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  • 1
    Online Resource
    Online Resource
    Simultaneous enhancements on emissions from quantum dot and quantum well by Ag nanoparticles for color conversion
    IOP Publishing ; 2024
    In:  Semiconductor Science and Technology
    Details
    In: Semiconductor Science and Technology, IOP Publishing
    Abstract: Quantum dots (QDs) have been paid much attention on the color conversion for light-emitting diode (LED) in micro-display recently. However, it is hard to achieve high color conversion efficiency in a thin QD layer. In this paper, we fabricated silver nanoparticles (Ag NPs) with radii ranging mostly from 25 to 35 nm on a blue LED with a peak wavelength of 450 nm, then spin-coated QDs with a peak wavelength of 565 nm. Scanning electron microscopy (SEM), cathodoluminescence (CL), photoluminescence (PL), and time-resolved PL (TRPL) measurements were performed. The PL emissions from quantum wells (QWs) of blue LED and QDs were enhanced by 10% and 32%, respectively, when the Ag NPs were included. The PL lifetimes of QWs and QDs were reduced by 10 and 6 times, respectively, compared to their initial states. Finite Difference Time Domain (FDTD) software and the perturbation method were used to simulate the PL measurements and variable separation. It was concluded that the coupling of QDs and QWs with localized surface plasmon (LSP) improves the external quantum efficiency (EQE) and enhances the spontaneous emission rate in both QWs and QDs. This paper provides a new idea for designing high-efficiency color conversion micro-LED.
    Type of Medium: Online Resource
    ISSN: 0268-1242 , 1361-6641
    URL: Article
    DOI: 10.1088/1361-6641/ad3275
    RVK:
    UA 7761
    Language: Unknown
    Publisher: IOP Publishing
    Publication Date: 2024
    detail.hit.zdb_id: 54647-1
    detail.hit.zdb_id: 1361285-2
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  • 2
    Online Resource
    Online Resource
    Knowledge, Perceived Beliefs, and Preventive Behaviors Related to COVID-19 Among Chinese Older Adults: Cross-Sectional Web-Based Survey
    JMIR Publications Inc. ; 2020
    In:  Journal of Medical Internet Research Vol. 22, No. 12 ( 2020-12-31), p. e23729-
    Details
    In: Journal of Medical Internet Research, JMIR Publications Inc., Vol. 22, No. 12 ( 2020-12-31), p. e23729-
    Abstract: The COVID-19 pandemic continues to pose an international public health threat. Prevention is of paramount importance to protect the high-risk group of older adults until specific treatments for COVID-19 become available; however, little work has been done to explore factors that promote preventive behaviors among this population. Objective This study aims to investigate the knowledge, perceived beliefs, and preventive behaviors towards COVID-19 of older adults in China and determine the factors that influence their practice of preventive behaviors. Methods From February 19 to March 19, 2020, a cross-sectional, web-based survey was administered to Chinese older adults in all 31 provinces of mainland China using a convenience sampling method to assess the respondents’ knowledge, perceived beliefs, and preventive behaviors towards COVID-19. Standard descriptive statistics and hierarchical linear regression analyses were conducted to analyze the data. Results A total of 1501 participants responded to the survey, and 1263 valid responses (84.1%) were obtained for further analysis. The overall correct rate on the knowledge questionnaire was 87%, overall positive beliefs regarding COVID-19 were found, and the mean behavior score was 13.73/15 (SD 1.62, range 5-15). The hierarchical linear regression showed that respondents who were married or cohabitating and who lived in areas with community-level control measures were more likely to practice preventive behaviors (P 〈 .01). Knowledge (β=0.198, P 〈 .001), perceived susceptibility (β=0.263, P=.03), perceived benefits (β=0.643, P 〈 .001), and self-efficacy in preventing COVID-19 (β=0.468, P 〈 .001) were also found to be significantly associated with preventive behaviors. Conclusions Most older residents had adequate knowledge and positive beliefs regarding COVID-19 and engaged in proactive behaviors to prevent the disease. Knowledge and beliefs were confirmed to be significantly associated with behavior responses. Our findings have significant implications in enhancing the effectiveness of COVID-19 prevention programs targeting the older population; these programs must be continued and strengthened as the epidemic continues.
