In:
Beilstein Journal of Organic Chemistry, Beilstein Institut, Vol. 15 ( 2019-01-08), p. 72-78
Abstract:
The regioselective addition of Grignard reagents to mono- and disubstituted N -acylpyrazinium salts affording substituted 1,2-dihydropyrazines in modest to excellent yields (45–100%) is described. Under acidic conditions, these 1,2-dihydropyrazines can be converted to substituted Δ 5 -2-oxopiperazines providing a simple and efficient approach towards their preparation.
Type of Medium:
Online Resource
ISSN:
1860-5397
Language:
English
Publisher:
Beilstein Institut
Publication Date:
2019
detail.hit.zdb_id:
2192461-2
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