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  • 1
    Online Resource
    Online Resource
    Severe hypocalcaemia in a COVID-19 female patient
    Bioscientifica ; 2021
    In:  Endocrinology, Diabetes & Metabolism Case Reports Vol. 2021 ( 2021-01-27)
    Details
    In: Endocrinology, Diabetes & Metabolism Case Reports, Bioscientifica, Vol. 2021 ( 2021-01-27)
    Abstract: Comorbidities are a risk factor for patients with COVID-19 and the mechanisms of disease remain unclear. The aim of this paper is to present a case report of an COVID-19 patient with severe hypocalcaemia. This is a report of an 81-year-old female, suffered from myalgia and fatigue for more than 3–4 weeks. Fever and cough appear 2 days before she presented to the emergency room. On physical examination, she was febrile with a temperature of 38.8°C, accompanied by cough, sore throat, headache, fatigue, and muscle ache. Her past medical history was remarkable with no chronic disease. She had lymphopenia. Laboratory test revealed moderate liver dysfunction, hypoalbuminemia, and severe hypocalcaemia (serum corrected calcium level: 5.7  mg/dL). Parathyroid hormone (PTH) was 107.9 pg/mL (range: 15–65) and 25(OH)2D levels was 4.5 ng/mL (range: 25–80). Chest CT scan detected peripheral ground-glass opacity. Throat swab for coronavirus by RT-PCR assay tested positive for the virus. She was treated with lopinavir/ritonavir, third generation cephalosporin, anticoagulant, daily high-dose calcium acetate, vitamin D 3 , fresh frozen plasma and oxygen therapy. She was discharged after two negative throat swab tests for coronavirus by conventional RT-PCR. Learning points: Comorbidities are a risk factor for patients with COVID-19. Laboratory findings are unspecific in COVID-19 patients; laboratory abnormalities include lymphopenia, elevated of LDH, CPK and the inflammatory markers, such as C reactive protein, ferritinemia and the erythrocyte sedimentation rate. In addition to inflammatory markers, in COVID-19 patients it is crucial to check the level of vitamin D and calcium. There may be a correlation between vitamin D deficiency and the severity of COVID-19 disease.
    Type of Medium: Online Resource
    ISSN: 2052-0573
    URL: Article
    DOI: 10.1530/EDM-20-0097
    Language: Unknown
    Publisher: Bioscientifica
    Publication Date: 2021
    detail.hit.zdb_id: 2785530-2
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  • 2
    Online Resource
    Online Resource
    Epidemiological, clinical and therapeutic aspects of cerebral malaria imported in Albania
    Journal of Infection in Developing Countries ; 2016
    In:  The Journal of Infection in Developing Countries Vol. 10, No. 02 ( 2016-02-28), p. 190-194
    Details
    In: The Journal of Infection in Developing Countries, Journal of Infection in Developing Countries, Vol. 10, No. 02 ( 2016-02-28), p. 190-194
    Abstract: This is a case-report of two patients with cerebral malaria (CM) imported from West-African countries. Notably, this form of malaria was developed as a second disease episode, while the first episode was experienced in West Africa. These findings suggest that the second episode of malaria was caused by a different strain of Plasmodium falciparum as compared to the first one. They are the first cerebral malaria cases imported in Albania after the eradication and absence of Plasmodium for five decades. Early treatment of cerebral malaria is decisive on the duration of coma and disease’s outcome.
    Type of Medium: Online Resource
    ISSN: 1972-2680
    URL: Article
    DOI: 10.3855/jidc.6321
    Language: Unknown
    Publisher: Journal of Infection in Developing Countries
    Publication Date: 2016
    detail.hit.zdb_id: 2394024-4
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  • 3
    Online Resource
    Online Resource
    Is acute Appendicitis as an extra Pulmonary Manifestation of Covid-19 infection?
