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  • 1
    In: Pediatric Cardiology, Springer Science and Business Media LLC, Vol. 38, No. 2 ( 2017-2), p. 215-227
    Type of Medium: Online Resource
    ISSN: 0172-0643 , 1432-1971
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2017
    detail.hit.zdb_id: 1463000-X
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  • 2
    Online Resource
    Online Resource
    Professional Edition Eastern Europe ; 2022
    In:  Ukrainian Journal of Cardiovascular Surgery Vol. 30, No. 4 ( 2022-12-26), p. 53-58
    In: Ukrainian Journal of Cardiovascular Surgery, Professional Edition Eastern Europe, Vol. 30, No. 4 ( 2022-12-26), p. 53-58
    Abstract: The aim. To assess the effectiveness and safety of transcatheter closure of a secondary atrial septal defect (ASD) using an occluder in symptomatic children weighing ≤10 kg. Materials and methods. In the period from November 2014 to June 2021, on the basis of the National Amosov Institute of Cardiovascular Surgery of the National Academy of Medical Sciences of Ukraine, closure of secondary ASD using an occluder was performed in 18 patients, among them 13 women (72.2%) and 5 men (27.8%). Th e mean age of the patients was 18.94±9.44 months (the youngest patient was 12 months, the oldest was 4 years). The mean weight was 9.294±1.170 kg (6.4 kg to 10 kg), the mean Z-score was -1.7±1.5 (-4.6 to 0.46), the mean height was 80 cm (71 cm to 88 cm). According to the measurements by transesophageal echocardiography (TEE), the average size of the defects was 13.7 mm±3.6mm (the largest 18.0 mm, the smallest 6.0 mm). Results and discussion. In our publication, the effectiveness of the method was 100% (18/18), while the world statistics show 94-95%. Th e frequency of complications was 5.6% (n=1). We suggest that this is associated with the use of a sizing balloon and careful selection of the device. When choosing treatment tactics for symptomatic children weighing ≤10 kg, the decisive factor was the determination of the presence of edges and the size of the defect. Defects were considered suitable for closure, according to TEE data, when all margins of the defect were ≥4 mm, except for the aortic margin. Although the total length of the interatrial membrane was taken into account, it was not of decisive importance, since for most occluders with the presence of all edges, the fields of the implant could not interfere with the work of the anatomical structures of the heart. To determine the real size of the defect, we recommend a measuring balloon under TEE control. The following devices were used to close the defect: MemoPart ASD occluder, Amplatzer Septal Occluder, LifeTech HeartR Occluder, LifeTech HeartR Multi-Fenestrated Atrial Septal Defect (MF-ASD) Occluder.   Conclusion. After the study, we are convinced that the endovascular method of closing a hemodynamically significant secondary ASD for the treatment of children with a body weight of ≤10 kg has proven to be an effective method, with successful implantation of the occluder in 100% of cases.
    Type of Medium: Online Resource
    ISSN: 2664-5971 , 2664-5963
    Language: Unknown
    Publisher: Professional Edition Eastern Europe
    Publication Date: 2022
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  • 3
    In: Catheterization and Cardiovascular Interventions, Wiley, Vol. 88, No. 4 ( 2016-10), p. 571-581
    Abstract: The Occlutech Figulla ASD device series (OFSO) shows an improved device design for interventional ASD closure, larger follow‐up series are missing. Methods We retrospectively reviewed the feasibility, safety, implantation properties, results, and follow‐up of ASD closure using Occlutech devices over a 5 year period by establishing a multi‐institutional collaborative result registry with 16 contributing centers from 11 countries (IRFACODE). Results In 1315 patients of all age groups (female 66.9%), successful (98%) ASD closure was performed (mean age 28.9 years, weight 52 kg, height 148.6 cm). Of the defects, 47.9% showed no or only a deficient aortic rim; in 11.9%, there was more than one defect; a septum aneurysm was present in 21.5%; and the mean implanted device size was 20.5 mm. Immediate closure was achieved in 78.6%, at discharge in 83.1%, and 96.4% and 97.3% at 6 and 12 months follow‐up, respectively. During a mean follow‐up of 2.7 years (in total 3597 patient years), significant complications were minimal (total = 8, 〈 1%) with secondary device embolizations in five and AV‐blocks in three patients. No erosion or death was reported. Conclusion ASD closure using OFSO is feasible in a large variety of patients, safe with only a minimal risk of severe side effects and especially without any aortic erosions despite a large percentage of large and complicated defects. © 2016 Wiley Periodicals, Inc.
