In:
FEBS Letters, Wiley, Vol. 184, No. 2 ( 1985-05-20), p. 343-346
Abstract:
Hepatic microsomal lipid peroxidation has been studied in 4 inbred strains of mice: C57BL/6, BALB/c, AKR and DBA/2. The rates of lipid peroxidation stimulated in vitro by carbon tetrachloride, ascorbate‐iron and cumene hydroperoxide were similar in all 4 strains. Lipid peroxidation induced by NADPH/ADP‐iron, however, proceeded at a substantially lower rate in the hepatic microsomes of DBA/2 mice. It is suggested that this low rate of enzymic iron‐induced lipid peroxidation is a factor that may be involved in the resistance of this strain of mice to experimental hepatic porphyria induced by polyhalogenated aromatic hydrocarbons.
Type of Medium:
Online Resource
ISSN:
0014-5793
,
1873-3468
DOI:
10.1016/0014-5793(85)80635-9
Language:
English
Publisher:
Wiley
Publication Date:
1985
detail.hit.zdb_id:
1460391-3
SSG:
12
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