    Albanian Society for Trauma and Emergency Surgery ; 2022
    In:  Albanian Journal of Trauma and Emergency Surgery Vol. 6, No. 2 ( 2022-07-20), p. 1069-1072
    Details
    In: Albanian Journal of Trauma and Emergency Surgery, Albanian Society for Trauma and Emergency Surgery, Vol. 6, No. 2 ( 2022-07-20), p. 1069-1072
    Abstract: Background; Coronavirus disease-19 (COVID-19) is an infectious respiratory disease. The first confirmed case of 2019-nCoV infection in Albania was reported in Tirana on 08 March 2020, when a patient and his adult son who had come from Florence, Italy tested positive. Patients with COVID-19 can be presented with a series of signs and symptoms. Acute abdomen as a presentation of COVID-19 is rare. The diagnosis of COVID-19 should be suspected and investigated in every case of acute abdomen. Case presentation: We report a case of a 42-year-old male who presented with features of acute appendicitis. SARS-CoV-2 polymerase chain reaction test result was positive for COVID-19. Abdominal ultrasonography and his computed tomography of the chest and abdomen showed a perforated appendix and no infiltrates or abnormalities of COVID-19. The diagnosis of our case was appendicitis with COVID-19 without pneumonia. He was admitted and treated with antibiotic therapy and supportive care. He had an improvement in his health condition which made it possible to leave the hospital on the third day of hospitalization. Conclusion: Based on our clinical case and literature data, we suggest that clinicians should suspect the diagnosis of acute appendicitis in patients with COVID 19. So the case of acute abdomen pain must be completed with a SARS-CoV-2 test. Therefore we recommend additional studies to reinforce the idea of ​​linking SARS COV 2 infection with acute appendicitis.
    Type of Medium: Online Resource
    ISSN: 2616-4922 , 2521-8778
    URL: Issue
    URL: Article
    DOI: 10.32391/ajtes.v6i2
    DOI: 10.32391/ajtes.v6i2.278
    Language: Unknown
    Publisher: Albanian Society for Trauma and Emergency Surgery
    Publication Date: 2022
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  • 4
    Online Resource
    Online Resource
    Severity and Mortality Predictors of COVID-19 Patients with Thrombotic Events-Evidence from the “COVID-One” Hospital in Albania
    MDPI AG ; 2022
    In:  Vaccines Vol. 10, No. 11 ( 2022-10-31), p. 1851-
    Details
    In: Vaccines, MDPI AG, Vol. 10, No. 11 ( 2022-10-31), p. 1851-
    Abstract: COVID-19 vaccination leads to lower infection, morbidity, and mortality rates. However, COVID-19 infection leads to the development of coagulopathy-related manifestations in the form of both venous and arterial thromboembolism. This study aimed to assess the severity and mortality predictors of COVID-19 patients with thrombotic events in hospitalized patients in Albania. This is a retrospective study conducted in the “Mother Tereza” University Hospital of Tirana. Data were retrieved from the electronic databases of the hospital and only COVID-19 cases admitted to the infectious department during August–December 2020 were selected. Patients who, at admission, had a C-reactive protein (CRP) (mg/L) more than double and a D-dimer (ng/mL) more than triple according to international standards were included in the study. We performed univariate and multivariable logistic regression analysis, calculating unadjusted and adjusted odds ratios (ORs). A p-value 〈 0.05 was considered statistically significant. The study population included 60 hospitalized persons with a mean age of 64.4 years. Increased lactate dehydrogenase (LDH) (OR = 2.93; 95% CI = 0.82–10.42, p-value = 0.1) and increased creatine kinase (CK) (OR = 2.17; 95% CI = 0.63–7.46, p-value = 0.22) were related with increased probability of death. Moreover, a decreased number of lymphocytes was associated with increased mortality but with no statistical significance (OR = 0.40; 95% CI = 0.11–1.40, p-value = 0.15). The survival rate was higher for patients without comorbidities (p = 0.045). These results could serve as a baseline and as a reference for healthcare personnel who provides services to hospitalized patients with COVID-19. Further studies should take into consideration the vaccination of the population as well as including more hospitals and patients.