    Type of Medium: Online Resource
    ISSN: 1438-8871
    URL: Article
    DOI: 10.2196/23729
    Language: English
    Publisher: JMIR Publications Inc.
    Publication Date: 2020
    detail.hit.zdb_id: 2028830-X
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  • 3
    Online Resource
    Online Resource
    Life in a New Normal with a Self-Care Routine: A Cross-Sectional Study of Older Adults’ Daily Health Behaviors (DHB) Performance during the Initial Outbreak of COVID-19 in China
    MDPI AG ; 2022
    In:  Nutrients Vol. 14, No. 8 ( 2022-04-18), p. 1678-
    Details
    In: Nutrients, MDPI AG, Vol. 14, No. 8 ( 2022-04-18), p. 1678-
    Abstract: For older adults, self-care begins with daily health behaviors (DHB), which refers to a series of basic behaviors beneficial to health in daily life; it is the foundation for promoting health, preventing disease, and maintaining health with or without the support of a healthcare provider. Thus, this study aimed to observe the changes in DHB among older adults when the COVID-19 pan-demic first erupted in China (at the beginning of 2020) and explore the impact factors on self-care routines in daily life. We applied a cross-sectional study among 1256 (83.7%) valid older Chinese from 19 February 2020 to 19 March 2020, the score of DHB changes (mean ± SD, 14.70 ± 2.140; range, 8–18) presented a significant growth (t1256 = 44.636, p 〈 0.001) during COVID-19. From 3 hierarchical linear regression models, the older Chinese who received a higher education include high school (β = 0.403, 95% CI [0.009, 0.797], p = 0.045) and college degree and above (β = 0.488, 95% CI [0.034, 0.943] , p = 0.035), and lived in the eastern China (β = 0.771, 95% CI [0.392, 1.151], p 〈 0.001) took DHB more frequently. However, the high-risk infection (β = −0.740, 95% CI [−1.248, −0.231], p = 0.004), overweight/obese character (β = −0.265, 95% CI [−0.526, −0.004] , p = 0.047), and alcohol consumption (β = −0.350, 95% CI [−0.634, −0.065], p = 0.016) are significant factors in decreasing a senior’s DHB performance. For China, self-care offers a straightforward strategy among the range of measures required to combat COVID-19 and future health threats. In summary, findings in this study can build a foundation for developing healthcare policy and services for the relevant government and departments on prompting DHB and the importance of self-care among the older population.
    Type of Medium: Online Resource
    ISSN: 2072-6643
    URL: Article
    DOI: 10.3390/nu14081678
    Language: English
    Publisher: MDPI AG
    Publication Date: 2022
    detail.hit.zdb_id: 2518386-2
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  • 4
    Online Resource
    Online Resource
    Table_2.docx
    Frontiers Media SA ; 2021
    In:  Frontiers in Psychiatry Vol. 12 ( 2021-5-12)
    Details
    In: Frontiers in Psychiatry, Frontiers Media SA, Vol. 12 ( 2021-5-12)
    Abstract: Background: COVID-19 not only threatened the public's physical health but also brought unbearable psychological pressure, especially for those vulnerable groups like the elderly. However, studies on the psychological status of older adults during this public health emergency remained scant. This study aims to investigate the mental health status among the elderly Chinese population during COVID-19 pandemic and determine the influencing factors of psychological symptoms. Methods: From February 19 to March 19, 2020, an online survey was administered to Chinese older adults using a convenience sampling method. Information on demographic data, health status and other epidemic related factors were collected. Specifically, the study defined the psychological status as five primary disorder–depression, neurasthenia, fear, anxiety, and hypochondria–which were assessed by the Psychological Questionnaire for Emergent Event of Public Health (PQEEPH). Standard descriptive statistics and multiple logistic regression analyses were conducted to analyze the data. Results: Of 1,501 participants recruited from 31 provinces in China, 1,278 were valid for further analysis. Participants' scores on each sub-scale were described in median and interquartile [M(Q)]: depression [0.00 (0.33)] , neurasthenia [0.00 (0.40)], fear [1.00 (0.83)] , anxiety [0.00 (0.17)], hypochondria [0.00 (0.50)] . Chronic