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  • 1
    Online Resource
    Online Resource
    Characteristics of acute diarrhea under the sentinel surveillance system at the Vietnam National Children’s Hospital from 2018 to 2022
    Tap chi Y hoc du phong (Vietnam Journal of Preventive Medicine-VJPM) ; 2024
    In:  Tạp chí Y học Dự phòng Vol. 33, No. 8 ( 2024-03-20), p. 49-56
    Details
    In: Tạp chí Y học Dự phòng, Tap chi Y hoc du phong (Vietnam Journal of Preventive Medicine-VJPM), Vol. 33, No. 8 ( 2024-03-20), p. 49-56
    Abstract: The study describes a sentinel diarrhea surveillance system at the Vietnam National Children’s Hospital from 2018 - 2022, characterizing the epidemiology of acute diarrhea (AD) due to rotavirus (RV) and identifying circulating RV strains. Of 4,765 AD cases, 861 were positive for RV, accounting for 18.07%. The disease appeared in all months, peaking in the winter-spring months (from October to March of the following year). The groups of children aged 6 - 11 months, 12 - 23 months, and 6 weeks-6 months had the highest number of cases, but the highest positive rate is 24 - 47 months old. About 24% of RV patients under 2 years of age have already been vaccinated, while this proportion among 3 - 5 years of age patients is 41%. Dehydration and no dehydration account for 96,7%, while severe dehydration only accounts for 3.3%, the prevalent RV types identified were G3P[8], G8P[8] , G1P[8], G9P[8] , which account for 50.7%, 20.6%, 11.4%, and 9%, respectively and changed annually. It is necessary to implement RV vaccines in the Expanded Program on Immunization. Meanwhile maintaining an RV sentinel surveillance system and continuing research on the effectiveness of RV vaccines in Viet Nam are also critical for controlling RV in Vietnam.
    Type of Medium: Online Resource
    ISSN: 0868-2836
    URL: Article
    DOI: 10.51403/0868-2836/2023/1477
    Language: Unknown
    Publisher: Tap chi Y hoc du phong (Vietnam Journal of Preventive Medicine-VJPM)
    Publication Date: 2024
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  • 2
    Online Resource
    Online Resource
    Phát hiện một số vi rút gây bệnh ở người trong môi trường nước thải tại Hà Nội, năm 2020 – 2021
    Tap chi Y hoc du phong (Vietnam Journal of Preventive Medicine-VJPM) ; 2022
    In:  Tạp chí Y học Dự phòng Vol. 32, No. 7 ( 2022-11-18), p. 30-39
    Details
    In: Tạp chí Y học Dự phòng, Tap chi Y hoc du phong (Vietnam Journal of Preventive Medicine-VJPM), Vol. 32, No. 7 ( 2022-11-18), p. 30-39
    Abstract: Giám sát tác nhân vi rút gây bệnh ở người trong nước thải là mô hình giám sát sức khỏe cộng đồng chủ động được nhiều quốc gia áp dụng. Tại Việt Nam, chưa có công bố nào về giám sát các vi rút gây bệnh trong nước thải. Dựa vào chương trình giám sát vi rút polio trong nước thải được triển khai tại Hà Nội từ tháng 11/2020, nghiên cứu này nhằm mục tiêu xác định sự có mặt của một số vi rút gây bệnh khác. 53 mẫu nước thải chưa qua xử lý được thu thập từ hai trạm xử lý và bốn cống gom nước thải sinh hoạt ở các sông tại Hà Nội, giai đoạn 11/2020 – 12/2021. Mẫu nước được cô đặc theo phương pháp 2-pha Dextran PEG và sau đó xét nghiệm phát hiện vi rút đường ruột (VRĐR), rota, noro và adeno. VRĐR phân lập được trên 6 (11,32%) mẫu, bao gồm echo 3, 6 và 11, mỗi type 2 mẫu. Vi rút rota, noro GI, noro GII và adeno lần lượt phát hiện trên 24 (45,28%), 16 (30,18%), 27 (50,94%) và 33 (62,26%) mẫu. Kết quả bước đầu cho thấy tính khả thi trong việc kết hợp song song giám sát vi rút polio với giám sát các vi rút gây bệnh khác trong môi trường nước thải, đặc biệt đối với vi rút noro và adeno mà hệ thống giám sát dựa trên bệnh nhân chưa được thực hiện tại Việt Nam.
