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  • 1
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    Online Resource
    Infrared thermography in the evaluation of meibomian gland dysfunction
    Elsevier BV ; 2017
    In:  Journal of the Formosan Medical Association Vol. 116, No. 7 ( 2017-07), p. 554-559
    Details
    In: Journal of the Formosan Medical Association, Elsevier BV, Vol. 116, No. 7 ( 2017-07), p. 554-559
    Type of Medium: Online Resource
    ISSN: 0929-6646
    URL: Article
    DOI: 10.1016/j.jfma.2016.09.012
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2017
    detail.hit.zdb_id: 2250901-X
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  • 2
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    Factors of missed appointments at an academic medical center in Taiwan
    Ovid Technologies (Wolters Kluwer Health) ; 2019
    In:  Journal of the Chinese Medical Association Vol. 82, No. 5 ( 2019-05), p. 436-442
    Details
    In: Journal of the Chinese Medical Association, Ovid Technologies (Wolters Kluwer Health), Vol. 82, No. 5 ( 2019-05), p. 436-442
    Type of Medium: Online Resource
    ISSN: 1726-4901
    URL: Article
    DOI: 10.1097/JCMA.0000000000000068
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2019
    detail.hit.zdb_id: 2202774-9
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  • 3
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    Varied impacts on outpatient services among departments and divisions in the early phase of the COVID-19 pandemic: Implications for personnel mobilization and preparatory training
    Ovid Technologies (Wolters Kluwer Health) ; 2021
    In:  Journal of the Chinese Medical Association Vol. 84, No. 10 ( 2021-10), p. 951-955
    Details
    In: Journal of the Chinese Medical Association, Ovid Technologies (Wolters Kluwer Health), Vol. 84, No. 10 ( 2021-10), p. 951-955
    Abstract: Coronavirus disease 2019 (COVID-19) spread all over the world in 2020. In the face of the sudden pandemic, workforce mobilization has been of critical concern to medical institutions. During the pandemic, the public’s behaviors of seeking medical assistance have also changed. Using the real-world data of a large medical center in Taiwan, this study aimed to analyze the fluctuations of outpatient visits among various departments and divisions in the early phase of the COVID-19 pandemic and to provide suggestions for staff allocation in similar future events. Methods: Data of outpatient visits at Taipei Veterans General Hospital were obtained for analysis. The weekly fluctuations of outpatient visits among 36 departments or divisions were computed for 8 weeks from February 3 to March 29, 2020, the early phase of the pandemic. The monthly data of outpatient visits by department and division in March 2020 were also extracted for comparison with those in March 2019. A simple regression equation was used to calculate the weekly trends. Results: Average outpatient visits decreased by 26% in 2 months following the outbreak. Among the 36 departments or divisions, ophthalmology, orthopedics, and cardiology underwent marked declines after the outbreak; the slopes of the simple regression equation were −110.8, −100.7, and −99.2, respectively. By contrast, transfusion medicine, toxicology, transplantation surgery, pediatric surgery, chest surgery, technical aid, and oncology were divisions less influenced. In the year-over-year comparison, infection was the only department or division with positive growth (20.5%), whereas all others exhibited negative growth. Conclusion: In the future, we can fulfil the additional personnel needs during a pandemic by redeploying physicians from departments experiencing a reduced workload. Hospitals should also establish preparatory employee training programs to ensure that the reassigned personnel are adequately equipped to serve in their new positions.
