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  • 1
    Online Resource
    Online Resource
    Nepal Journals Online (JOL) ; 2020
    In:  Journal of Brain and Spine Foundation Nepal Vol. 1, No. 1 ( 2020-10-16), p. 16-19
    In: Journal of Brain and Spine Foundation Nepal, Nepal Journals Online (JOL), Vol. 1, No. 1 ( 2020-10-16), p. 16-19
    Abstract: Introduction: Incidence of stroke patients is increasing in low income countries like Nepal where management of these patients is challenging due to poor healthcare resources. Ischemic stroke is related to risk factors like age, male population, hypertension, diabetes mellitus, smoking and alcohol. Identification of these risk factors in the vulnerable population is important for prevention of ischemic stroke. The purpose of this study is to find out the social and demographic characteristics of patients with acute ischemic stroke treated at Upendra Devkota Memorial National Institute of Neurological and Allied Sciences, a tertiary care hospital of Nepal. Methods: Data was collected from all acute ischemic stroke patients presenting to the hospital over a period of one year. The age, sex, medical history of hypertension and diabetes and history of smoking and alcohol consumption were recorded. Statistical analysis of data was performed using Microsoft EXCEL 2019. Result: Total 310 patients were studied, out of which two-thirds were male. The highest number of patients were within the age group of 60-80 years with the mean age being 60 years. Hypertension and diabetes were present in 67.42% and 28.53% of patients respectively. 43.93% of the patients smoked while 33.87% of the patients consumed alcohol. Conclusion: Identification of association between risk factors like age, sex, hypertension, diabetes mellitus, smoking and alcohol consumption must be the emphasis for targeted preventive action to decrease the increasing burden of ischemic stroke among developing countries.
    Type of Medium: Online Resource
    ISSN: 2738-960X , 2738-9561
    Language: Unknown
    Publisher: Nepal Journals Online (JOL)
    Publication Date: 2020
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  • 2
    In: Atoms, MDPI AG, Vol. 10, No. 4 ( 2022-10-24), p. 119-
    Abstract: We performed a fully differential experimental and theoretical study on ionization of He in intermediate-energy collisions with protons for a small projectile coherence length. Data were taken for an ejected electron energy corresponding to a speed close to the projectile speed (velocity matching). In the fully differential angular electron distributions, a pronounced double-peak structure, observed previously for a coherence length much larger than the atomic size, is much less pronounced in the current data. This observation is interpreted in terms of interference between first-and higher-order transition amplitudes. Although there is large quantitative disagreement between experiment and theory, the qualitative agreement supports this interpretation.
    Type of Medium: Online Resource
    ISSN: 2218-2004
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2704220-0
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  • 3
    In: Journal of Nepal Medical Association, Journal of Nepal Medical Association (JNMA), Vol. 61, No. 260 ( 2023-04-01), p. 343-346
    Abstract: Introduction: Chronic obstructive pulmonary disease is a preventable and treatable disease marked by persistent airflow limitation. Abnormal rise of haemoglobin and/or hematocrit in peripheral blood is known as polycythemia which includes increased haemoglobin: greater than 16.5 g/dl in men or greater than 16.0 g/dl in women and increased hematocrit: 〉 49% for men and 〉 48% for women. Men, current smoking, impaired carbon monoxide diffusing capacity, severe hypoxemia, and high altitude living are risk factors associated with an increased risk for secondary polycythemia. Polycythemia contributes to the development of cor-pulmonale and pulmonary hypertension, which are linked to poor prognosis. This study aimed to find out the prevalence of polycythemia among patients with chronic obstructive pulmonary disease admitted to the department of medicine in a tertiary care centre. Methods: A descriptive cross-sectional study was conducted among patients with chronic obstructive pulmonary disease admitted to the Department of Medicine in a tertiary care centre after receiving ethical approval from Institutional Review Committee (Reference number: 153/079/080). The study was conducted from 15 September 2022 to 2 December 2022. Data were collected from the hospital records. A convenience sampling method was used. Point estimate and 95% Confidence Interval were calculated. Results: Among 185 patients, Polycythemia was seen in 8 (4.32%) (1.39-7.25, 95% Confidence Interval) patients among which 7 (87.5%) were females and 1 (12.5%) were male. Conclusions: The prevalence of polycythemia was lower compared to other similar studies done in similar settings.