    Type of Medium: Online Resource
    ISSN: 1522-1946 , 1522-726X
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2016
    detail.hit.zdb_id: 2001555-0
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  • 4
    In: Journal of Medicine and Life, S.C. JURNALUL PENTRU MEDICINA SI VIATA S.R.L, Vol. 15, No. 2 ( 2022-2), p. 222-227
    Abstract: The hybrid method of treating thoracic aortic pathology is devoid of the disadvantages of traditional open surgery and, at the same time, has a broader range of applications than the endovascular method. From 2014 to 2019, we researched 122 patients with thoracic aortic pathology treated with the hybrid method (open surgery with thoracic endovascular aortic repair (TEVAR) at the National M. Amosov Institute of Cardiovascular Surgery National Academy of Medical Science of Ukraine. In the general group, 34 patients had a descending aortic aneurysm without dissection or rupture; 71 patients had an aortic dissection (10 – acute, 9 – subacute, 52 – chronic), penetrating aortic ulcer (PAU) – 7, thoracoabdominal aneurysm (Crawford I-II) – 4, isolated aortic arch aneurysm – 2, residual enlargement aorta after previous ascending aortic grafting causing type A acute aortic dissection (TAAD) – 3, primary aortic thrombosis – 1. Patients admitted as elective surgery candidates had switched aortic arch vessels (debranching) in the first stage and TEVAR in the second stage. For emergencies (aortic rupture with uncontrolled bleeding, malperfusion syndrome), TEVAR operation was performed first. Long-term results of treatment after three and six months are satisfactory. The hybrid technique of aortic arch treatment using modern minimally invasive technologies can eliminate the pathology in the most dangerous segment of the main artery of the body, providing a reasonable level of hospital mortality – 4.2%, and a small number of neurological complications.
    Type of Medium: Online Resource
    ISSN: 1844-122X , 1844-3117
    Language: English
    Publisher: S.C. JURNALUL PENTRU MEDICINA SI VIATA S.R.L
    Publication Date: 2022
    detail.hit.zdb_id: 2559353-5
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  • 5
    Online Resource
    Online Resource
    Professional Edition Eastern Europe ; 2021
    In:  Ukrainian Journal of Cardiovascular Surgery , No. 4 (45) ( 2021-12-22), p. 71-84
    In: Ukrainian Journal of Cardiovascular Surgery, Professional Edition Eastern Europe, , No. 4 (45) ( 2021-12-22), p. 71-84
    Abstract: The aim. To analyze the 10-year experience in aortic coarctation endovascular stenting in patients of different age groups. Materials and methods. Examination and endovascular treatment of 194 patients aged 3 days to 60 years with coarctation of the aorta (CoA) with different anatomical and morphological variants was performed. According to the age criterion, the examined patients were divided into 4 study groups. The first group consisted of 84 patients (43.3%) over 25 years of age, group 2 included 33 patients (17.0%) aged 19 to 25 years, group 3 included 71 patients (36.6%) aged 5 to 18 years, and group 4 included 6 patients (3.1%) under 1 year of age. Results and discussion. We presented the clinical features of different anatomical and morphological variants of CoA. Endovascular treatment of CoA with stenting is considered the best method for adolescents and adults, due to the lower risk of aneurysm formation compared to balloon angioplasty. We were able to successfully reduce the invasive pressure gradient in patients of different ages and to establish the dependence of complication rate on the stent type used. The most common complications were aneurysm formation (2.1%) and stent migration (2.1%). Complications occurred more often in cases of uncovered stents compared to stent grafts (5.3% and 2.1%, respectively, p 〈 0.05). No cases of hospital mortality were recorded in patients older than 5 years. Seven endovascular procedures were performed in 5 patients aged 3 days to 11 months (mean age 3.5 ± 1.6 months) with combined heart defects. Complications were documented in 1 child (20.0%). Endovascular intervention in pregnant women is indicated in refractory hypertension. We performed endovascular CoA stenting in 4 pregnant women at 15–23 weeks of gestation (average, 19.8 ± 3.1 weeks), and in 6 women with well-controlled hypertension stenting was performed within 48 hours to 5 years after delivery. In all the presented cases, successful revascularization was achieved. During follow-up (from 2 months to 10 years), all 10 women are alive, did not develop recoarctation or complications. Conclusions. The results of the analysis of CoA endovascular treatment showed that the chosen method and technique of intervention is appropriate and safe for patients of all ages, including pregnant women. Based on the results obtained, we have developed an algorithm for the management of patients who, according to clinical examination and echocardiography, were diagnosed with CoA during pregnancy.
