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  • 1
    Online Resource
    Online Resource
    Reporting and Analysis of Race in Vascular Surgery Research
    Elsevier BV ; 2023
    In:  Journal of Vascular Surgery Vol. 78, No. 3 ( 2023-09), p. e48-e49
    Details
    In: Journal of Vascular Surgery, Elsevier BV, Vol. 78, No. 3 ( 2023-09), p. e48-e49
    Type of Medium: Online Resource
    ISSN: 0741-5214
    URL: Article
    DOI: 10.1016/j.jvs.2023.06.130
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 1492043-8
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  • 2
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    Historical redlining and breast cancer treatment and survival among older women in the United States
    Oxford University Press (OUP) ; 2023
    In:  JNCI: Journal of the National Cancer Institute Vol. 115, No. 6 ( 2023-06-08), p. 652-661
    Details
    In: JNCI: Journal of the National Cancer Institute, Oxford University Press (OUP), Vol. 115, No. 6 ( 2023-06-08), p. 652-661
    Abstract: Breast cancer (BC) is the most common cancer among US women, and institutional racism is a critical cause of health disparities. We investigated impacts of historical redlining on BC treatment receipt and survival in the United States. Methods Home Owners’ Loan Corporation (HOLC) boundaries were used to measure historical redlining. Eligible women in the 2010-2017 Surveillance, Epidemiology, and End Results–Medicare BC cohort were assigned a HOLC grade. The independent variable was a dichotomized HOLC grade: A and B (nonredlined) and C and D (redlined). Outcomes of receipt of various cancer treatments, all-cause mortality (ACM), and BC-specific mortality (BCSM) were analyzed using logistic or Cox models. Indirect effects by comorbidity were examined. Results Among 18 119 women, 65.7% resided in historically redlined areas (HRAs), and 32.6% were deceased at a median follow-up of 58 months. A larger proportion of deceased women resided in HRAs (34.5% vs 30.0%). Of all deceased women, 41.6% died of BC; a larger proportion resided in HRAs (43.4% vs 37.8%). Historical redlining is a statistically significant predictor of poorer survival after BC diagnosis (hazard ratio = 1.09, 95% confidence interval [CI] = 1.03 to 1.15 for ACM, and hazard ratio = 1.26, 95% CI = 1.13 to 1.41 for BCSM). Indirect effects via comorbidity were identified. Historical redlining was associated with a lower likelihood of receiving surgery (odds ratio = 0.74, 95% CI = 0.66 to 0.83, and a higher likelihood of receiving palliative care odds ratio = 1.41, 95% CI = 1.04 to 1.91). Conclusion Historical redlining is associated with differential treatment receipt and poorer survival for ACM and BCSM. Relevant stakeholders should consider historical contexts when designing and implementing equity-focused interventions to reduce BC disparities. Clinicians should advocate for healthier neighborhoods while providing care.
    Type of Medium: Online Resource
    ISSN: 0027-8874 , 1460-2105
    URL: Article
    DOI: 10.1093/jnci/djad034
    RVK:
    XA 10000
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2023
    detail.hit.zdb_id: 2992-0
    detail.hit.zdb_id: 1465951-7
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  • 3
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    Factors Associated with Hospital Readmission One Year Post-Discharge in Infants with Gastroschisis
    S. Karger AG ; 2023
    In:  Fetal Diagnosis and Therapy
    Details
    In: Fetal Diagnosis and Therapy, S. Karger AG
    Abstract: 〈 b 〉 〈 i 〉 Introduction: 〈 /i 〉 〈 /b 〉 Gastroschisis is the most common congenital abdominal wall defect with a rising prevalence. Infants with gastroschisis are at risk for multiple complications, leading to a potential increased risk for hospital readmission after discharge. We aimed to find the frequency and factors associated with an increased risk of readmission. 〈 b 〉 〈 i 〉 Methods: 〈 /i 〉 〈 /b 〉 A retrospective analysis of infants born with gastroschisis between 2013 and 2019 who received initial surgical intervention and follow-up care in the Children’s Wisconsin health system was performed. The primary outcome was the frequency of hospital readmission within 1 year of discharge. We also compared maternal and infant clinical and demographic variables between those readmitted for reasons related to gastroschisis, and those readmitted for other reasons or not readmitted. 〈 b 〉 〈 i 〉 Results: 〈 /i 〉 〈 /b 〉 Forty of 90 (44%) infants born with gastroschisis were readmitted within 1-year of the initial discharge date, with 33 (37%) of the 90 infants being readmitted due to reasons directly related to gastroschisis. The presence of a feeding tube ( 〈 i 〉 p 〈 /i 〉 & lt; 0.0001), a central line at discharge ( 〈 i 〉 p 〈 /i 〉 = 0.007), complex gastroschisis ( 〈 i 〉 p 〈 /i 〉 = 0.045), conjugated hyperbilirubinemia ( 〈 i 〉 p 〈 /i 〉 = 0.035), and the number of operations during the initial hospitalization ( 〈 i 〉 p 〈 /i 〉 = 0.044) were associated with readmission. Maternal race/ethnicity was the only maternal variable associated with readmission, with Black race being less likely to be readmitted ( 〈 i 〉 p 〈 /i 〉 = 0.003). Those who were readmitted were also more likely to be seen in outpatient clinics and utilize emergency healthcare resources. There was no statistically significant difference in readmission based on socioeconomic factors (all 〈 i 〉 p 〈 /i 〉 & gt; 0.084). 〈 b 〉 〈 i 〉 Conclusion: 〈 /i 〉 〈 /b 〉 Infants with gastroschisis have a high hospital readmission rate, which is associated with a variety of risk factors including complex gastroschisis, multiple operations, and the presence of a feeding tube or central line at discharge. Improved awareness of these risk factors may help stratify patients in need of increased parental counseling and additional follow-up.
