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  • 1
    Online Resource
    Online Resource
    The relationship between body mass index and blood pressure: A study among school going children of Rajasthan, India
    Scientific Scholar ; 2021
    In:  Indian Journal of Physiology and Pharmacology Vol. 64 ( 2021-01-12), p. 236-241
    Details
    In: Indian Journal of Physiology and Pharmacology, Scientific Scholar, Vol. 64 ( 2021-01-12), p. 236-241
    Abstract: Hypertension has become common in children and generally remains undiagnosed and untreated. The present study aims to find the prevalence of high blood pressure (BP) and examines the relationship between body mass index (BMI) and BP among school going children. Materials and Methods: A cross-sectional study was conducted among 240 school going children aged between 10 years and 17 years of Udaipur district of Rajasthan. Data were collected using interview schedules and somatometric measurements were taken based on standardized protocols established by the International Society for the Advancement of Kinanthropometry. Data were analyzed using Statistical Package for the Social Sciences software version 20. Hypertension is considered when BP (systolic BP [SBP] and/or diastolic BP [DBP] ) level is ≥95 th percentile for height, age, and sex according to the Fourth Report on the Diagnosis, Evaluation, and Treatment of High BP in Children and Adolescents (2004). Results: It was found that 49% children were underweight, 3% were overweight, and 2% were obese. Hypertension was seen in 39 (16.2%) children (5.4% systolic hypertension, 5.8% diastolic hypertension, and 5% both systolic and diastolic hypertension). Children who were overweight/obese were more likely to have hypertension than those who were normal or underweight. Conclusion: The findings of the present study indicate that BMI is a crucial factor affecting BP levels. Simple measurements of body weight and height to determine BMI as a routine assessment in schools would help in controlling BP levels in children that might cause adulthood morbidity and mortality due to hypertension.
    Type of Medium: Online Resource
    ISSN: 2582-2799 , 0019-5499
    URL: Journal
    URL: Article
    DOI: 10.25259/IJPP
    DOI: 10.25259/IJPP_374_2020
    Language: English
    Publisher: Scientific Scholar
    Publication Date: 2021
    detail.hit.zdb_id: 2562331-X
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  • 2
    Online Resource
    Online Resource
    Epigenetic modification and therapeutic targets of diabetes mellitus
    Portland Press Ltd. ; 2020
    In:  Bioscience Reports Vol. 40, No. 9 ( 2020-09-30)
    Details
    In: Bioscience Reports, Portland Press Ltd., Vol. 40, No. 9 ( 2020-09-30)
    Abstract: The prevalence of diabetes and its related complications are increasing significantly globally. Collected evidence suggested that several genetic and environmental factors contribute to diabetes mellitus. Associated complications such as retinopathy, neuropathy, nephropathy and other cardiovascular complications are a direct result of diabetes. Epigenetic factors include deoxyribonucleic acid (DNA) methylation and histone post-translational modifications. These factors are directly related with pathological factors such as oxidative stress, generation of inflammatory mediators and hyperglycemia. These result in altered gene expression and targets cells in the pathology of diabetes mellitus without specific changes in a DNA sequence. Environmental factors and malnutrition are equally responsible for epigenetic states. Accumulated evidence suggested that environmental stimuli alter the gene expression that result in epigenetic changes in chromatin. Recent studies proposed that epigenetics may include the occurrence of ‘metabolic memory’ found in animal studies. Further study into epigenetic mechanism might give us new vision into the pathogenesis of diabetes mellitus and related complication thus leading to the discovery of new therapeutic targets. In this review, we discuss the possible epigenetic changes and mechanism that happen in diabetes mellitus type 1 and type 2 separately. We highlight the important epigenetic and non-epigenetic therapeutic targets involved in the management of diabetes and associated complications.
    Type of Medium: Online Resource
    ISSN: 0144-8463 , 1573-4935
    URL: Article
    DOI: 10.1042/BSR20202160
    Language: English
    Publisher: Portland Press Ltd.
    Publication Date: 2020
    detail.hit.zdb_id: 2014993-1
    SSG: 12
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  • 3
    Online Resource
    Online Resource
    Disordered eating attitudes and body shape concerns among North Indian Kathak dancers
    Wiley ; 2021
    In:  International Journal of Eating Disorders Vol. 54, No. 2 ( 2021-02), p. 148-154
    Details
    In: International Journal of Eating Disorders, Wiley, Vol. 54, No. 2 ( 2021-02), p. 148-154
    Abstract: To determine the prevalence and association between disordered eating attitudes and body shape concerns in a sample of North Indian Kathak dancers. Method Participants were 206 Kathak female dancers and 235 healthy controls, ages 18–45 years. Participants completed questionnaires assessing demographics, disordered eating attitudes, and body dissatisfaction. Pearson correlations assessed the association between the disordered eating attitudes and body dissatisfaction, and binary logistic regression identified the risk of having a possible eating disorder. Results Kathak dancers reported significantly greater disordered eating attitudes compared to controls (12.1% vs. 5.9%, p = .023). Dancers endorsed greater dieting behaviors ( M = 5.6 vs. 4.5, p = .031), and binge eating episodes ( p   〈  .001) relative to their counterparts. Body dissatisfaction was significantly positively correlated with disordered eating attitudes among the dancers ( p   〈  .001). Dancers with elevated body shape concerns were five times more likely to report disordered eating attitudes, relative to their peers ( p   〈  .001). Discussion Disordered eating attitudes and body shape concerns are prevalent among North Indian Kathak dancers. Future research should aim to develop targeted prevention and intervention programs that focus on reducing these behaviors and promoting a positive body image to mitigate the risk of disordered eating among this group.
