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  • 1
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    Online Resource
    Mass treatment for intestinal helminthisis control in an Amazonian endemic area in Brazil
    FapUNIFESP (SciELO) ; 2006
    In:  Revista do Instituto de Medicina Tropical de São Paulo Vol. 48, No. 4 ( 2006-08), p. 189-195
    Details
    In: Revista do Instituto de Medicina Tropical de São Paulo, FapUNIFESP (SciELO), Vol. 48, No. 4 ( 2006-08), p. 189-195
    Abstract: O presente trabalho objetivou avaliar a prevalência e o papel de um tratamento em massa das helmintíases intestinais em Santa Isabel do Rio Negro, Estado do Amazonas, Brasil. Foi realizado em 2002 um estudo seccional, incluindo inquérito copro-parasitológico, objetivando a obtenção das prevalências das parasitoses intestinais e dados sobre as condições sanitárias do local, estudando-se uma amostra de 308 indivíduos. Em 2003 foi realizada intervenção para tratamento em massa das helmintíases intestinais com administração de albendazol (ou mebendazol para crianças entre 12 e 24 meses) na sede do município, alcançando-se 83% de cobertura. Novo inquérito copro-parasitológico foi realizado em 2004, para comparação das prevalências antes a após o tratamento. As prevalências das infecções por Ascaris lumbricoides, Trichuris trichiura e ancilostomídeos foram 48%, 27% e 21%, respectivamente em 2002. Em 2004 observou-se redução significativa das infecções por Ascaris lumbricoides (p 〈 0,05; OR / 95% IC = 0,44 / 0,30 - 0,65), Trichuris trichiura (p 〈 0,05; OR / 95% IC = 0,37 / 0,22 - 0,62), ancilostomídeos (p 〈 0,05; OR / 95% IC = 0,03 / 0,01 - 0,15) e poliparasitismo por helmintos intestinais (p 〈 0,05; OR / 95% IC = 0,16 / 0,08 - 0,32). Foi também observada redução da prevalência de infecção por Entamoeba histolytica/dispar (p 〈 0,05; OR / 95% CI = 0,30 / 0,19 - 0,49). Concluiu-se que o tratamento em massa pode auxiliar o controle das helmintíases intestinais, porém ações governamentais em infraestrutura urbana e educação são essenciais para uma redução sustentada das prevalências destas infecções.
    Type of Medium: Online Resource
    ISSN: 0036-4665
    URL: Article
    DOI: 10.1590/S0036-46652006000400003
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2006
    detail.hit.zdb_id: 2017173-0
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  • 2
    Online Resource
    Online Resource
    Aspectos clínicos da tuberculose pulmonar em idosos atendidos em hospital universitário do Rio de Janeiro, RJ, Brasil
    FapUNIFESP (SciELO) ; 2007
    In:  Jornal Brasileiro de Pneumologia Vol. 33, No. 6 ( 2007-12), p. 699-706
    Details
    In: Jornal Brasileiro de Pneumologia, FapUNIFESP (SciELO), Vol. 33, No. 6 ( 2007-12), p. 699-706
    Abstract: OBJECTIVE: To evaluate clinical aspects and the diagnosis of pulmonary tuberculosis (PT) in the aged. METHODS: We compared 117 patients over 60 years of age (elderly group) and 464 patients aged 15 to 49 years old (nonelderly group) treated at the Thoracic Diseases Institute of the Federal University of Rio de Janeiro, from 1980 to 1996. RESULTS: Previous history of PT was predominant in the elderly group (OR = 2.09; 95% CI = 1.26-3.45; p = 0.002), whereas household contact with PT was predominant in the nonelderly group (OR = 0.26; 95% CI = 0.10-0.66; p = 0.002). Mean time for diagnosis was 90 days in the elderly group and 60 days in the nonelderly group. In the elderly group, dyspnea (OR = 1.64; 95% CI = 1.06-2.53; p = 0.018) and weight loss (OR = 1.66; 95% CI = 1.01-2.82; p = 0.047) were predominant. In the nonelderly group, hemoptysis (OR = 0.51; 95% CI = 0.32-0.81; p = 0.002), chest pain (OR = 0.62; 95% CI = 0.40-0.97; p = 0.027) and fever (OR = 0.55; 95% CI = 0.35-0.86; p = 0.006) were more common. The most common radiological abnormalities were infiltrates and cavitations. Bilateral involvement was more common in the elderly patients (OR = 1.76; 95% CI = 1.12-2.78; p = 0.009). There were no differences between the two groups regarding positivity for Mycobacterium tuberculosis identified through tuberculin skin testing, sputum smear microscopy and culture. CONCLUSIONS: There are few clinical and laboratory differences between the age groups. The delayed diagnosis in the elderly group can be explained by the low clinical suspicion in these patients.
