In:
Acta Cirurgica Brasileira, FapUNIFESP (SciELO), Vol. 13, No. 2 ( 1998-04), p. 80-85
Abstract:
Over the past 6 years we have used the Sangenstaken-Blackmore balloon to tamponade transfixing hepatic lesions. To replace this foreign body, we have considered the use of type I collagen, manufactured at Univ. Campinas, which can be molded to the entire wounded area, thus tamponading all surface irregularities. In this way, a complete tamponade may be achieved, and bile loss is prevented. Complete absorption of the material removes the problem of a foreign body. Twenty mongrel dogs received a perforating transfixing lesion in the central region of the liver, similar to that caused by a firearm bullet. Into the wounded tunnel type I collagen was introduced. Evaluations were made in the 4th, 7th, 15th and 30th day after the intervention, when animals were sacrificed. Polarizing microscope evaluation induced a homogeneous scar formation, with early, organized hepatic regeneration evident from the 7th day onward. It is therefore believed that the use of type I collagen is an effective and safe method to be used in this type of hepatic wounds.
Type of Medium:
Online Resource
ISSN:
0102-8650
DOI:
10.1590/S0102-86501998000200003
Language:
Unknown
Publisher:
FapUNIFESP (SciELO)
Publication Date:
1998
detail.hit.zdb_id:
2012156-8
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