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  • 1
    Online Resource
    Online Resource
    The risk of chronic kidney disease among women with polycystic ovary syndrome: A long‐term population‐based cohort study
    Wiley ; 2020
    In:  Clinical Endocrinology Vol. 93, No. 5 ( 2020-11), p. 590-597
    Details
    In: Clinical Endocrinology, Wiley, Vol. 93, No. 5 ( 2020-11), p. 590-597
    Abstract: Results of studies focusing on chronic kidney disease (CKD) among women with polycystic ovary syndrome (PCOS) are insufficient and controversial. This study aimed to evaluate the incidence rate of CKD in women with PCOS, compared to a control group of healthy women. Methods This study was a population‐based cohort study conducted from among 1460 reproductive‐age women including 156 women with PCOS and 1304 controls. Incidence rates per 1000 person‐years of follow‐up were calculated for PCOS and control groups. Cox proportional hazards regression with age as the time‐scale was used to estimate hazard ratios (HR) and 95% confidence intervals for developing CKD in relation to PCOS in both univariable and multivariable models. Results During a median follow‐up of 12.9 years, 330 new cases of CKD were identified, including 25 PCOS women (14.8 per 1000 person‐years; 95% CI, 10‐22) and 305 healthy controls (21.5 per 1000 person‐years; 95% CI, 19.2‐24.1). The results of the Cox model showed that the risk of CKD among women with PCOS and healthy women is comparable and women with PCOS did not have a higher risk of developing CKD compared to healthy women (unadjusted HR: 0.883; 95% CI: 0.587‐1.328; P  = .551). The results remained unchanged after adjustment for potential confounders of smoking status, BMI, hypertension and diabetes at baseline and follow‐up of study (multiple adjusted HR: 0.911; 95% CI: 0.600‐1.383; P  = .661). Conclusion Our population‐based study with a long‐term follow‐up period showed that the risk of CKD in PCOS patients was similar to the general female population. Large studies, with long‐term follow‐up and more diverse phenotypes, are needed to confirm the findings.
    Type of Medium: Online Resource
    ISSN: 0300-0664 , 1365-2265
    URL: Issue
    URL: Article
    DOI: 10.1111/cen.v93.5
    DOI: 10.1111/cen.14284
    RVK:
    XA 10000
    Language: English
    Publisher: Wiley
    Publication Date: 2020
    detail.hit.zdb_id: 121745-8
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  • 2
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    Increased Remission Rates After Long-Term Methimazole Therapy in Patients with Graves' Disease: Results of a Randomized Clinical Trial
    Mary Ann Liebert Inc ; 2019
    In:  Thyroid Vol. 29, No. 9 ( 2019-09-01), p. 1192-1200
    Details
    In: Thyroid, Mary Ann Liebert Inc, Vol. 29, No. 9 ( 2019-09-01), p. 1192-1200
    Type of Medium: Online Resource
    ISSN: 1050-7256 , 1557-9077
    URL: Article
    DOI: 10.1089/thy.2019.0180
    Language: English
    Publisher: Mary Ann Liebert Inc
    Publication Date: 2019
    detail.hit.zdb_id: 1086044-7
    detail.hit.zdb_id: 2030622-2
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  • 3
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    Prognostic value of different maternal obesity phenotypes in predicting offspring obesity in a family-based cohort study
    Springer Science and Business Media LLC ; 2021
    In:  BMC Public Health Vol. 21, No. 1 ( 2021-12)
    Details
    In: BMC Public Health, Springer Science and Business Media LLC, Vol. 21, No. 1 ( 2021-12)
    Abstract: Parental weight is studied as an important determinant of childhood obesity; however, obesity-related metabolic abnormalities have been less considered as determinants of childhood obesity. This study aimed to investigate the association between maternal obesity phenotypes and incidence of obesity in their offspring. Methods This longitudinal study was conducted within the framework of the Tehran Lipid and Glucose Study. A total of 2151 non-obese children who had complete parental information were followed for incidence of obesity over a mean of 148.7 ± 34.7 months. Obesity in children was defined using the World Health Organization criteria. Maternal body mass index (BMI) was classified into three categories: normal weight, overweight and obese. Dysmetabolic status was considered as having metabolic syndrome or diabetes. Metabolic syndrome and diabetes were defined according to the Joint Interim Statement