diseases (depression p = 0.001; neurasthenia p & lt; 0.001; fear p = 0.023; anxiety p & lt; 0.001; hypochondria p = 0.001) and the BMI index (depression p = 0.015; neurasthenia p = 0.046; fear p = 0.016; anxiety p = 0.015; hypochondria p = 0.013) had significant impacts on all of the five sub-scales. Specifically, the rural dwellers had a higher level of neurasthenia, fear, and hypochondria. Besides, education level ( p = 0.035) and outbreak risk level ( p = 0.004) had significant impacts on the depression. Higher household monthly income per capita ( p = 0.031), and the community-level entry/exit control ( p = 0.011) are factors against anxiety. Conclusions: Most elderly residents reported mild negative emotions during COVID-19 and more attention should be paid to the recognition and alleviation of fear. Our findings also identified factors associated with the mental health status of the elderly, which is of practical significance in the design and implementation of psychological interventions for this vulnerable population during COVID-19 and future emerging diseases.
    Type of Medium: Online Resource
    ISSN: 1664-0640
    URL: Article
    URL: Article
    URL: Article
    DOI: 10.3389/fpsyt.2021.645938
    DOI: 10.3389/fpsyt.2021.645938.s001
    DOI: 10.3389/fpsyt.2021.645938.s002
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2021
    detail.hit.zdb_id: 2564218-2
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  • 5
    Online Resource
    Online Resource
    The lower correlated color temperature with higher illuminance nocturnal light environment improves cognitive performance and sleep quality
    Elsevier BV ; 2024
    In:  Building and Environment Vol. 251 ( 2024-03), p. 111221-
    Details
    In: Building and Environment, Elsevier BV, Vol. 251 ( 2024-03), p. 111221-
    Type of Medium: Online Resource
    ISSN: 0360-1323
    URL: Article
    DOI: 10.1016/j.buildenv.2024.111221
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2024
    detail.hit.zdb_id: 1481962-4
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  • 6
    Online Resource
    Online Resource
    Knockout of SlALKBH2 weakens the DNA damage repair ability of tomato
    Elsevier BV ; 2022
    In:  Plant Science Vol. 319 ( 2022-06), p. 111266-
    Details
    In: Plant Science, Elsevier BV, Vol. 319 ( 2022-06), p. 111266-
    Type of Medium: Online Resource
    ISSN: 0168-9452
    URL: Article
    DOI: 10.1016/j.plantsci.2022.111266
    RVK:
    WA 15000
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2022
    detail.hit.zdb_id: 1498605-X
    SSG: 12
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  • 7
    Online Resource
    Online Resource
    SlERF.J2 reduces chlorophyll accumulation and inhibits chloroplast biogenesis and development in tomato leaves
    Elsevier BV ; 2023
    In:  Plant Science Vol. 328 ( 2023-03), p. 111578-
    Details
    In: Plant Science, Elsevier BV, Vol. 328 ( 2023-03), p. 111578-
    Type of Medium: Online Resource
    ISSN: 0168-9452
    URL: Article
    DOI: 10.1016/j.plantsci.2022.111578
    RVK:
    WA 15000
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 1498605-X
    SSG: 12
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  • 8
    Online Resource
    Online Resource
    The effects of DL‐3‐n‐butylphthalide in patients with vascular cognitive impairment without dementia caused by subcortical ischemic small vessel disease: A multicentre, randomized, double‐blind, placebo‐controlled trial
    Wiley ; 2016
    In:  Alzheimer's & Dementia Vol. 12, No. 2 ( 2016-02), p. 89-99
    Details
    In: Alzheimer's & Dementia, Wiley, Vol. 12, No. 2 ( 2016-02), p. 89-99
    Abstract: Vascular cognitive impairment without dementia is very common among the aged and tends to progress to dementia, but there have been no proper large‐scale intervention trials dedicated to it. Vascular cognitive impairment without dementia caused by subcortical ischemic small vessel disease (hereinafter, subcortical Vascular cognitive impairment without dementia) represents a relatively homogeneous disease process and is a suitable target for therapeutic trials investigating Vascular cognitive impairment without dementia. Preclinical trials showed that dl‐3‐n‐butylphthalide (NBP) is effective for cognitive impairment of vascular origin. Methods