    Type of Medium: Online Resource
    ISSN: 1806-3713
    URL: Article
    DOI: 10.1590/S1806-37132007000600014
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2007
    detail.hit.zdb_id: 2223157-2
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  • 3
    Online Resource
    Online Resource
    Efeito do incentivo alimentício sobre o desfecho do tratamento de pacientes com tuberculose em uma unidade primária de saúde no município de Duque de Caxias, Rio de Janeiro
    FapUNIFESP (SciELO) ; 2009
    In:  Jornal Brasileiro de Pneumologia Vol. 35, No. 10 ( 2009-10), p. 992-997
    Details
    In: Jornal Brasileiro de Pneumologia, FapUNIFESP (SciELO), Vol. 35, No. 10 ( 2009-10), p. 992-997
    Abstract: OBJECTIVE: To evaluate the effect that the distribution of food baskets to tuberculosis (TB) patients has on treatment outcomes at a primary health care clinic. METHODS: Retrospective comparative study of the medical and social aspects of 142 patients at a primary health care clinic in the city of Duque de Caxias, Brazil. The patients were divided into two groups: the first group included 68 patients treated with standard regimens (between September of 2001 and December of 2003); and the second group included 74 patients treated with the same regimens but also receiving food baskets on a monthly basis (between January of 2004 and July of 2006). RESULTS: The statistical comparison between the two groups revealed that the cure rate was higher in the group receiving the food baskets (87.1% vs. 69.7%), whereas the rate of noncompliance was markedly lower (12.9% vs. 30.3%). CONCLUSIONS: The results indicate that the distribution of food baskets can be a useful strategy to improve compliance with TB treatment at primary health care clinics.
    Type of Medium: Online Resource
    ISSN: 1806-3713
    URL: Article
    DOI: 10.1590/S1806-37132009001000008
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2009
    detail.hit.zdb_id: 2223157-2
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  • 4
    Online Resource
    Online Resource
    Análise do tratamento da tuberculose pulmonar em idosos de um hospital universitário do Rio de Janeiro, RJ, Brasil
    FapUNIFESP (SciELO) ; 2007
    In:  Jornal Brasileiro de Pneumologia Vol. 33, No. 6 ( 2007-12), p. 691-698
    Details
    In: Jornal Brasileiro de Pneumologia, FapUNIFESP (SciELO), Vol. 33, No. 6 ( 2007-12), p. 691-698
    Abstract: OBJECTIVE: To describe the clinical and therapeutic aspects of pulmonary tuberculosis and compare the adverse effects of the treatment and its outcome in elderly and nonelderly patients. METHODS: This was a case-control study of 117 elderly individuals (over the age of 60 years) and 464 nonelderly individuals (aged 15-49 years). All subjects presented pulmonary tuberculosis that had been diagnosed and treated at the Thoracic Diseases Institute of the Federal University of Rio de Janeiro between 1980 and 1996. RESULTS: In the elderly group, pulmonary tuberculosis was found to be correlated with diabetes (OR = 3.98; 95% CI = 2.07-7.65; p = 0.001), lung disease (OR = 7.24; 95% CI = 3.64-14.46; p = 0.001) and heart disease (OR = 5.86; 95% CI = 2.88-11.95; p = 0.001). Smoking (OR = 2.07; 95% CI = 1.26-3.42; p = 0.002) and alcohol abuse (OR = 1.63; 95% CI = 1.01-2.68; p = 0.041) were also more common in the elderly group. In the elderly group, the treatment more frequently resulted in adverse reactions (OR = 1.62; 95% CI = 1.04-2.54; p = 0.024), especially gastrointestinal reactions (OR = 1.64; 95% CI = 1.01-2.77; p = 0.047), and treatment efficacy was lower: cure rate, 51%; mortality rate, 24%. Treatment adherence was low (approximately 77%) in both groups. CONCLUSIONS: In the elderly group, adverse reactions were more common, treatment outcomes were less favorable, there was a greater frequency of clinical complications and deaths related to drug toxicity, and the prevalence of concomitant diseases was higher.
    Type of Medium: Online Resource
    ISSN: 1806-3713
    URL: Article
    DOI: 10.1590/S1806-37132007000600013
    Language: Unknown
    Publisher: FapUNIFESP (SciELO)
    Publication Date: 2007
    detail.hit.zdb_id: 2223157-2
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