    Type of Medium: Online Resource
    ISSN: 2664-5971 , 2664-5963
    Language: Unknown
    Publisher: Professional Edition Eastern Europe
    Publication Date: 2021
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  • 6
    Online Resource
    Online Resource
    Professional Edition Eastern Europe ; 2022
    In:  Ukrainian Journal of Cardiovascular Surgery Vol. 30, No. 3 ( 2022-09-26), p. 76-82
    In: Ukrainian Journal of Cardiovascular Surgery, Professional Edition Eastern Europe, Vol. 30, No. 3 ( 2022-09-26), p. 76-82
    Abstract: The aim. To analyze the results of the use of endovascular treatments for pulmonary artery atresia (PAA). Materials and methods. Treatment of this heart defect at the National Amosov Institute of Cardiovascular Surgery of the NAMS of Ukraine with application of endovascular methods began in 2006. Since then, 138 patients were operated, 57 of them female (41.3%) and 81 (58.6%) were male. Endovascular methods were used in 23 patients, and 115 patients underwent open-heart surgery. The mean length of hospital stay was 25±16.3 days. Of 115 patients who underwent open-heart surgery, 62 (54%) were male and 53 (46%) were female. On the day of surgery, the mean age of these patients was 607.8±1023.7 days, mean weight was 8.8±8.1 kg. The average length of hospital stay was 26±18.6 (maximum 215, minimum 5). Of 23 patients who underwent endovascular surgery, 18 (77%) were male and 5 (23%) were female. The mean age on the day of surgery was 220.5±650.2 days, mean weight was 5.0±4.4 kg. The mean length of hospital stay was 22±5.7 days (maximum 34, minimum 4). In the treatment of PAA, a stepwise procedure is used, correcting part of the defect at each stage and thereby reducing the traumaticity of the operation. In our case, correction of the defect was performed on the open heart and using endovascular methods of treatment. After endovascular interventions, no fatal effects were observed. Open-heart surgery was performed in case if endovascular interventions could not be performed. The condition of such patients was usually more severe. It should also be noted that the open-heart surgery itself is a serious trauma to the body. Due to the above, postoperative period in this group of patients more often proceeded with complications. Due to more severe preoperative condition of the patients and surgical trauma, in some cases of open-heart interventions, some patients did not recover after surgery. As a result, the total mortality in the group of patients who underwent open-heart surgery was 13.0%. In addition, in 7 cases, such surgery was supplemented by the Rashkind procedure. In case of recurrent surgery after 6 months, stenting of patent ductus arteriosus was performed. Repeated surgical interventions were accompanied by the improvement of the condition and the patients were discharged from the clinic in satisfactory condition. Conclusions. PAA is one of the most complex congenital pathologies of the heart and main vessels, and therefore preservation of such a newborn depends on the preservation of patent ductus arteriosus. Endovascular surgery for PAA is the operation of choice that allows to prepare the patient for the next stage of treatment, including open-heart surgery. Endovascular interventions in PAA are minimally invasive, which increases the chances of patients with complicated anatomy to survive despite their serious condition on admission to the hospital.
    Type of Medium: Online Resource
    ISSN: 2664-5971 , 2664-5963
    Language: Unknown
    Publisher: Professional Edition Eastern Europe
    Publication Date: 2022
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  • 7
    Online Resource
    Online Resource
    Professional Edition Eastern Europe ; 2023
    In:  Ukrainian Journal of Cardiovascular Surgery Vol. 31, No. 1 ( 2023-03-27), p. 36-44
    In: Ukrainian Journal of Cardiovascular Surgery, Professional Edition Eastern Europe, Vol. 31, No. 1 ( 2023-03-27), p. 36-44
    Abstract: According to European guidelines, endovascular closure is the method of choice for defects with favorable anatomy. However, there are no clear criteria for determining favorable anatomy and this issue requires additional investigation. According to literature data, only 24.2% of secundum atrial septal defects (ASDII) have a central location, others have complicated anatomy. The aim. To analyze the experience of endovascular closure of ASDII with complex anatomy. Materials. In the period from 2003 to 2021, 1732 transesophageal echocardiographies and intracardiac echocardiographieswereperformedinpatientswithASDIIinitiallydiagnosedaccordingtotransthoracicechocardiography, and only 1408 (91.8%) were selected for endovascular closure. Mean age was 19.9±18 years, mean weight was 45±26.68 kg. Methods. The standard closure technique was primarily used in 100% of cases, and only when it was ineffective, we used modified techniques. Results. Modified techniques were used in 478 (33.9%) of 1408 patients and were effective in 460 (96.2%) patients with the complex anatomy. Based on previous statement, 460 (32.6%) of 1408 patients (one third of all) had modified techniques utilized and avoided open surgery. In 18 (1.3%) cases, it was impossible to close the defect. The overall technical success of transcatheter closure was 98.7% (1390 patients). Nineteen (1.3%) patients with poor visualization of inferior rim on transesophageal echocardiography had intracardiac echocardiography; in two of them inferior rim was present, others had open surgery. The rate of complications in immediate periprocedural period was 1.9% (27 patients). One death was recorded in the period of introduction of percutaneous interventions in our institution. Mean follow-up period was 5.41±3.28 years. In the follow-up period two complications were observed: 1 case of erosion, 17 (1.9%) cases of new-onset atrial fibrillation. Conclusion. The majority (90.6%) of ASDII can be closed percutaneously. Modified techniques improve the efficacy of the procedure enabling to close 32.6% of the defects. Safe procedure for the defects with complex anatomy is possible only with surgical and arrhythmological services back-up.
    Type of Medium: Online Resource
    ISSN: 2664-5971 , 2664-5963
    Language: Unknown
    Publisher: Professional Edition Eastern Europe
    Publication Date: 2023
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  • 8
    In: Journal of Cardiology, Elsevier BV, Vol. 74, No. 4 ( 2019-10), p. 381-387
    Type of Medium: Online Resource
    ISSN: 0914-5087
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2019
    detail.hit.zdb_id: 2422407-8
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