    Type of Medium: Online Resource
    ISSN: 0868-2836
    URL: Article
    DOI: 10.51403/0868-2836/2022/839
    Language: Unknown
    Publisher: Tap chi Y hoc du phong (Vietnam Journal of Preventive Medicine-VJPM)
    Publication Date: 2022
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  • 3
    Online Resource
    Online Resource
    Protection and Rehabilitation Effects of Cordyceps militaris Fruit Body Extract and Possible Roles of Cordycepin and Adenosine
    MDPI AG ; 2022
    In:  Compounds Vol. 2, No. 4 ( 2022-12-19), p. 388-403
    Details
    In: Compounds, MDPI AG, Vol. 2, No. 4 ( 2022-12-19), p. 388-403
    Abstract: Cordyceps militaris is a valued medicinal fungus in folk medicine in East Asia. It contains two major nucleosides, cordycepin and adenosine, which have been reported to have potential antineoplastic, antioxidant, and anti-inflammatory activities. This paper aimed to study the effect of C. militaris extract on the reproductive function of a mouse model, evaluating possible toxicity, androgenic activity, and protective and rehabilitative effects against damages caused by sodium valproate (VPA). There was no death and abnormalities observed in mice. Androgen activity was also shown in young male rats by an improvement in several sexual organs. The protective effect of C. militaris extract was explained by the gain of sexual organs’ weight, testosterone concentration, and seminiferous tubule size as well as the enhancement of sperm density, alive sperm percentage, and the progressive forward movement of sperm. The pregnancy rate of female rats paired with VPA-administered male rats (500 mg/kg/day) increased proportionally with the higher dose of C. militaris extract. In the rehabilitation study, an incline in the weight of the Cowper’s gland and glans (0.112 g/kg/day) and testicle and prostate (0.336 g/kg/day) as well as an improvement of the sperm forward progressive movement was observed. The percentage of unprogressive sperm and immotile sperm has reduced. These results suggest that C. militaris is a potential supplement to reduce the negative effects of VPA and improve reproductive function, in which the two major constituents cordycepin and adenosine may play an active role.
    Type of Medium: Online Resource
    ISSN: 2673-6918
    URL: Article
    DOI: 10.3390/compounds2040032
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
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  • 4
    Online Resource
    Online Resource
    Giá trị lâm sàng của Cystatin C huyết thanh trong dự đoán mức lọc cầu thận ở bệnh nhân đái tháo đường típ 2
    Vietnam Association of Diabetes and Endocrinology ; 2021
    In:  Vietnam Journal of Diabetes and Endocrinology , No. 41 ( 2021-01-06), p. 79-87
    Details
    In: Vietnam Journal of Diabetes and Endocrinology, Vietnam Association of Diabetes and Endocrinology, , No. 41 ( 2021-01-06), p. 79-87
    Abstract: Mục tiêu: Khảo sát nồng độ và giá trị lâm sàng của Cystatin C huyết thanh trong dự đoán mức lọc cầu thận ở bệnh nhân ĐTĐ típ 2. Đối tượng và phương pháp nghiên cứu: Nghiên cứu được thực hiện trên nhóm chứng gồm 115 đối tượng có glucose máu và mức lọc cầu thận bình thường; 137 bệnh nhân đái tháo đường típ 2. Không có tình trạng ảnh hưởng đến nồng độ Cystatin C huyết thanh ở cả 2 nhóm (rối loạn chức năng tuyến giáp, điều trị corticoid). Chẩn đoán ĐTĐ theo ADA 2015, giảm GFR theo KDIGO 2012. - Xét nghiệm Cystatin C huyết thanh thực hiện trên 2 nhóm. Đo xạ hình thận, ước đoán mức lọc cầu thận (GFR) bằng công thức CKD.EPI trên bệnh nhân ĐTĐ típ 2. Nghiên cứu được thực hiện theo phương pháp mô tả, cắt ngang. Phân tích các mối tương quan, hồi quy, tính diện tích dưới đường cong ROC cho nồng độ Cystatin C huyết thanh bằng SPSS. Kết quả: -Nồng độ Cystatin C huyết thanh ở bệnh nhân ĐTĐT2 là 1,37±0,87 mg/L cao hơn nhóm chứng 0,84±0,09 mg/L (p 〈 0,001). -Có mối tương quan thuận giữa GFR ước tính theo công thức CKD.EPI dựa vào Cystatin C huyết thanh với xạ hình thận, r = 0,818; p 〈 0,001. Có mối tương quan thuận giữa GFR ước tính theo công thức CKD.EPI dựa vào Creatinine-Cystatin C với xạ hình thận, r = 0,820; p 〈 0,001. - Cystatin C có độ nhạy, độ đặc hiệu, ROC rất cao trong dự đoángiảm GFR 〈 60ml/phút/1,73m2 theo xạ hình thận (93,94%; 87,5%; ROC 0,936; p 〈 0,001). - Tăng nồng độ Cystatin C là YTNC độc lập dự đoán giảm GFR 〈 60 ml/phút/1,73m2. Mô hình hồi quy binary logistic: Logistic (GFR 〈 60 ml/phút/1,73m2) = -7,968 + 3,841 x Cystatin C huyết thanh. Kết luận: Nồng độ Cystatin C huyết thanh ở bệnh nhân ĐTĐT2 cao hơn nhóm chứng. Có mối tương quan thuận giữa GFR ước tính dựa vào Cystatin C với xạ hình thận. Cystatin C có độ nhạy, độ đặc hiệu cao hơn creatinine trong chẩn đoán giảm GFR.Cystatin C là YTNC độc lập dự đoán giảm GFR 〈 60ml/phút/1,73m2.