    Type of Medium: Online Resource
    ISSN: 1726-4901
    URL: Article
    DOI: 10.1097/JCMA.0000000000000569
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2021
    detail.hit.zdb_id: 2202774-9
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  • 4
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    A comparison of insulin suppression tests performed with somatostatin and octreotide with particular reference to tolerability
    Elsevier BV ; 2001
    In:  Diabetes Research and Clinical Practice Vol. 51, No. 3 ( 2001-3), p. 187-193
    Details
    In: Diabetes Research and Clinical Practice, Elsevier BV, Vol. 51, No. 3 ( 2001-3), p. 187-193
    Type of Medium: Online Resource
    ISSN: 0168-8227
    URL: Article
    DOI: 10.1016/S0168-8227(00)00238-2
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2001
    detail.hit.zdb_id: 2004910-9
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  • 5
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    Association of Apolipoprotein J Polymorphism 1598delT with Coronary Artery Disease and Lipoprotein Levels
    S. Karger AG ; 2011
    In:  Cardiology Vol. 118, No. 2 ( 2011), p. 83-92
    Details
    In: Cardiology, S. Karger AG, Vol. 118, No. 2 ( 2011), p. 83-92
    Abstract: 〈 i 〉 Objectives: 〈 /i 〉 To investigate a polymorphism of the apolipoprotein J 〈 i 〉 (APOJ) 〈 /i 〉 gene in relation to coronary artery disease (CAD) and lipid variables in a Chinese male population of genetically unrelated individuals. 〈 i 〉 Methods: 〈 /i 〉 In this study, we recruited 126 control male subjects and 237 CAD male patients. CAD was defined as a fixed stenotic lesion with luminal narrowing ≧50% in at least one of the major or minor coronary arteries. In cases with documented myocardial infarction, only those rated as fully recovered for more than 3 months were enrolled. Patients with acute or chronic infectious diseases and those with malignancies were excluded. All subjects with a fasting serum triglyceride level higher than 300 mg/dl were likewise excluded. 〈 i 〉 Results: 〈 /i 〉 We identified a single nucleotide polymorphism, 1598delT, and showed its association with CAD. Subjects with the I/I genotype showed a significantly higher CAD risk compared to those with the D/D genotype (OR 2.34, 95% CI 1.11–4.94, p = 0.026). Patients with the I/I genotype also had abnormal levels of high-density lipoprotein-cholesterol and low-density lipoprotein-cholesterol associated with CAD. 〈 i 〉 Conclusions: 〈 /i 〉 Our data indicated that the 〈 i 〉 APOJ 〈 /i 〉 single nucleotide polymorphism (1598delT) is associated with risk factors for CAD in a Chinese population.
    Type of Medium: Online Resource
    ISSN: 0008-6312 , 1421-9751
    URL: Article
    DOI: 10.1159/000326852
    RVK:
    XA 36200
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2011
    detail.hit.zdb_id: 1482041-9
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  • 6
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    Baicalein Reduces Liver Injury Induced by Myocardial Ischemia and Reperfusion
    World Scientific Pub Co Pte Ltd ; 2016
    In:  The American Journal of Chinese Medicine Vol. 44, No. 03 ( 2016-01), p. 531-550
    Details
    In: The American Journal of Chinese Medicine, World Scientific Pub Co Pte Ltd, Vol. 44, No. 03 ( 2016-01), p. 531-550
    Abstract: Baicalein is a component of the root of Scutellaria baicalensis Georgi, which has traditionally been used to treat liver disease in China. In the present study, we investigated baicalein’ ability to reduce the liver injury induced by myocardial ischemia and reperfusion (I/R). Myocardial I/R was induced in this experiment by a 40[Formula: see text]min occlusion of the left anterior descending coronary artery and a 3[Formula: see text] h reperfusion in rats. The induced myocardial I/R significantly increased the serum levels of aspartate transaminase (AST) and alanine transaminase (ALT), indicating the presence of liver injury. Hepatic apoptosis was significantly increased. The serum levels of tumor necrosis factor-[Formula: see text] (TNF-[Formula: see text] ), interleukin-1[Formula: see text] (IL-1[Formula: see text] ), and interleukin-6 (IL-6) were significantly elevated, as was the TNF-[Formula: see text] level in the liver. Intravenous pretreatment with baicalein (3, 10, or 30[Formula: see text] mg/kg) 10[Formula: see text]min before myocardial I/R significantly reduced the serum level increase of AST and ALT, apoptosis in the liver, and the elevation of TNF-[Formula: see text] , IL-1[Formula: see text], and IL-6 levels. Moreover, baicalein increased Bcl-2 and decreased Bax in the liver. Phosphorylation of the prosurvival kinases, including Akt and extracellular signal-regulated kinases 1 and 2 (ERK1/2), was also increased. In conclusion, we found that baicalein can reduce the liver injury induced by myocardial I/R. The underlying mechanisms are likely related to the inhibition of the extrinsic and intrinsic apoptotic pathways, possibly via the inhibition of TNF-[Formula: see text] production, the modulation of Bcl-2 and Bax, and the activation of Akt and ERK1/2. Our findings may provide a rationale for the application of baicalein or traditional Chinese medicine containing large amounts of baicalein to prevent liver injury in acute myocardial infarction and cardiac surgery.