    Type of Medium: Online Resource
    ISSN: 1815-672X , 0028-2715
    Language: Unknown
    Publisher: Journal of Nepal Medical Association (JNMA)
    Publication Date: 2023
    detail.hit.zdb_id: 2209910-4
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  • 4
    In: Interdisciplinary Perspectives on Infectious Diseases, Hindawi Limited, Vol. 2022 ( 2022-6-15), p. 1-12
    Abstract: Background. Patients infected with coronavirus disease 2019 (COVID-19) present with various clinical presentations with majority of them developing pulmonary complications. This study focuses on cardiac implications of COVID-19 which are less discussed and thus will help to address cardiac implications of COVID-19. Methods. PubMed, PubMed Central, and Google Scholar were screened for articles which mentioned cardiac implications of COVID-19. NHLBI Study Quality Assessment Tools for the observational cohort and cross-sectional studies was used for assessing the risk of bias of our studies. Results. All 14 studies selected were good and had score of ≥9 by NHLBI Study Quality Assessment Tools. Cardiac complications of COVID-19 are common. They are associated with significant mortality. Also, people infected with COVID-19 with premorbid conditions such as cardiovascular diseases and diabetes mellitus have poor prognosis as compared to those without premorbid conditions. Cardiac biomarkers such as highly sensitive troponin I, creatinine, and creatinine kinase-MB on admission are good prognostic markers. Conclusions. Cardiac complications such as heart failure, myocardial injury, and arrhythmias are common among patients infected with COVID-19. Elevated cardiac markers and patients with cardiac complications require utmost care and continuous cardiac monitoring.
    Type of Medium: Online Resource
    ISSN: 1687-7098 , 1687-708X
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2022
    detail.hit.zdb_id: 2478373-0
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  • 5
    Online Resource
    Online Resource
    Nepal Journals Online (JOL) ; 2019
    In:  Journal of Advanced College of Engineering and Management Vol. 5 ( 2019-12-18), p. 153-164
    In: Journal of Advanced College of Engineering and Management, Nepal Journals Online (JOL), Vol. 5 ( 2019-12-18), p. 153-164
    Abstract: Concrete is weak in tension, hence some measures must be adopted to overcome this deficiency as well as to enhance physical and other mechanical properties but in more convenient and economical method. Through many research from the past, it has been observed that addition of different types of fibres has been more effective for this purpose. This report presents the work undertaken to study the effect of steel and hay fibre on normal cement concrete of M-15 Grade on the basis of its mechanical properties which include compressive and tensile strength test and slump test as well. Although hay fibres are abundantly available in Nepal, no research have been popularly conducted here regarding the use of hay fibres in concrete and the changes brought by it on concrete’s mechanical properties. Experiments were conducted on concrete cubes and cylinders of standard sizes with addition of various percentages of steel and hay fibres i.e. 0.5%, 1% and 1.5% by weight of cement and results were compared with those of normal cement concrete of M-15 Grade. For each percentage of steel and hay fibre added in concrete, six cubes and six cylinders were tested for their respective mechanical properties at curing periods of 14 and 28 days. The results obtained show us that the optimum content of fibre to be added to M-15 grade of concrete is 0.5% steel fibre for compression and 0.5% hay fibre content for tension by weight of cement. Also, addition of steel and hay fibres enhanced the binding properties, micro cracking control and imparted ductility. In addition to this, two residential buildings were modeled in SAP software, one with normal concrete and other with concrete containing 0.5% steel fibre. Difference in reinforcement requirements in each building was computed from SAP analysis and it was found that 489.736 Kg of reinforcement could be substituted by 158.036 kg of steel fibres and decrease in materials cost of building with 0.5% steel fibre reinforced concrete was found to be Rs. 32,100.
    Type of Medium: Online Resource
    ISSN: 2392-4853
    Language: Unknown
    Publisher: Nepal Journals Online (JOL)
    Publication Date: 2019
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  • 6
    In: F1000Research, F1000 Research Ltd, Vol. 11 ( 2022-9-14), p. 1049-
    Type of Medium: Online Resource
    ISSN: 2046-1402
    Language: English
    Publisher: F1000 Research Ltd
    Publication Date: 2022
    detail.hit.zdb_id: 2699932-8
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