and American diabetes association criteria, respectively. Considering maternal BMI categories and metabolic status, six obesity phenotypes were defined as followed: 1) normal weight and normal metabolic status, 2) overweight and normal metabolic status, 3) obese and normal metabolic status, 4) normal weight and dysmetabolic status, 5) overweight and dysmetabolic status, and 6) obese and dysmetabolic status. The association between maternal obesity phenotypes and incidence of obesity in children was studied using Cox proportional regression hazard model. Results In male offspring, the risk of incidence of obesity significantly increased in those with maternal obesity phenotypes including overweight/normal metabolic: 1.75(95% CI: 1.10–2.79), obese/normal metabolic: 2.60(95%CI: 1.51–4.48), overweight/dysmetabolic: 2.34(95%CI: 1.35–4.03) and obese/dysmetabolic: 3.21(95%CI: 1.94–5.03) compared to the normal weight/normal metabolic phenotype. Similarly, in girls, the risk of incidence of obesity significantly increased in offspring with maternal obesity phenotypes including overweight/normal metabolic: 2.39(95%CI: 1.46–3.90), obese/normal metabolic: 3.55(95%CI: 1.94–6.46), overweight/dysmetabolic: 1.92(95%CI: 1.04–3.52) and obese/dysmetabolic: 3.89(95%CI: 2.28–6.64) compared to normal weight/normal metabolic phenotype. However, maternal normal weight/dysmetabolic phenotype did not significantly change the risk of obesity in both male and female offspring. Conclusion Except for normal weight/dysmetabolic phenotype, all maternal obesity phenotypes had significant prognostic values for incidence of offspring obesity with the highest risk for obese/dysmetabolic phenotype. This study provides valuable findings for identifying the first line target groups for planning interventions to prevent childhood obesity.
    Type of Medium: Online Resource
    ISSN: 1471-2458
    URL: Article
    DOI: 10.1186/s12889-021-10932-4
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2041338-5
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  • 4
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    Effectiveness of a practical multi-setting lifestyle intervention on the main BMI trajectories from childhood to young adulthood: A community-based trial
    Springer Science and Business Media LLC ; 2022
    In:  BMC Public Health Vol. 22, No. 1 ( 2022-10-31)
    Details
    In: BMC Public Health, Springer Science and Business Media LLC, Vol. 22, No. 1 ( 2022-10-31)
    Abstract: Preventing overweight in childhood and subsequent stages of life is still a global challenge. Despite numerous relevant lifestyle interventions, data on their impact on different BMI change pathways over time is rare. The present study aimed to investigate the effect of a multi-setting lifestyle intervention on BMI trajectories from childhood to young adulthood. Methods A multi-setting lifestyle intervention at the school, family, and community levels have been conducted in the Tehran Lipid and Glucose Study framework. A total of 2145 children (4–18 years, 49% boys, and 18% intervention) were recruited for the baseline assessment and were followed through five follow-up examinations during a median of 16.1 years. Using a group-based trajectory model, BMI trajectories from childhood to young adulthood were identified, and their association with the implemented intervention was assessed. Results Four trajectory groups of BMI from childhood to young adulthood were identified, including Normal weight (41%), Young adulthood overweight (36%), Early childhood increasing overweight and adulthood obesity (19%), and Early childhood increasing obesity (4%). Only Young adulthood overweight and Early childhood increasing obesity were affected by the intervention and were concomitant with lower BMI levels than the control group, with the highest estimated effect in the latter (β=-0.52 and p = 0.018; β=-1.48 and p  〈  0.001, respectively). Conclusion The current findings indicate the highest effectiveness of a practical, healthy lifestyle intervention on those whose obesity started in the early years of life or youth. Our results could help policymakers and planners design more targeted lifestyle modification and weight control interventions. Trial registration This study is registered at Iran Registry for Clinical Trials, a WHO primary registry ( http://irct.ir ). The Iran Registry for Clinical Trials ID and date are IRCTID:IRCT138705301058N1, 29/10/2008.
