Publisher: Ministry of Science and Technology, Vietnam (VMOST)
    Publication Date: 2017
    detail.hit.zdb_id: 3145662-5
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  • 5
    In: Ibis, Wiley, Vol. 165, No. 4 ( 2023-10), p. 1368-1377
    Abstract: Monitoring the status of endangered wildlife is a critical foundation for biodiversity conservation efforts. The use of autonomous acoustic recorders to monitor wildlife has become increasingly popular in terrestrial tropical systems. However, these recorders are expensive and not available for purchase and repair in all countries. The development of easy‐to‐use and low‐cost devices is therefore needed for applications worldwide. In this study, we modified and installed smartphone devices to operate and record sounds produced by the Vietnamese Crested Argus Rheinardia ocellata in Kon Chu Rang Nature Reserve, Vietnam, in 2021. We used the software package RAVEN to create spectrograms and to identify Crested Argus calls from acoustic recordings and used the program MARK to estimate occupancy and detection probabilities. We recorded calls of Crested Argus at 16 of 40 locations and most calls were recorded in the northern and eastern parts of the nature reserve. Our model‐averaged estimates of detection probabilities indicated that detection in the morning or afternoon was c. 0.50 and constant over seven sampling days. Our overall average occurrence probability of Crested Argus was 0.43 (standard error = ±0.08), but we found occupancy to be positively correlated with distance to the nearest village, indicating that poaching may negatively affect this species. Based on these data we suggest that the Kon Chu Rang Nature Reserve and possibly two adjacent nature reserves, namely An Toan Nature Reserve and Ba To Proposed Nature Reserve, might be important sites for Crested Argus.
    Type of Medium: Online Resource
    ISSN: 0019-1019 , 1474-919X
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2071870-6
    detail.hit.zdb_id: 2485031-7
    detail.hit.zdb_id: 2807-1
    SSG: 12
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  • 6
    Online Resource
    Online Resource
    The Japanese Society of Strategies for Cancer Research and Therapy ; 2021
    In:  Annals of Cancer Research and Therapy Vol. 29, No. 1 ( 2021-1-8), p. 68-72
    In: Annals of Cancer Research and Therapy, The Japanese Society of Strategies for Cancer Research and Therapy, Vol. 29, No. 1 ( 2021-1-8), p. 68-72
    Type of Medium: Online Resource
    ISSN: 1344-6835 , 1880-5469
    Language: English
    Publisher: The Japanese Society of Strategies for Cancer Research and Therapy
    Publication Date: 2021
    detail.hit.zdb_id: 2217374-2
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  • 7
    In: Journal of Surgery, Gavin Publishers, Vol. 9, No. 12 ( 2018-09-03)
    Type of Medium: Online Resource
    ISSN: 2575-9760
    Language: Unknown
    Publisher: Gavin Publishers
    Publication Date: 2018
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  • 8
    Online Resource
    Online Resource
    Ministry of Science and Technology, Vietnam (VMOST) ; 2017
    In:  Vietnam Journal of Science, Technology and Engineering Vol. 59, No. 4 ( 2017-12-30), p. 42-46
    In: Vietnam Journal of Science, Technology and Engineering, Ministry of Science and Technology, Vietnam (VMOST), Vol. 59, No. 4 ( 2017-12-30), p. 42-46
    Abstract: Objectives: The evaluation of feasibility, safety, and outcomes of single port laparoscopic colectomy (SPLC) for colonic cancer. Prospective study of 114 patients with colonic cancer (84 right side, 17 left side, and 13 sigmoid colon) who underwent SPLC between October 2010 and October 2016 in Hue Central Hospital. Results: Mean age of patients was 56.1±15.2 (25-87 years), male/female ratio was 70/44. Mean BMI was 23.5±2.2 kg/m2. Procedures included 84 right hemi-colectomies (73.7%), 17 left hemi-colectomies (14.9%), and 13 sigmoidectomies (11.4%). Six cases required additional ports, and 19 were converted to open surgery. Mean tumor size was 3.7±2.7 cm. Stage I: 6.1%; stage IIa: 43.9%; stage IIIa: 36.8%; and stage IIIc: 13.2%. Mean operation time was 160.5±75.5 min. There had been no deaths/intraoperative complications. Mean incisional length (including extraction) was 5.5±2.2 cm. Mean lymph nodes was 16.2±4.5. Mean hospital stay was 7.5±6.1 days. The surgical site infection rate was 3.5%, and 1 patient required reoperation (anastomotic leakage: 0.9%). After 32.2±7.5 (3-65 months) follow-up, there were no late surgical complication, incisional hernia, or incision metastasis. There were five local recurrences, and three patients developed liver metastasis in the open conversion group. The overall survival time after 2 years was 87.5%, and after 5 years, it was 59.4% (Kaplan-Meier). Conclusion: SPLC is feasible and safe procedure for the treatment of colon cancer. The cosmetic value is better (short incision confounded by umbilicus). Other outcomes were equivalent to conventional laparoscopy.
