In:
Journal of Magnetic Resonance Imaging, Wiley, Vol. 57, No. 5 ( 2023-05), p. 1492-1504
Abstract:
The myocardial kinetic energy ( KE ) and its association with pulmonary regurgitation ( PR ) have yet to be investigated in repaired tetralogy of Fallot ( rTOF ) patients. Purpose To evaluate the adaptation of myocardial KE in rTOF patients by tissue phase mapping (TPM). Study Type Prospective. Population A total of 49 rTOF patients (23 ± 5 years old; male = 32), 47 normal controls (22 ± 1 year old; male = 29). Field Strength/Sequence 3‐T/2D dark‐blood three‐directional velocity‐encoded gradient‐echo sequence. Assessment Left and right ventricle ( LV , RV ) myocardial KE in radial ( KE r ), circumferential ( KE ø ), longitudinal ( KE z ) directions. The proportions of KE in each direction to the sum of all KE ( KE røz ): % KE r , % KE ø , % KE z . PR fraction. Statistical Test Student's t test, multivariable regression. Statistical significance: P 〈 0.05. Results In rTOF group, LV KE z remained normal in systole ( P = 0.565) and diastole ( P = 0.210), whereas diastolic LV %KE z (62% ± 14% vs. 72% ± 7%) and systolic LV %KE ø (9% ± 6% vs. 20% ± 7%) were significantly decreased. The KE r and %KE r of both ventricles significantly increased in the rTOF group (RV in diastole: 6 ± 3 vs. 3 ± 1 μJ and 54% ± 13% vs. 27% ± 7%). The rTOF group exhibited significantly higher RV/LV ratios of %KE r (systole: 1.3 ± 0.3 vs. 1.0 ± 0.3) and %KE ø (systole: 1.6 ± 0.8 vs. 1.0 ± 0.3) and significantly lower ratios of %KE z in systole (0.7 ± 0.2 vs. 1.0 ± 0.1) and diastole (0.5 ± 0.2 vs. 0.9 ± 0.1). In multivariable regression analysis, the RV peak systolic KE røz , RV systolic KE z , and LV diastolic %KE ø were independently associated with PR fraction in the rTOF group (adjusted R 2 = 0.479). Data Conclusion In rTOF patients, the adaptation of the KE proportion occurred earlier than that of the KE amplitude, and the biventricular balance of %KE was disrupted. PR may cause differential KE adaptation in RV and LV. TPM‐derived KE may be useful in investigation of myocardial adaptation in rTOF patients. Evidence Level 2 Technical Efficacy Stage 3
Type of Medium:
Online Resource
ISSN:
1053-1807
,
1522-2586
Language:
English
Publisher:
Wiley
Publication Date:
2023
detail.hit.zdb_id:
1146614-5
detail.hit.zdb_id:
1497154-9
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