    Type of Medium: Online Resource
    ISSN: 1471-2458
    URL: Article
    DOI: 10.1186/s12889-022-14306-2
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2022
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  • 5
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    Predisposing factors of long-term responsiveness in a cardio-metabolic cohort: Tehran Lipid and Glucose Study
    Springer Science and Business Media LLC ; 2021
    In:  BMC Medical Research Methodology Vol. 21, No. 1 ( 2021-12)
    Details
    In: BMC Medical Research Methodology, Springer Science and Business Media LLC, Vol. 21, No. 1 ( 2021-12)
    Abstract: Non-participation in cohort studies, if associated with both the exposure and occurrence of the event, can introduce bias in the estimates of interest. This study aims to identify factors associated with follow-up participation in Tehran Lipid and Glucose Study, a large-scale community-based prospective study in West Asia. Methods A sample of 10,368 adults from TLGS was included in the analysis. All analyses were split according to sex and age groups (20–39, 40–59, and 60 years). The associations between socio-demographic, health, and lifestyle factors with response rate were identified using the Generalized Estimating Equations model. Results Over the median of 15.7 years of follow up the response rate was 64.5%. The highest response rate was observed in those aged 40–59 years for both sexes. Current smokers had lower odds of response in both sexes for all age groups, ranging from 0.51 to 0.74, p   〈  0.01. In young adults, being single (OR = 0.79, OR = 0.57, p  ≤ 0.01, respectively for men and women) and unemployed (OR = 0.73, OR = 0.76, p  ≤ 0.01, respectively for men and women) in both sexes, high physical activity in men (OR = 0.77, p   〈  0.01), high education (OR = 0.75, p  = 0.02) and obesity (OR = 0.85, p  = 0.05) in women were associated with lower response rate. For the middle-aged group, diabetes in men (OR = 0.77, p  = 0.05) and hypertension (OR = 0.84, p  = 0.05), and having a history of cancer (OR = 0.43, p  = 0.03) in women were factors associated with lower response rates. Finally, interventions for both sexes (OR = 0.75, OR = 0.77, p  ≤ 0.05, respectively for men and women) and being divorced/widow in women (OR = 0.77, p  = 0.05) were the factors associated with the lower response rate in the elderly. Conclusions Long-term participation was influenced by socio-demographic, health, and lifestyle factors in different sex- and age-specific patterns in TLGS. Recruitment strategies targeting these factors may improve participant follow-up in longitudinal studies.
    Type of Medium: Online Resource
    ISSN: 1471-2288
    URL: Article
    DOI: 10.1186/s12874-021-01351-5
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2041362-2
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  • 6
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    Clarification of ethical principle of the beneficence in nursing care: an integrative review
    Springer Science and Business Media LLC ; 2023
    In:  BMC Nursing Vol. 22, No. 1 ( 2023-03-30)
    Details
    In: BMC Nursing, Springer Science and Business Media LLC, Vol. 22, No. 1 ( 2023-03-30)
    Abstract: Ethics-based nursing practice can transform health care practices. As the biggest human capital in the health care system, nurses are obliged to follow ethical principles in this field. One of these ethical principles; is beneficence, which is considered the core of nursing care. This study aimed to investigate clarification of the principle of beneficence in nursing care and its related challenges. Methods This integrative review was conducted using the Whittemore & Knafl method in 5 stages, including problem identification, searching the literature, evaluating primary sources, analyzing data, and presenting the results. Databases like SID, Irandoc, Magiran, Google Scholar, Web of Science, PubMed, and Scopus were searched using the keywords; “beneficence”, “ethic”, “nursing” and “care” in English and Persian in the time range of 2010 to 10 February, 2023. After applying inclusion criteria and assessing the articles using Bowling’s Quality Assessment Tool, finally, 16 papers were included from 984. Results After reviewing and evaluating the qualified articles, the findings were classified into four main categories: (1) nature, (2) applicability, (3) Relevant and influential factors, and (4) challenges related to the ethical principle of beneficence in nursing care. Conclusion Based on the results of this review it seems that paying attention to clarification the principle of beneficence in nursing care can provide positive outcomes for patients to benefit from this principle and finally, it leads to increasing the well-being and health of patients, reducing their mortality rate, increasing satisfaction and maintaining the respect and human dignity of patients.