    Type of Medium: Online Resource
    ISSN: 1859-4727
    URL: Issue
    URL: Article
    DOI: 10.47122/vjde.2020.41
    DOI: 10.47122/vjde.2020.41.12
    Language: Unknown
    Publisher: Vietnam Association of Diabetes and Endocrinology
    Publication Date: 2021
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  • 5
    Online Resource
    Online Resource
    CORRELATION BETWEEN SERUM CYSTATIN C LEVEL AND RENAL FUNCTION IN PREDIABETES, TYPE 2 DIABETIC PATIENTS
    Hue University of Medicine and Pharmacy ; 2017
    In:  Journal of Medicine and Pharmacy
    Details
    In: Journal of Medicine and Pharmacy, Hue University of Medicine and Pharmacy
    Abstract: Objectives: To investigate serum Cystatin C level, percentage of elevated serum cystatin C in prediabetic, type 2 diabetic patients. Relationship between serum Cystatin C levels and albuminuria in prediabetes. Correlation between serum Cystatin C levels and estimated glomerular filtration rate (eGFR), renal radiography in type 2 diabetic patients. Materials and methods: 90 healthy subjects, 60 patients with prediabetes, and 124 type 2 diabetic patients were inrolled into this study. We excluded patients with thyroid dysfunction and those taking glucocorticoids that affect the serum Cystatin level. The serum Cystatin C and Creatinine, renal radiography, albuminuria, and eGFR using CKD.EPI, MDRD formular were calculated. Descriptive and cross-sectional study. Analyzed correlation, Receiver operating characteristics (ROC), calculated the area under the curve (AUC) for serum Cystatin C. Results: The level of serum Cystatin C gradually significantly increased in healthy subjects, prediabetes, and type 2 diabetic patients (0.848±0.097; 0.894±0.113; 1.410±0.900 mg/L, p 〈 0.05, respectively). Percentage of elevated serum cystatin C in prediabetic and type 2 diabetic patients were 13%, 47.6%, p 〈 0.05, respectively. There was a positive correlation of serum cystatin C with albuminuria, a negatively correlation between serum Cystatin C level and eGFR in prediabetic subjects.There was a strong positively correlation of eGFR according to CKD.EPI equation based on serum Cystatin C (r=0.804, p 〈 0.001) and renal radiography (r=0.767, p 〈 0.001). The strong positively correlation between eGFR based on serum Creatinine-Cystatin C and renal radiography (r=0.804, p 〈 0.001). Serum Cystatin C level was significantly negatively correlation with eGFR based on cystatin C serum (r=-0.861, p 〈 0.001) and renal radiography (r=0.739 p 〈 0.001). The cut off value for the identification of GFR 〈 60ml/min/1.73m2 was 1.53mg/l with a sensitivity of 93.6 (95%CI: 78.3- 96.3) and specificity of 97.4 (95%CI: 88.0- 98.2), AUC was 0.96 according to renal radiography.The cutoff value for the identification of GFR 〈 60ml/min/1.73m2 was 1.3mg/l with a sensitivity of 100,0 (95%CI: 91.3- 100.0) and specificity of 94.0 (95%CI: 86.5- 98,0), AUC was 0,989 according to CKD.EPI formular based on Cystatin C. Conclusions: The level of serum Cystatin C gradually significantly increased in healthy subjects, prediabetes, and type 2 diabetic patients. There was a correlation of serum cystatin C with albuminuria, eGFR in prediabetic subjects. There was a positive correlation between eGFR based on Cystatin C and renal radiography. A negativelysignificantly correlation between serum Cystatin C level and eGFR,renal radiography. Serum Cystatin C had strong sensitivityand specificity for detecting reduced GFR. Key words: prediabetes, diabetes mellitus, glomerular filtration rate, Cystatin C, albuminuria
    Type of Medium: Online Resource
    ISSN: 1859-3836
    URL: Journal
    URL: Article
    DOI: 10.34071/jmp
    DOI: 10.34071/jmp.2017.5.23
    Language: Vietnamese
    Publisher: Hue University of Medicine and Pharmacy
    Publication Date: 2017
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  • 6
    Online Resource
    Online Resource
    STUDY OF RENAL FUNCTION IN TYPE 2 DIABETIC PATIENTS BY SERUM CYSTATIN C
    Hue University of Medicine and Pharmacy ; 2017
    In:  Journal of Medicine and Pharmacy
    Details
    In: Journal of Medicine and Pharmacy, Hue University of Medicine and Pharmacy