    Type of Medium: Online Resource
    ISSN: 0192-415X , 1793-6853
    URL: Article
    DOI: 10.1142/S0192415X16500294
    Language: English
    Publisher: World Scientific Pub Co Pte Ltd
    Publication Date: 2016
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  • 7
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    Baicalein Attenuates Lung Injury Induced by Myocardial Ischemia and Reperfusion
    World Scientific Pub Co Pte Ltd ; 2017
    In:  The American Journal of Chinese Medicine Vol. 45, No. 04 ( 2017-01), p. 791-811
    Details
    In: The American Journal of Chinese Medicine, World Scientific Pub Co Pte Ltd, Vol. 45, No. 04 ( 2017-01), p. 791-811
    Abstract: Baicalein is an active component of Scutellaria baicalensis Georgi, which has traditionally been used to treat cardiovascular diseases in China. In this study, we investigated if treatment with baicalein can attenuate the lung injury induced by myocardial ischemia and reperfusion (I/R). Myocardial I/R, induced by a 40-min occlusion of the left anterior descending coronary artery and a 3-h reperfusion, significantly increased histological damage and the wet-to-dry weight ratio of lungs in rats. The terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL)-positive nuclei and caspase-3 activation was significantly increased in the lungs. Serum and bronchoalveolar lavage fluid levels of tumor necrosis factor-[Formula: see text] (TNF-[Formula: see text] ), interleukin-1[Formula: see text] (IL-1[Formula: see text] ), and interleukin-6 (IL-6) were significantly elevated, as were TNF-[Formula: see text] levels in the lung. Intravenous administration with baicalein at doses of 3, 10, and 30[Formula: see text] mg/kg for ten minutes before myocardial I/R significantly reduced histological damage, the wet-to-dry weight ratio, and apoptosis in the lung. Baicalein also significantly inhibited the increase in levels of TNF-[Formula: see text], IL-1[Formula: see text] , and IL-6. Moreover, baicalein increased Bcl-2 and decreased p53, Bax, and cytochrome [Formula: see text] in lungs. Phosphorylation of the prosurvival kinases, including Akt and extracellular signal-regulated kinases 1 and 2 (ERK1/2), was increased, while the phosphorylation of the pro-apoptotic mitogen-activated protein kinases, including p38 and c-Jun N-terminal kinase (JNK), was decreased. In conclusion, treatment with baicalein attenuates the lung injury induced by myocardial I/R. The mechanisms might be related to the limiting of apoptosis, possibly via the inhibition of both the extrinsic and intrinsic pathways of apoptosis, including the inhibition of TNF-[Formula: see text] production and modulation of pro- and anti-apoptotic signaling elements.
