In:
Stroke, Ovid Technologies (Wolters Kluwer Health), Vol. 6, No. 6 ( 1975-11), p. 707-714
Abstract:
Lactate and pyruvate concentrations and acid-base balance in cerebrospinal fluid (CSF) and arterial blood were determined in patients with intracranial hemorrhages (28 subarachnoid hemorrhages and 15 intracerebral hemorrhages). A greater increase in CSF lactate and lactate-pyruvate ratio (L/P ratio) was observed in patients with impairment of consciousness, focal neurological deficits, poor prognosis, or CSF pressures higher than 300 mm H 2 O. A combination of CSF lactate greater than 2.5 mM per liter, L/P ratio above 20, bicarbonate less than 20.4 mEq per liter, pH below 7.276, or arterial PCO 2 below 31.5 mm Hg seems to indicate a poor prognosis from intracranial hemorrhage. The mechanism of hyperventilation in acute cerebrovascular diseases and of CSF pH regulation in acid-base disturbances was also discussed.
Type of Medium:
Online Resource
ISSN:
0039-2499
,
1524-4628
DOI:
10.1161/01.STR.6.6.707
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
1975
detail.hit.zdb_id:
1467823-8
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