In:
Antimicrobial Agents and Chemotherapy, American Society for Microbiology, Vol. 14, No. 6 ( 1978-12), p. 838-841
Abstract:
Cefamandole, a new cephalosporin antibiotic, has greater activity against common pathogens, including Escherichia coli, Haemophilus influenzae , and Proteus (including indole-positive strains), than available cephalosporin drugs. We have evaluated the safety and pharmacokinetics of this drug in 30 infants and children. Blood levels and urinary excretion of the drug were similar to those previously found in adults. The only side effects were mild and transient elevation of serum glutamic oxalacetic transaminase in 12 patients and of blood urea nitrogen in 1 patient in whom serum creatinine remained normal and unchanged.
Type of Medium:
Online Resource
ISSN:
0066-4804
,
1098-6596
DOI:
10.1128/AAC.14.6.838
Language:
English
Publisher:
American Society for Microbiology
Publication Date:
1978
detail.hit.zdb_id:
1496156-8
SSG:
12
SSG:
15,3
Permalink