    Type of Medium: Online Resource
    ISSN: 2525-2461
    URL: Issue
    Language: Unknown
    Publisher: Ministry of Science and Technology, Vietnam (VMOST)
    Publication Date: 2017
    detail.hit.zdb_id: 3145662-5
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  • 9
    In: Vietnam Journal of Endolaparoscopic Surgery, Vietnam Association for Surgery and Endolaparosurgery, Vol. 10, No. 3 ( 2020-8-27)
    Abstract: Tóm tắt Mục tiêu: Đánh giá kết quả phẫu thuật nội soi một cổng (PTNSMC) ung thư đại tràng có theo dõi và đánh giá kết quả sống còn sau mổ. Đối tượng nghiên cứu: Nghiên cứu tiến cứu gồm 114 người bệnh (NB) ung thư đại tràng (UTĐT) được phẫu thuật nội soi một cổng từ tháng 12/2011 được theo dõi đến tháng 12/2018 tại Bệnh viện Trung ương Huế. Kết quả: Tuổi trung bình (TB) 57,1 ± 14,2 tuổi (25 - 87), tỷ lệ nam/nữ 1,6/1, tăng CEA trước mổ 54,4%, kích thước u TB 4,9 ± 2,5cm (1 - 7,5). Phương pháp phẫu thuật: cắt nửa đại tràng phải 73,7%, cắt nửa đại tràng trái 14,9%, cắt đoạn đại tràng sigma 11,4%, đặt thêm 1 trocar hỗ trợ 16,7%, không có tử vong cũng như các tai biến trong mổ. Thời gian phẫu thuật 163,5 ± 75,5 phút (120 - 290), số hạch thu được 16,2 ± 4,5 hạch (12 - 25), thời gian nằm viện 7,5 ± 6,1 ngày (6 - 15). Giai đoạn (GĐ): GĐ1: 30,7%; GĐ2: 43,9%; GĐ3: 25,4%. Thời gian theo dõi 38,2 ± 17,5 tháng (6 - 84), 5 NB tái phát tại vùng 4,4%, 3 NB tiến triển di căn xa 2,6%. Sống còn toàn bộ sau 2 năm 96,2%, sau 5 năm 75,7%, sống còn 5 năm theo giai đoạn: GĐ1: 90,9%; GĐ2: 71,6%; GĐ3: 20,8% (p 〈 0,0001). Kết luận: Phẫu thuật nội soi một cổng ung thư đại tràng là khả thi và an toàn, giá trị thẩm mỹ là vết rạch ngắn, được che phủ bởi rốn. Kết quả lâu dài về mặt ung thư học là tương tự với phẫu thuật nội soi truyền thống trong ung thư đại tràng. Abstract Objectives: Evaluation of results of single port laparoscopic surgery (SPLS) for colon cancer with follow up of survival. Materials and methods: Prospective study of 114 patients suffering from colon cancer underwent SPLS from December 2011, were followed up until December 2018 at Hue Central Hospital. Results: Average age was 57.1 ± 14.2 years (25 - 87), male/female was 1.6/1, pre-operative elevated level of CEA was 54.4%, average tumor size 4.9 ± 2.5cm (1 - 7.5). Surgical techniques included right hemicolectomy 73.7%, left hemicolectomy 14.9% and sigmoidectomy 11.4%, additional one more trocar was 16.7%. No death and nor complications were observed during surgery. Time of surgery was 163.5 ± 75.5 minutes (120 - 290), mean lymph nodes harvest 16.2 ± 4.5 nodes (12 - 25), mean hospital lenght stay was 7.5 ± 6.1 days (6 - 15). Stage I: 30.7%; stage II: 43.9%; stage III: 25.4%. Follow-up time was 38.2 ± 17.5 months (6 - 84), local recurrence was in 5 patients accounted for 4.4%, 3 patients with distal metastasis 2.6%, overall survival rates after 2 years accounted for 96.2%, after 5 years in 75.7%, 5 years of survival according to stage were : stage I in 90.9%, stage II in 71.6%, stage III in 20.8% (p 〈 0, 0001). Conclusion: Single port laparoscopic surgery for colon cancer is feasible and safe, cosmetic aspect is a short incision, hidden by the umbilicus. Long-term results in oncology are equivalent to conventional laparoscopic surgery. Keywords: Colon cancer, Single port laparoscopic surgery.
