In:
Journal of Biomedical and Clinical Research, Walter de Gruyter GmbH, Vol. 10, No. 1 ( 2017-11-1), p. 37-39
Kurzfassung:
The reaction of anti-sperm antibody-positive sera from infertile women with fractionated mouse ovarian antigens was measured by enzyme-linked immunosorbent assay (ELISA). Antigens were obtained by extraction for nuclear matrix and intermediate filaments (NM-IF) producing three protein fractions – soluble, cytoskeletal and NM-IF. The results showed that sera from some infertile patients, but not control sera, react with either the soluble fraction or the NM-IF fraction. The reaction with soluble proteins was most likely directed against surface antigens, possibly aggravating the fertility problems, while the anti-NM-IF antibodies could indicate release of insoluble intracellular components by tissue damage of unknown origin.
Materialart:
Online-Ressource
ISSN:
1313-9053
DOI:
10.1515/jbcr-2017-0007
Sprache:
Englisch
Verlag:
Walter de Gruyter GmbH
Publikationsdatum:
2017
ZDB Id:
2860343-6
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