In:
American Journal of Veterinary Research, American Veterinary Medical Association (AVMA), Vol. 65, No. 3 ( 2004-03-01), p. 320-326
Abstract:
Objective —To evaluate the use of multifrequency
bioelectrical impedance analysis (MF-BIA) for estimating total body water (TBW), extracellular fluid
volume (ECFV), and intracellular fluid volume (ICFV) in horses. Animals —9 healthy mares. Procedure —TBW and ECFV were measured by use
of deuterium oxide and sodium bromide dilution techniques, respectively. Intracellular fluid volume was
calculated as the difference between TBW and ECFV. Concurrently, MF-BIA recordings were obtained by
use of 4 anatomic electrode positions and 3 measurements of length. Models for MF-BIA data were
created for all combinations of length and anatomic electrode position. Models were evaluated to determine
the position-length configuration that provided the most consistent estimates of TBW, ECFV, and
ICFV, compared with values determined by use of the dilution techniques. Results —Positioning electrodes over the ipsilateral
carpus and tarsus and use of height at the tuber sacrale for length provided the closest estimate
between values for TBW, ECFV, and ICFV predicted by use of MF-BIA and measured values obtained by dilutional
techniques. This model had the narrowest 95% limits of agreement. Conclusions and Clinical Relevance —MF-BIA
techniques have been used to predict changes in TBW, ECFV, and ICFV in healthy and diseased
humans. Results reported in this study provide an equine-specific model to serve as the basis for further
evaluation of MF-BIA in horses with altered fluid states. The MF-BIA techniques have a number of
potential applications for use in horses, including evaluation of exercise physiology, pharmacologic
studies, and critical-care management. ( Am J Vet Res 2004;65:320–326)
Type of Medium:
Online Resource
ISSN:
0002-9645
DOI:
10.2460/ajvr.2004.65.320
Language:
Unknown
Publisher:
American Veterinary Medical Association (AVMA)
Publication Date:
2004
detail.hit.zdb_id:
2056942-7
SSG:
22
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