    Abstract: Aims: to investigate serum Cystatin C level, correlation between serum Cystatin C levels with albuminuria, estimate glomerular filtration rate (eGFR), and renal radiography in type 2 diabetic patients. Materials and methods: We studied 77 healthy subjects without prediabetes or diabetes, and 70 type 2 diabetic patients. We excluded patients with thyroid dysfunction and those taking glucocorticoids that affect the serum Cystatin level. The serum Cystatin C level measured in 2 groups. In type 2 diabetic patients, we measured renal radiography, albuminuria, and estimated GFR using CKD.EPI 2012 formular. Descriptive and cross-sectional study. A statistical analyses of the data was performed using SPSS, Excel 2003. Receiver operating characteristics (ROC) analysis, calculated the area under the curve (AUC) for serum Cystatin C. Results: The level of serum Cystatin C in the type 2 diabetic patients was significantly higher than in the control group (1.45±0.97, 0.97±0.23 mg/L, p 〈 0.001, respectively). The level of serum Cystatin C showed stepwise increase with albuminuria level. The serum cystatin C level in the macroalbuminuria group was significantly higher than microalbuminuria group (2,51±1,13; 1,12±0.69 mg//l, p 〈 0.05, respectively). A positively correlation was observed between eGFR according to CKD.EPI equation based on serum Cystatin C and renal radiography (r=0.710, p 〈 0.001). The positively correlation between eGFR according to CKD.EPI equation based on serum Creatinine-Cystatin C and renal radiography r=0.746, p 〈 0.001). The serum Cystatin C level was significantly higher in patients with GFR 〈 60 ml/min/1.73m2 than those with ≥ 60 ml/min/1.73m2 (p 〈 0,001). Serum Cystatin C level was significantly reciprocal correlation between eGFR based on cystatin C serum (r=0.830, p 〈 0.001) or renal radiography (r=0,748, p 〈 0,001). The cutoff value for the identification of GFR 〈 60ml/min/1.73m2 was 1.28mg/l with a sensitivity of 100.0 (95% CI: 85,6-100,0) and specificity of 95.7 (95%CI:85.1-99.3). AUC was 0,992. Conclusions: The serum cystatin C level in type 2 diabetic patients was significantly higher than the control group. The serum level of Cystatin C in type 2 diabetic patients was stepwise increased with albuminuria level. There was a positive correlation between eGFR based on Cystatin C and renal radiography. A reciprocal correlation between serum Cystatin C level and eGFR calculated by CKD.EPI 2012 formular and GFR by renal radiography. Key words: diabetes, glomerular filtration rate, Cystatin C, albuminuria
    Type of Medium: Online Resource
    ISSN: 1859-3836
    URL: Journal
    URL: Article
    DOI: 10.34071/jmp
    DOI: 10.34071/jmp.2016.6.7
    Language: Vietnamese
    Publisher: Hue University of Medicine and Pharmacy
    Publication Date: 2017
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  • 7
    Online Resource
    Online Resource
    Extracellular polymeric substances production in sludge by bacteria isolated from Hanoi brewery
    Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications) ; 2015
    In:  TAP CHI SINH HOC Vol. 36, No. 3 ( 2015-03-26)
    Details
    In: TAP CHI SINH HOC, Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications), Vol. 36, No. 3 ( 2015-03-26)
    Type of Medium: Online Resource
    ISSN: 0866-7160 , 0866-7160
    URL: Article
    DOI: 10.15625/0866-7160/v36n3.5996
    Language: Unknown
    Publisher: Publishing House for Science and Technology, Vietnam Academy of Science and Technology (Publications)
    Publication Date: 2015
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  • 8
    Online Resource
    Online Resource
    Feature Analysis for Imbalanced Learning
    Fuji Technology Press Ltd. ; 2020
    In:  Journal of Advanced Computational Intelligence and Intelligent Informatics Vol. 24, No. 5 ( 2020-09-20), p. 648-655
    Details
    In: Journal of Advanced Computational Intelligence and Intelligent Informatics, Fuji Technology Press Ltd., Vol. 24, No. 5 ( 2020-09-20), p. 648-655
