In:
Canadian Journal of Animal Science, Canadian Science Publishing, Vol. 100, No. 1 ( 2020-03-01), p. 85-92
Abstract:
Leukemia inhibitory factor (LIF) is an important productivity-related gene in pigs. We found two polymorphisms — g.6646C 〉 T and g.6988C 〉 T — in exon 3 of LIF in pigs by using DNA sequencing and polymerase chain reaction-restriction fragment length polymorphism. Three genotypes were obtained and associated with litter size traits in Anqing Six-end-white (AQ), Wei (W), Wannan Black (WNB), and Large White (LW) pigs. At locus g.6646C 〉 T, the g.6646C allele frequency variation was 0.6869 (AQ), 0.7473 (W), 1 (WNB), and 0.6852 (LW). In AQ pigs, sows with the TT genotype had higher total number of piglets born (TNB) and number of piglets born alive (NBA) in the first parity and multiparities (P 〈 0.01). In W and LW pigs, sows with the CC genotype had higher TNB and NBA in multiparities (P 〈 0.01). At locus g.6988C 〉 T, the g.6988C allele frequency variation was 1 (AQ), 0.6154 (W), 1 (WNB), and 0.6667 (LW). The CC genotype significantly differed from CT or TT genotypes (P 〈 0.01) for TNB and NBA in W and LW pigs. Thus, LIF was shown to have a significant influence on litter size. Therefore, g.6646C 〉 T and g.6988C 〉 T loci of LIF could be potential marker-assisted selection tools for improving litter size in pig production.
Type of Medium:
Online Resource
ISSN:
0008-3984
,
1918-1825
DOI:
10.1139/cjas-2018-0228
Language:
English
Publisher:
Canadian Science Publishing
Publication Date:
2020
detail.hit.zdb_id:
2016977-2
detail.hit.zdb_id:
417253-X
SSG:
22
SSG:
12
Permalink