    Type of Medium: Online Resource
    ISSN: 2076-393X
    URL: Article
    DOI: 10.3390/vaccines10111851
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2703319-3
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  • 5
    Online Resource
    Online Resource
    Portraying infective endocarditis: results of multinational ID-IRI study
    Springer Science and Business Media LLC ; 2019
    In:  European Journal of Clinical Microbiology & Infectious Diseases Vol. 38, No. 9 ( 2019-9), p. 1753-1763
    Details
    In: European Journal of Clinical Microbiology & Infectious Diseases, Springer Science and Business Media LLC, Vol. 38, No. 9 ( 2019-9), p. 1753-1763
    Type of Medium: Online Resource
    ISSN: 0934-9723 , 1435-4373
    URL: Article
    DOI: 10.1007/s10096-019-03607-x
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2019
    detail.hit.zdb_id: 1459049-9
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  • 6
    Online Resource
    Online Resource
    Febrile Syndrome in HIV positive patients
    European University of Tirana ; 2020
    In:  Medicus Vol. 4, No. 1 ( 2020), p. 70-76
    Details
    In: Medicus, European University of Tirana, Vol. 4, No. 1 ( 2020), p. 70-76
    Abstract: Fever is one of the accompanying symptoms of HIV, mainly in the advanced stages of the disease, but its occurrence is related to a number of factors such as CD4+ Lymphocyte level, accompanying opportunistic infections; causative microorganisms etc. Fever accompanies HIV from the initial stage of the “acute retroviral syndrome” infection and during the evolution of the pathology towards the AIDS stage, even in IRIS. Fever-related opportunistic infections are divided into two groups by infectious or non-infectious causes3,4. In our study, we included 355 HIV-positive cases who had febrile episodes in different stages of immunodeficiency. In the HIV stage (to which we referred lymphocytes CD4+ over 500 cells/mm3, and without AIDS-related opportunistic infections) there were 39 cases. In the AIDS stage, there were 143 cases with a CD4 + level of 200-400 cells/mm3: pulmonary manifestations 85 cases, gastrointestinal 58 cases. With a level of CD4+ lymphocytes below 200 cells/ mm3 123 cases; pulmonary involvement 45 cases, intestinal 32 cases, CNS 11 cases, hematological.13 cases, disseminated 15 cases, FUO 7 cases. With CD4+ level below 50 cells mm3, 50 cases: non-Hodgkin’s lymphoma 9 cases. MAC 3 cases, TBC.19 cases, CNS lymphoma. 6 cases, retinal CMV 3 cases, Kaposi’s sarcoma 10 cases.
    Type of Medium: Online Resource
    ISSN: 2663-7758 , 2958-8871
    URL: Journal
    URL: Article
    DOI: 10.58944/bwhm8602
    DOI: 10.58944/vthx4596
    Language: Unknown
    Publisher: European University of Tirana
    Publication Date: 2020
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  • 7
    Online Resource
    Online Resource
    Risk factors for poor outcome of patients with Coronavirus disease 2019 (COVID-19) in Albania
    Journal of Infection in Developing Countries ; 2021
    In:  The Journal of Infection in Developing Countries Vol. 15, No. 09 ( 2021-09-30), p. 1236-1243
    Details
    In: The Journal of Infection in Developing Countries, Journal of Infection in Developing Countries, Vol. 15, No. 09 ( 2021-09-30), p. 1236-1243
    Abstract: Introduction: The study aims to identify potential risk factors for the poor outcome of hospitalized patients with SARS-CoV-2 infection in Albania. Methodology: A retrospective observational study on 133 consecutive hospitalized patients at “COVID 1” Hospital, University Hospital Center of Tirana. The study analyzed the correlation between potential risk factors and in-hospital mortality. Results: The study included 133 patients, 65.4% of the patients were male, age 60.46 ± 13.53 years. The mortality rate resulted in 22.6%. Univariate analysis revealed that early risk factors for mortality included: laboratory alterations on admission, such as lymphocytes count 〈 1.000/mm3 (OR = 3.30, 95% CI = 1.17-9.33), lactate dehydrogenase 〉 250 U/L (OR = 12.48, 95% CI = 1.62-95.78) and D dimer 〉 2 mg/L (OR = 4.72, 95% CI = 1.96-11.36); lung parenchymal involvement 〉 75% on chest computed tomography on admission (OR = 54.00, 95% CI = 11.89 – 245.11). Cox proportional hazard regression showed that independent risk factors for mortality were lung parenchymal involvement 〉 75% on chest computed tomography (HR = 8.31, 95%CI: 1.62-42.45) and occurrence of complications during hospital stay (OR = 10.28, 95% CI = 2.02-52.33). Conclusions: The risk of poor outcome can be predicted from the early stage of COVID 19 disease, using laboratory data and chest computed tomography. Among patients with COVID 19, lung parenchymal involvement and alterations 〉 75% on chest computed tomography on admission and laboratory findings, such as lymphocytopenia, and elevated lactate dehydrogenase and D dimer levels, turned out to be early risk factors for in-hospital mortality.
