In:
Advanced Synthesis & Catalysis, Wiley, Vol. 361, No. 2 ( 2019-01-22), p. 297-306
Abstract:
Carboxylation reactions of diamines were found to proceed rapidly and non‐catalytically, producing corresponding cyclic ureas in excellent yields and selectivities when 2‐pyrrolidone (2‐PY) was used as a solvent. A similar promoting effect with 2‐PY was also observed for the carboxylation of monoamines by carbon dioxide (CO 2 ). Most notably, the carboxylation reactions of mono‐ and diamines conducted in 2‐PY afforded 2–4 times higher yields of corresponding dialkyl ureas and cyclic ureas compared with those in N ‐methyl‐2‐pyrrolidone (NMP). Such a dramatic promoting effect using 2‐PY is believed to be associated with the multiple hydrogen bonding interactions between 2‐PY and the CO 2 ‐containing species of amines. Due to such favorable interactions, carboxylation reactions seem to be more facilitated in 2‐PY than in NMP. magnified image
Type of Medium:
Online Resource
ISSN:
1615-4150
,
1615-4169
DOI:
10.1002/adsc.201800945
Language:
English
Publisher:
Wiley
Publication Date:
2019
detail.hit.zdb_id:
2041384-1
detail.hit.zdb_id:
2033084-4
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