In this randomized, double‐blind, placebo‐controlled trial, we enrolled patients aged 50–70 years who had a diagnosis of subcortical Vascular cognitive impairment without dementia at 15 academic medical centers in China. Inclusion criteria included a clinical dementia rating ≥0.5 on at least one domain and global score ≤0.5; a mini‐mental state examination score ≥20 (primary school) or ≥24 (junior school or above); and brain magnetic resonance imaging consistent with subcortical ischemic small vessel disease. Patients were randomly assigned to NBP 200 mg three times daily or matched placebo (1:1) for 24 weeks according to a computer‐generated randomization protocol. All patients and study personnel were masked to treatment assignment. Primary outcome measures were the changes in Alzheimer's disease assessment scale‐cognitive subscale (ADAS‐cog) and clinician's interview‐based impression of change plus caregiver input (CIBIC‐plus) after 24 weeks. All patients were monitored for adverse events (AEs). Outcome measures were analyzed for both the intention‐to‐treat (ITT) population and the per protocol population. Results This study enrolled 281 patients. NBP showed greater effects than placebo on ADAS‐cog (NBP change −2.46 vs. placebo −1.39; P  = .03; ITT) and CIBIC‐plus (80 [57.1%] vs. 59 [42.1%] patients improved; P  = .01; ITT). NBP‐related AE were uncommon and primarily consisted of mild gastrointestinal symptoms. Discussion Over the 6‐month treatment period, NBP was effective for improving cognitive and global functioning in patients with subcortical vascular cognitive impairment without dementia and exhibited good safety.
    Type of Medium: Online Resource
    ISSN: 1552-5260 , 1552-5279
    URL: Article
    DOI: 10.1016/j.jalz.2015.04.010
    Language: English
    Publisher: Wiley
    Publication Date: 2016
    detail.hit.zdb_id: 2201940-6
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  • 9
    Online Resource
    Online Resource
    Finerenone in Patients With Chronic Kidney Disease and Type 2 Diabetes According to Baseline HbA1c and Insulin Use: An Analysis From the FIDELIO-DKD Study
    American Diabetes Association ; 2022
    In:  Diabetes Care Vol. 45, No. 4 ( 2022-04-01), p. e888-e897
    Details
    In: Diabetes Care, American Diabetes Association, Vol. 45, No. 4 ( 2022-04-01), p. e888-e897
    Abstract: Finerenone significantly improved cardiorenal outcomes in patients with chronic kidney disease (CKD) and type 2 diabetes (T2D) in the Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease trial. We explored whether baseline HbA1c level and insulin treatment influenced outcomes. RESEARCH DESIGN AND METHODS Patients with T2D, urine albumin-to-creatinine ratio (UACR) of 30–5,000 mg/g, estimated glomerular filtration rate (eGFR) of 25 to & lt;75 mL/min/1.73 m2, and treated with optimized renin–angiotensin system blockade were randomly assigned to receive finerenone or placebo. Efficacy outcomes included kidney (kidney failure, sustained decrease ≥40% in eGFR from baseline, or renal death) and cardiovascular (cardiovascular death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure) composite endpoints. Patients were analyzed by baseline insulin use and by baseline HbA1c & lt;7.5% (58 mmol/mol) or ≥7.5%. RESULTS Of 5,674 patients, 3,637 (64.1%) received insulin at baseline. Overall, 5,663 patients were included in the analysis for HbA1c; 2,794 (49.3%) had baseline HbA1c & lt;7.5% (58 mmol/mol). Finerenone significantly reduced risk of the kidney composite outcome independent of baseline HbA1c level and insulin use (Pinteraction = 0.41 and 0.56, respectively). Cardiovascular composite outcome incidence was reduced with finerenone irrespective of baseline HbA1c level and insulin use (Pinteraction = 0.70 and 0.33, respectively). Although baseline HbA1c level did not affect kidney event risk, cardiovascular risk increased with higher HbA1c level. UACR reduction was consistent across subgroups. Adverse events were similar between groups regardless of baseline HbA1c level and insulin use; few finerenone-treated patients discontinued treatment because of hyperkalemia. CONCLUSIONS Finerenone reduces kidney and cardiovascular outcome risk in patients with CKD and T2D, and risks appear consistent irrespective of HbA1c levels or insulin use.
