In:
European Journal of Organic Chemistry, Wiley, Vol. 2011, No. 26 ( 2011-09), p. 5002-5011
Abstract:
The titanocene‐mediated cyclization of suitably functionalized acyclic C10 epoxy‐polyprenes leads, with moderate stereoselectivity, to high yields of functionalized terpenic cyclopentanes with three contiguous stereogenic centers. These highly functionalized cyclopentanes are useful intermediates for the synthesis of several natural compounds that include this interesting subunit in their structure. Both the regioselectivity of the process leading to cyclopentanes and the stereoselectivity of the cyclization could be controlled by using malonyl derivatives or α,β‐unsaturated nitriles as radical acceptors.
Type of Medium:
Online Resource
ISSN:
1434-193X
,
1099-0690
DOI:
10.1002/ejoc.v2011.26
DOI:
10.1002/ejoc.201100400
Language:
English
Publisher:
Wiley
Publication Date:
2011
detail.hit.zdb_id:
1475010-7
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