    Type of Medium: Online Resource
    ISSN: 0276-3478 , 1098-108X
    URL: Issue
    URL: Article
    DOI: 10.1002/eat.v54.2
    DOI: 10.1002/eat.23425
    Language: English
    Publisher: Wiley
    Publication Date: 2021
    detail.hit.zdb_id: 1492880-2
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  • 4
    Online Resource
    Online Resource
    S3270 Paraquat Poisoning: Esophageal Injury Spectrum at a Tertiary Care Centre
    Ovid Technologies (Wolters Kluwer Health) ; 2021
    In:  American Journal of Gastroenterology Vol. 116, No. 1 ( 2021-10), p. S1347-S1348
    Details
    In: American Journal of Gastroenterology, Ovid Technologies (Wolters Kluwer Health), Vol. 116, No. 1 ( 2021-10), p. S1347-S1348
    Type of Medium: Online Resource
    ISSN: 0002-9270 , 1572-0241
    URL: Article
    DOI: 10.14309/01.ajg.0000786612.51329.89
    RVK:
    XA 18920
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2021
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  • 5
    Online Resource
    Online Resource
    Is it a real balance in hemostasis?
    Elsevier BV ; 2021
    In:  Journal of Thrombosis and Haemostasis Vol. 19, No. 3 ( 2021-03), p. 867-868
    Details
    In: Journal of Thrombosis and Haemostasis, Elsevier BV, Vol. 19, No. 3 ( 2021-03), p. 867-868
    Type of Medium: Online Resource
    ISSN: 1538-7836
    URL: Article
    DOI: 10.1111/jth.15193
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2021
    detail.hit.zdb_id: 2099291-9
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  • 6
    Online Resource
    Online Resource
    Self-reported perceived stress, depression, and generalized anxiety disorder among Kathak dancers and physically active non-dancers of North India
    Frontiers Media SA ; 2023
    In:  Frontiers in Psychology Vol. 14 ( 2023-4-27)
    Details
    In: Frontiers in Psychology, Frontiers Media SA, Vol. 14 ( 2023-4-27)
    Abstract: The aim of the present paper was to study the various common mental disorders in a sample of Kathak dancers and non-dancers of North India. 206 female Kathak dancers and 235 healthy controls, aged 18–45 years completed questionnaires assessing perceived stress (PSS-10), depressive symptoms (PHQ-9), and generalized anxiety (GAD-7). Pearson correlations assessed the association between perceived stress, depression, generalized anxiety, age, and years of dancing, and binary logistic regression identified the risk of developing depression and generalized anxiety disorder in Kathak dancers and non-dancers. The prevalence of perceived stress was similar among Kathak dancers and non-dancers. Kathak dancers reported significantly lower depressive symptoms compared to controls. Non-dancers with elevated perceived stress levels were 4 times more likely to report depressive symptoms and 7 times more likely to report anxiety symptoms, relative to dancers. The adjusted odds of reporting depressive symptoms along with generalized anxiety were higher among non-dancers compared to dancers. Kathak can be developed into a very effective psychotherapeutic tool for mitigating the risk of developing depression and generalized anxiety disorder.