    Type of Medium: Online Resource
    ISSN: 1472-6955
    URL: Article
    DOI: 10.1186/s12912-023-01246-4
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
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  • 7
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    The Kalirin Gene rs9289231 Polymorphism as a Novel Predisposing Marker for Coronary Artery Disease
    Oxford University Press (OUP) ; 2014
    In:  Laboratory Medicine Vol. 45, No. 4 ( 2014-11), p. 302-308
    Details
    In: Laboratory Medicine, Oxford University Press (OUP), Vol. 45, No. 4 ( 2014-11), p. 302-308
    Type of Medium: Online Resource
    ISSN: 0007-5027 , 1943-7730
    URL: Article
    DOI: 10.1309/LMLS813ZDPHRFLUU
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2014
    detail.hit.zdb_id: 2166586-2
    detail.hit.zdb_id: 2100869-3
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  • 8
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    Risk of recurrence at the time of withdrawal of short- or long-term methimazole therapy in patients with Graves’ hyperthyroidism: a randomized trial and a risk-scoring model
    Springer Science and Business Media LLC ; 2024
    In:  Endocrine Vol. 84, No. 2 ( 2024-01-02), p. 577-588
    Details
    In: Endocrine, Springer Science and Business Media LLC, Vol. 84, No. 2 ( 2024-01-02), p. 577-588
    Type of Medium: Online Resource
    ISSN: 1559-0100
    URL: Article
    DOI: 10.1007/s12020-023-03656-5
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2024
    detail.hit.zdb_id: 2074043-8
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  • 9
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    The Long‐Term Effectiveness of a Multisetting Lifestyle Intervention on Tobacco‐Related Habits in Adolescent Boys and Girls: Tehran Lipid and Glucose Study
    Wiley ; 2022
    In:  Journal of School Health Vol. 92, No. 9 ( 2022-09), p. 888-897
    Details
    In: Journal of School Health, Wiley, Vol. 92, No. 9 ( 2022-09), p. 888-897
    Abstract: This study assesses the long‐term effectiveness of a lifestyle intervention on cigarette, passive, and hookah smoking in adolescent boys and girls. METHODS One thousand one hundred and fifty‐nine adolescent participants of Tehran Lipid and Glucose Study (TLGS) (2001‐2004) were followed for 12 years. Participants in the intervention area received lifestyle interventions in family, schools, and community settings, with the largest part implemented in schools. After excluding those with missing baseline parental data (n = 66), complete parental data of 1093 adolescents was used for cluster analysis. Families were classified as low‐ and high‐risk. Two hundred and ninety‐six individuals who did not complete intervention/follow‐ups were excluded, GEE was performed on 797 adolescents (369 boys, 192 intervention) to assess the intervention effect on tobacco‐related habits. RESULTS Adolescents' mean baseline age was 15.21 ± 1.95. Those living in high‐risk families were more at risk of cigarette, passive, and hookah smoking. Intervention decreased odds of cigarette and passive smoking by 38% and 57%, respectively. Intervention did not reduce hookah smoking in adolescents. After sex‐specific analysis, the intervention reduced current cigarette smoking by 40% only in boys and passive smoking in both sexes. CONCLUSIONS Targeting lifestyle behaviors in school‐aged adolescents and their families reduces cigarette smoking in boys and protects both sexes from secondhand smoke.
    Type of Medium: Online Resource
    ISSN: 0022-4391 , 1746-1561
    URL: Issue
    URL: Article
    DOI: 10.1111/josh.v92.9
    DOI: 10.1111/josh.13193
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2066647-0
    detail.hit.zdb_id: 952835-0
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  • 10
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    The association between leisure-time physical activity and blood pressure changes from adolescence to young adulthood: Tehran Lipid and Glucose Study
    Springer Science and Business Media LLC ; 2023
    In:  Scientific Reports Vol. 13, No. 1 ( 2023-11-28)
    Details
    In: Scientific Reports, Springer Science and Business Media LLC, Vol. 13, No. 1 ( 2023-11-28)
    Abstract: The effectiveness of long-term leisure time physical activity (LTPA) on blood pressure (BP) changes is still under debate. Since adolescence lifestyle behaviors shape the adulthood health profile, this study aimed to investigate the sex-specific impact of LTPA on BP changes from adolescence to young adulthood. This longitudinal study uses the data of 1412 adolescents (52% females) aged 12–18 years through a median follow-up of 12.2 years in the Tehran Lipid and Glucose Study (TLGS) framework. LTPA was calculated using the reliable and valid Iranian version of the modified activity scale (MAQ), and BP was measured at least twice by trained physicians. The linear mixed model was used to examine the study variables, considering individual and intrapersonal differences during the study. The majority of participants consistently demonstrated insufficient LTPA throughout the follow-up assessments, ranging from 54.7 to 67.1% for males and 77.7–83.4% for females. Despite a declining trend in LTPA (β = − 2.77 for males and β = − 1.43 for females), an increasing trend was noticeable in SBP, DBP, and BMI (β = 1.38, β = 1.81, β = 0.97 for males, and β = 0.10, β = 0.20, β = 0.97 for females, respectively). The unadjusted model revealed a significant trend in all variables for both sexes, except for female BP (P = 0.45 for SBP and P = 0.83 for DBP). Using the adjusted model, no significant association was observed between LTPA and changes in BP over time in both sexes. Our study indicates no association between LTPA and BP changes from adolescence to young adulthood. Insufficient LTPA levels, particularly among Iranian females, are likely the primary factor. Further research is crucial to identify appropriate LTPA levels to promote cardiovascular health and implement targeted interventions to achieve optimal LTPA levels in the Iranian population.
    Type of Medium: Online Resource
    ISSN: 2045-2322
    URL: Article
    DOI: 10.1038/s41598-023-48253-8
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2023
    detail.hit.zdb_id: 2615211-3
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