    Type of Medium: Online Resource
    ISSN: 1859-4506
    Uniform Title: Kết quả dài hạn phẫu thuật nội soi một cổng điều trị ung thư đại tràng
    URL: Issue
    URL: Issue
    Language: Vietnamese
    Publisher: Vietnam Association for Surgery and Endolaparosurgery
    Publication Date: 2020
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  • 10
    Online Resource
    Online Resource
    Vietnam Association for Surgery and Endolaparosurgery ; 2018
    In:  Vietnam Journal of Endolaparoscopic Surgery Vol. 8, No. 4 ( 2018-9-10)
    In: Vietnam Journal of Endolaparoscopic Surgery, Vietnam Association for Surgery and Endolaparosurgery, Vol. 8, No. 4 ( 2018-9-10)
    Abstract: Abstract Introduction: Patients with middle-low rectal cancer in advanced stage had many difficulties in performing laparoscopic total mesorectal excision (TME), especially in those with narrow pelvis or obese with or without neoadjuvant therapy. We conducted the study of transanal TME (TaTME) for these patients to evaluate the safety and efficacity of this technique. Material and Methods: Prospective study. Patients with middle-low rectal cancer in advanced stage underwent rectal resection with TaTME technique were enrolled. Results: 38 patients including 25 middle and 13 low rectal tumors underwent elective rectal resection by TaTME from March 2015 to September 2018. Male/female ratio: 25/13. Mean age: 58.2 ± 16.4 and BMI: 24.2 ±2.5 kg/m2. Mean operation duration:210 ± 42 minutes. Specimen were removed through abdominal incision in 23 patients and 15 via anus. Anastomoses were performed by hands in 100% patients. The protective ileostomie was performed 100%. One left ureteral burning and postoperative difficulty in voiding, one presacral abscess due to anastomotic fistula and one totally leakage of the anastomose. Good Quirke assessment in 87% patients. The distal resection margins (DRM) was 20 ± 5 mm. Distal resection margins (DRM) were negative in 100% patients and circumferential resection margins (CRM) were positive in one (2.6%) patients. The hospital stay was 6 days. Median follow-up time was 12 months. One patient had local recurrence at 18th months and 1 had liver metastasis at 6th months. Conclusion: TaTME for patients with middle-low rectal cancer in advanced stage is safe and efficacious. However, there is a need for large, multicentric studies to accurately evaluate this technique.
    Type of Medium: Online Resource
    ISSN: 1859-4506
    URL: Issue
    URL: Issue
    Language: English
    Publisher: Vietnam Association for Surgery and Endolaparosurgery
    Publication Date: 2018
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