    Type of Medium: Online Resource
    ISSN: 1664-1078
    URL: Article
    DOI: 10.3389/fpsyg.2023.1114377
    Language: Unknown
    Publisher: Frontiers Media SA
    Publication Date: 2023
    detail.hit.zdb_id: 2563826-9
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  • 7
    Online Resource
    Online Resource
    Importance of Human Variation and Scientific Inputs in Designing Furniture
    Science Publishing Group ; 2016
    In:  American Journal of Sports Science Vol. 4, No. 1 ( 2016), p. 31-
    Details
    In: American Journal of Sports Science, Science Publishing Group, Vol. 4, No. 1 ( 2016), p. 31-
    Type of Medium: Online Resource
    ISSN: 2330-8559
    URL: Article
    DOI: 10.11648/j.ajss.s.2016040101.16
    Language: English
    Publisher: Science Publishing Group
    Publication Date: 2016
    detail.hit.zdb_id: 2740848-6
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  • 8
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    Online Resource
    Computational screening of FDA approved drugs of fungal origin that may interfere with SARS-CoV-2 spike protein activation, viral RNA replication, and post‐translational modification: a multiple target approach
    Springer Science and Business Media LLC ; 2021
    In:  In Silico Pharmacology Vol. 9, No. 1 ( 2021-04-04)
    Details
    In: In Silico Pharmacology, Springer Science and Business Media LLC, Vol. 9, No. 1 ( 2021-04-04)
    Type of Medium: Online Resource
    ISSN: 2193-9616
    URL: Article
    DOI: 10.1007/s40203-021-00089-8
    Language: English
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2021
    detail.hit.zdb_id: 2702993-1
    SSG: 15,3
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  • 9
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    Online Resource
    Cytomorphological evaluation of enlarged lymph nodes: A tertiary hospital-based study
    General Organization For Teaching Hospitals and Institutes ; 2022
    In:  Journal of Medicine in Scientific Research Vol. 5, No. 1 ( 2022), p. 68-
    Details
    In: Journal of Medicine in Scientific Research, General Organization For Teaching Hospitals and Institutes, Vol. 5, No. 1 ( 2022), p. 68-
    Type of Medium: Online Resource
    ISSN: 2537-091X
    URL: Article
    DOI: 10.4103/jmisr.jmisr_67_21
    Language: English
    Publisher: General Organization For Teaching Hospitals and Institutes
    Publication Date: 2022
    detail.hit.zdb_id: 3043003-3
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  • 10
    Online Resource
    Online Resource
    1347-P: Utility of Fibrosis-4 (FIB-4) and Nonalcoholic Fatty Liver Disease Fibrosis Scores (NFS) for Liver Fibrosis Screening in Asian-Indians with Type 2 Diabetes—A Cross-Sectional Observational Study
    American Diabetes Association ; 2023
    In:  Diabetes Vol. 72, No. Supplement_1 ( 2023-06-20)
    Details
    In: Diabetes, American Diabetes Association, Vol. 72, No. Supplement_1 ( 2023-06-20)
    Abstract: Background: Fibrosis-4 (FIB-4) and the Nonalcoholic fatty liver disease fibrosis score (NFS) are suggested by American Diabetes Association Standard of Care 2023 for Liver fibrosis screening in type 2 diabetes (T2D). Aim: Utility of FIB-4 and NFS to detect liver fibrosis in Asian-Indians with T2D. Methods: This study included a total of 120 patients who underwent NAFLD screening from July 2022 to December 2022, recruited from Liver Clinic of an Endocrine speciality centre. Vibration Controlled Transient Elastography [VCTE (Fibroscan 430 Mini Plus, Echosens, France)] was used. After excluding alcoholics and nondiabetes patients we had total 73 people with T2D and we calculated FIB-4 and NFS for 46 patients. Liver Stiffness measurement (LSM) in KiloPascals (KPa) cut-off values used are - F0 till 7 kPa, F1 is 7 - 10 kPa, F2 is 10 - 13 kPa, F3 is 13 - 16 kPa and F4 is & gt; 16 kPa. FIB-4 and NFS were calculated using https://www.mdcalc.com. Results: The mean age was 54.6 ± 12.4 years, mean body mass index (BMI) was 27.3 ± 3.7 kg/m2 and 14 (30.4%) were women. Overweight seen in 15.2 % (n=7) and obesity in 69.6 % (n=32). The mean values, Serum Albumin (5.1±2.4 g/dl), SGOT (20.7±8.9 U/L), SGPT (24.0 ±15.1 U/L), Platelet Count (2.7±0.8 x 105) Hba1c % (8.8±2.4) and LSM (6.4 ± 2.6 KPa). NFS grades: F0-F2 in 24 (52.2%), indeterminate in 18 (39%) and F3-F4 in 4 (8.7%). FIB-4 grades: F0-F1 in 40 (86.9%) and F2-F3 in 6 (13.1%). But on VCTE as per LSM it was found F0 in 32 (70%), F1 in 9 (19.6%), F2 in 4 (8.7%) and F4 in 1 (2.2%). We noticed that LSM had significant positive correlation with BMI (p=0.001), SGOT (p=0.04) and SGPT (p=0.011) which are components of FIB-4 and NFS but LSM did not significantly correlate with NFS (p=0.96) and FIB-4 score (p=0.79). Conclusions: FIB-4 and NFS may be sub-optimal for screening Fibrosis in Asian-Indians with T2D. BMI can be considered as potential first step to identify at risk for liver fibrosis in T2D. Disclosure K. Ravi Teja: None. S. Chandel: None.
    Type of Medium: Online Resource
    ISSN: 0012-1797
    URL: Article
    DOI: 10.2337/db23-1347-P
    Language: English
    Publisher: American Diabetes Association
    Publication Date: 2023
    detail.hit.zdb_id: 1501252-9
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