In:
Chemical Biology & Drug Design, Wiley, Vol. 72, No. 1 ( 2008-07), p. 3-15
Abstract:
In this article, we compare drugs of natural origin to synthetic compounds and analyze the reasons why natural compounds occupy a place of choice in the current pharmacopoeia. The observations reported here support the design of synthetic compounds inspired from plant alkaloids and their biosynthetic pathway. Our reasoning leads to very efficient syntheses of compounds which complexity matches that of indolomonoterpenic alkaloids.
Type of Medium:
Online Resource
ISSN:
1747-0277
,
1747-0285
DOI:
10.1111/jpp.2008.72.issue-1
DOI:
10.1111/j.1747-0285.2008.00673.x
Language:
English
Publisher:
Wiley
Publication Date:
2008
detail.hit.zdb_id:
2216600-2
SSG:
12
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