    Type of Medium: Online Resource
    ISSN: 0192-415X , 1793-6853
    URL: Article
    DOI: 10.1142/S0192415X17500422
    Language: English
    Publisher: World Scientific Pub Co Pte Ltd
    Publication Date: 2017
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  • 8
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    Magnolol Reduces Renal Ischemia and Reperfusion Injury via Inhibition of Apoptosis
    World Scientific Pub Co Pte Ltd ; 2017
    In:  The American Journal of Chinese Medicine Vol. 45, No. 07 ( 2017-01), p. 1421-1439
    Details
    In: The American Journal of Chinese Medicine, World Scientific Pub Co Pte Ltd, Vol. 45, No. 07 ( 2017-01), p. 1421-1439
    Abstract: Magnolol, a constituent of the bark of Magnolia officinalis, has been reported to decrease myocardial stunning and infarct size. In this study, we investigated whether magnolol can reduce renal ischemia and reperfusion (I/R) injury. Renal I/R, induced by a 60-min occlusion of bilateral renal arteries and a 24-h reperfusion, significantly increased blood urea nitrogen (BUN) and creatinine levels, and caused histological damage to the kidneys of rats. Apoptosis, as evaluated by terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) staining and caspase-3 activation, was significantly increased in the kidneys. Furthermore, serum levels of tumor necrosis factor-[Formula: see text] (TNF-[Formula: see text] ), interleukin-1β (IL-1β), and interleukin-6 (IL-6) were significantly elevated, while the interleukin-10 (IL-10) level was suppressed. However, intravenous pretreatment with magnolol at doses of 0.003[Formula: see text]mg/kg and 0.006[Formula: see text] mg/kg 10[Formula: see text]min before renal I/R significantly limited the increases of BUN, creatinine, the histological damage, and apoptosis in the kidneys. The increases in TNF-[Formula: see text] , IL-1β, and IL-6, and the decrease in IL-10 were also significantly inhibited. Additionally, magnolol increased Bcl-2 and decreased Bax in the kidneys. Phosphorylation of the prosurvival kinases, including Akt and extracellular signal-regulated kinases 1 and 2 (ERK1/2), was elevated, while phosphorylation of the pro-apoptotic mitogen-activated protein kinases, including p38 and c-Jun N-terminal kinase (JNK), was suppressed. In conclusion, magnolol reduces renal I/R injury. The underlying mechanisms for this effect might be related to the prevention of apoptosis, possibly via the inhibition of both extrinsic and intrinsic apoptotic pathways, including the reduction of TNF-[Formula: see text] production and the modulation of pro- and anti-apoptotic signaling elements.
    Type of Medium: Online Resource
    ISSN: 0192-415X , 1793-6853
    URL: Article
    DOI: 10.1142/S0192415X1750077X
    Language: English
    Publisher: World Scientific Pub Co Pte Ltd
    Publication Date: 2017
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  • 9
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    OnabotulinumtoxinA Improves Tactile and Mechanical Pain Perception in Painful Diabetic Polyneuropathy
    Ovid Technologies (Wolters Kluwer Health) ; 2013
    In:  The Clinical Journal of Pain Vol. 29, No. 4 ( 2013-04), p. 305-310
    Details
    In: The Clinical Journal of Pain, Ovid Technologies (Wolters Kluwer Health), Vol. 29, No. 4 ( 2013-04), p. 305-310
    Type of Medium: Online Resource
    ISSN: 0749-8047
    URL: Article
    DOI: 10.1097/AJP.0b013e318255c132
    RVK:
    XA 10000
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2013
    detail.hit.zdb_id: 1497640-7
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  • 10
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    Disparity of physician specialties in the management of chronic heart failure: trend analysis in Taiwan, 2000 2010
    Dustri-Verlgag Dr. Karl Feistle ; 2013
    In:  Int. Journal of Clinical Pharmacology and Therapeutics Vol. 51, No. 08 ( 2013-08-01), p. 678-687
    Details
    In: Int. Journal of Clinical Pharmacology and Therapeutics, Dustri-Verlgag Dr. Karl Feistle, Vol. 51, No. 08 ( 2013-08-01), p. 678-687
    Type of Medium: Online Resource
    ISSN: 0946-1965
    URL: Article
    DOI: 10.5414/CP201762
    Language: English
    Publisher: Dustri-Verlgag Dr. Karl Feistle
    Publication Date: 2013
    SSG: 12
    SSG: 15,3
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