In:
Frontiers in Veterinary Science, Frontiers Media SA, Vol. 9 ( 2022-1-31)
Abstract:
This study was conducted to investigate the effects of zinc methionine (Zn-Met) on the growth performance, antioxidant capacity and intestinal barrier function of meat ducks. Three hundred and sixty 1-day-old male Cherry Valley ducks were randomly divided into 6 groups with 6 replicates (10 birds each), and fed diets with 0, 30, 60, 90, 120 or 150 mg/kg Zn for 35 d. The results indicated that dietary supplementation with Zn-Met substantially increased the average daily gain (ADG), and reduced the feed to gain ratio (F/G) during 1–35 d ( P & lt; 0.05). Dietary Zn-Met markedly increased the activity of superoxide dismutase (SOD), catalase (CAT) and glutathione (GSH), and reduced the malondialdehyde (MDA) content in the jejunum ( P & lt; 0.05). The mRNA expression levels of critical antioxidant enzymes such as SOD, CAT , and nuclear factor erythroid 2-related factor 2 ( Nrf2 ) were increased by Zn in the jejunum ( P & lt; 0.05). Supplementation with 60, 90, 120, and 150 mg/kg of Zn significantly reduced the diamine oxidase (DAO) activity in the serum ( P & lt; 0.05). Different levels of Zn can increase the mRNA expression of occluding ( OCLN) and zonula occludens-1 ( ZO-1) in the jejunum ( P & lt; 0.05). Diets supplemented with zinc significantly increased the content of mucin2 (MUC2), secretory immunoglobulin A (sIgA), immunoglobulin A (IgA) and immunoglobulin G (IgG) in the jejunum of meat ducks ( P & lt; 0.05). The 16S rRNA sequence analysis indicated that 150 mg/kg of Zn had a higher relative abundance of Verrucomicrobia and Akkermansia in cecal digesta ( P & lt; 0.05). In conclusion, Zn-Met improved the growth performance of meat ducks by enhancing intestinal antioxidant capacity and intestinal barrier function. This study provides data support for the application of Zn-Met in meat duck breeding.
Type of Medium:
Online Resource
ISSN:
2297-1769
DOI:
10.3389/fvets.2022.774160
Language:
Unknown
Publisher:
Frontiers Media SA
Publication Date:
2022
detail.hit.zdb_id:
2834243-4
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