    Abstract: Based on the results of artificial samples generated in the minority class and through the label regulation of the neighbor samples of the majority class, the precision of the classification prediction for imbalanced learning has clearly been enhanced. This article presents a unified solution combining learning factors to improve the learning performance. The proposed method solves this imbalance through a feature selection incorporating the generation of artificial samples and label regulation. A probabilistic representation is used for all aspects of learning: class, sample, and feature. A Bayesian inference is applied to the learning model to interpret the imbalance occurring in the training data and to describe solutions for recovering the balance. We show that the generation of artificial samples is sample based approach and label regulation is class based approach. We discovered that feature selection achieves surprisingly good results when combined with a sample- or class-based solution.
    Type of Medium: Online Resource
    ISSN: 1883-8014 , 1343-0130
    URL: Article
    DOI: 10.20965/jaciii.2020.p0648
    Language: English
    Publisher: Fuji Technology Press Ltd.
    Publication Date: 2020
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  • 9
    Online Resource
    Online Resource
    The Impact of Capital Investments on Firm Financial Performance – Empirical Evidence from the Listed Food and Agriculture Companies in Vietnam
    Agricultural University Press ; 2023
    In:  Vietnam Journal of Agricultural Sciences Vol. 6, No. 1 ( 2023-03-29), p. 1735-1744
    Details
    In: Vietnam Journal of Agricultural Sciences, Agricultural University Press, Vol. 6, No. 1 ( 2023-03-29), p. 1735-1744
    Abstract: Capital investment is one of the most important financial decisions of a firm, which effects the business survival. This paper investigates the impact of capital investments on firm performance to provide an insight for future capital investment decisions of companies. The study uses unbalance panel data gathered from 62 companies which covered 688 observations of listed food and agriculture sector in Vietnam stock exchange during the period 2009 – 2020. To control for unobserved individual effects, the random effect estimator was employed. Profit margin (PM) is used as a proxy for firm performance, while independent variables are capital investment rate in both short-term and long-term effect, equity to total assets ratio, firm size and tangible to fixed assets ratio. The results indicate that capital investments have statistically significant positive impact on long-term performance of the analyzed enterprises. This outcome is in accordant with many previous studies. Especially in the context of Vietnam listed food and agriculture companies have high level of capital investment, a portion increase in capital investment rate will increase the company profit margin. Other variables also have statistically significant relationship with profit margin, in details, equity ratio and size have positive effect while tangible assets ratio has negative effect on firm performance. Therefore, the research suggest firm managers should choose the appropriate capital investment strategies in long-term perspective, within the consideration of equity ratio, economics of scale and tangible assets investment ratio to get the most efficient performance.
    Type of Medium: Online Resource
    ISSN: 2588-1299 , 2588-1299
    URL: Article
    DOI: 10.31817/vjas.2023.6.1.04
    Language: Unknown
    Publisher: Agricultural University Press
    Publication Date: 2023
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  • 10
    Online Resource
    Online Resource
    Prevalence and Antimicrobial Susceptibility of Enterobacteriaceae Isolated from Retail Pepper in Vietnam
    Elsevier BV ; 2017
    In:  Journal of Food Protection Vol. 80, No. 5 ( 2017-05), p. 716-724
    Details
    In: Journal of Food Protection, Elsevier BV, Vol. 80, No. 5 ( 2017-05), p. 716-724
    Type of Medium: Online Resource
    ISSN: 0362-028X
    URL: Article
    DOI: 10.4315/0362-028X.JFP-16-501
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2017
    detail.hit.zdb_id: 2093078-1
    SSG: 21
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