    Type of Medium: Online Resource
    ISSN: 1972-2680
    URL: Article
    DOI: 10.3855/jidc.14592
    Language: Unknown
    Publisher: Journal of Infection in Developing Countries
    Publication Date: 2021
    detail.hit.zdb_id: 2394024-4
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  • 8
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    Online Resource
    A case report of urinary tract infection from Pseudoglutamicibacter cumminsii in an immunosuppressed patient
    Elsevier BV ; 2023
    In:  New Microbes and New Infections Vol. 53 ( 2023-06), p. 101133-
    Details
    In: New Microbes and New Infections, Elsevier BV, Vol. 53 ( 2023-06), p. 101133-
    Type of Medium: Online Resource
    ISSN: 2052-2975
    URL: Article
    DOI: 10.1016/j.nmni.2023.101133
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 2750179-6
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  • 9
    Online Resource
    Online Resource
    Clinical Response to Treatment of Infectious Rachiditis
    OMICS Publishing Group ; 2018
    In:  Journal of Infectious Diseases & Therapy Vol. 06, No. 05 ( 2018)
    Details
    In: Journal of Infectious Diseases & Therapy, OMICS Publishing Group, Vol. 06, No. 05 ( 2018)
    Type of Medium: Online Resource
    ISSN: 2332-0877
    URL: Journal
    URL: Article
    DOI: 10.4172/2332-0877
    DOI: 10.4172/2332-0877.1000375
    Language: Unknown
    Publisher: OMICS Publishing Group
    Publication Date: 2018
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  • 10
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    Online Resource
    Clinical Findings in Albanian Patients with 2009 Influenza AH1N1 Admitted at the Intensive Care Unit
    Hindawi Limited ; 2013
    In:  ISRN Emergency Medicine Vol. 2013 ( 2013-05-08), p. 1-6
    Details
    In: ISRN Emergency Medicine, Hindawi Limited, Vol. 2013 ( 2013-05-08), p. 1-6
    Abstract: Due to the ease of cross-continent spread of infectious diseases, the 2009 influenza AH1N1 (H1N1) affected many countries. This observational prospective study looked at Albanian patients admitted with 2009 H1N1 at the ICU of the Department of Infectious Diseases at the University Hospital Center of Tirana, from November 2009 to March 2010. Demographic data, symptoms, comorbidities, and clinical outcomes were collected from each patient. The number of days spent in the ICU was recorded for each patient along with their radiological and laboratory findings, and outcome at discharge. Critical illness occurred in 31 patients admitted with confirmed 2009 H1N1. The median age of patients was 35 years. Five (16.1%) patients required endotracheal intubation; noninvasive oxygen therapy (NIV) was used in 15 (48.4%) patients via nasal tube; and continuous positive airway pressure (CPAP) and pressure support ventilation (PSV) oxygen masks were used in 11 (35.5%) patients. All patients were treated with oseltamivir. Four patients admitted and treated did not survive. Critical illness in the setting of 2009 H1N1 admitted in the ICU predominantly affected young adults. NIV could play a role in treating 2009 influenza H1N1 infection-related hypoxemic respiratory failure that was associated with severe hypoxemia, pneumonia, requirement for prolonged mechanical ventilation, and the frequent use of antiviral therapy.
    Type of Medium: Online Resource
    ISSN: 2090-5637
    URL: Article
    DOI: 10.1155/2013/914840
    Language: English
    Publisher: Hindawi Limited
    Publication Date: 2013
    detail.hit.zdb_id: 2669067-6
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