    Type of Medium: Online Resource
    ISSN: 0149-5992
    URL: Article
    DOI: 10.2337/dc21-1944
    Language: English
    Publisher: American Diabetes Association
    Publication Date: 2022
    detail.hit.zdb_id: 1490520-6
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  • 10
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    Online Resource
    Finerenone in Patients With Chronic Kidney Disease and Type 2 Diabetes by Sodium–Glucose Cotransporter 2 Inhibitor Treatment: The FIDELITY Analysis
    American Diabetes Association ; 2022
    In:  Diabetes Care Vol. 45, No. 12 ( 2022-12-01), p. 2991-2998
    Details
    In: Diabetes Care, American Diabetes Association, Vol. 45, No. 12 ( 2022-12-01), p. 2991-2998
    Abstract: Finerenone reduced the risk of kidney and cardiovascular events in people with chronic kidney disease (CKD) and type 2 diabetes in the FIDELIO-DKD and FIGARO-DKD phase 3 studies. Effects of finerenone on outcomes in patients taking sodium–glucose cotransporter 2 inhibitors (SGLT2is) were evaluated in a prespecified pooled analysis of these studies. RESEARCH DESIGN AND METHODS Patients with type 2 diabetes and urine albumin-to-creatinine ratio (UACR) ≥30 to ≤5,000 mg/g and estimated glomerular filtration rate (eGFR) ≥25 mL/min/1.73 m2 were randomly assigned to finerenone or placebo; SGLT2is were permitted at any time. Outcomes included cardiovascular composite (cardiovascular death, nonfatal myocardial infarction, nonfatal stroke, or hospitalization for heart failure) and kidney composite (kidney failure, sustained ≥57% eGFR decline, or renal death) end points, changes in UACR and eGFR, and safety outcomes. RESULTS Among 13,026 patients, 877 (6.7%) received an SGLT2i at baseline and 1,113 (8.5%) initiated one during the trial. For the cardiovascular composite, the hazard ratios (HRs) were 0.87 (95% CI 0.79–0.96) without SGLT2i and 0.67 (95% CI 0.42–1.07) with SGLT2i. For the kidney composite, the HRs were 0.80 (95% CI 0.69–0.92) without SGLT2i and 0.42 (95% CI 0.16–1.08) with SGLT2i. Baseline SGLT2i use did not affect risk reduction for the cardiovascular or kidney composites with finerenone (Pinteraction = 0.46 and 0.29, respectively); neither did SGLT2i use concomitant with study treatment. CONCLUSIONS Benefits of finerenone compared with placebo on cardiorenal outcomes in patients with CKD and type 2 diabetes were observed irrespective of SGLT2i use.
    Type of Medium: Online Resource
    ISSN: 0149-5992 , 1935-5548
    URL: Article
    DOI: 10.2337/dc22-0294
    Language: English
    Publisher: American Diabetes Association
    Publication Date: 2022
    detail.hit.zdb_id: 1490520-6
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