    Type of Medium: Online Resource
    ISSN: 1015-3837 , 1421-9964
    URL: Article
    DOI: 10.1159/000531449
    Language: English
    Publisher: S. Karger AG
    Publication Date: 2023
    detail.hit.zdb_id: 1482292-1
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  • 4
    Online Resource
    Online Resource
    Historical redlining and breast cancer survival in the United States: Evidence from the 2010-2017 SEER Medicare linked dataset.
    American Society of Clinical Oncology (ASCO) ; 2022
    In:  Journal of Clinical Oncology Vol. 40, No. 16_suppl ( 2022-06-01), p. 1095-1095
    Details
    In: Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, No. 16_suppl ( 2022-06-01), p. 1095-1095
    Abstract: 1095 Background: Cancer is the second leading cause of morbidity and mortality in the US. Systemic racism is a critical cause of health disparities and historically disadvantaged people experience poor outcomes including poor breast cancer (BC) survival. This study aims to investigate the impact of historical redlining on all-cause and BC-specific survival among older women in the US. Methods: Historic 1930’s Homeowner’s Loan Corporation (HOLC) boundaries and grades were linked to 2010 Census tracts and the 2010-2017 SEER Medicare BC cohort. Women were included if they were 66+ years old at diagnosis, diagnosed with invasive BC, enrolled in Medicare Part A and Part B for 12 months prior to diagnosis to calculate comorbidity, and a Census tract match for HOLC grade. The independent variable was HOLC grade in two categories: A and B(not redlined), and C and D(redlined). The outcomes were all-cause and BC-specific survival, determined by Kaplan Meier Survival curves and both unadjusted and adjusted Cox regression models. End point for censoring was 12/31/2019 (all-cause) and 12/31/2018 (BC-specific). The final models were stratified by age and tumor stage at diagnosis; and adjusted for comorbidity, race and ethnicity, hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2) status, and interaction term between comorbidity and race. Results: Among 10,113 women, 62.8% resided in historically redlined Census tracts. At a mean (+SD) follow-up time of 48.5 (+28.8) months, 28.9% were deceased; 41.6% of which died of BC. Women residing in historically redlined census tracts experienced poorer BC survival (49.8 +28.2 months) than those residing in non-redlined Census tracts (57.8 +30.7 months). After controlling for covariates, residing in a historically redlined Census tract remained an independent predictor of higher mortality: HR (95%CI) = 1.11 (1.02, 1.20) and 1.24 (1.011, 1.39) for all-cause mortality and BC-specific mortality, respectively. Conclusions: Residing in a formerly redlined Census tract at the time of BC diagnosis is associated with worse all-cause and BC-specific mortality, even after stratifying/adjusting for important patient and tumor characteristics. Public health and government agencies stakeholders should consider historical contexts when designing and implementing equity-focused community and clinical interventions targeted at mitigating and reducing BC disparities and improving health equity.
    Type of Medium: Online Resource
    ISSN: 0732-183X , 1527-7755
    URL: Article
    DOI: 10.1200/JCO.2022.40.16_suppl.1095
    RVK:
    XA 52760
    RVK:
    XA 10000
    Language: English
    Publisher: American Society of Clinical Oncology (ASCO)
    Publication Date: 2022
    detail.hit.zdb_id: 2005181-5
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  • 5
    Online Resource
    Online Resource
    MON-018 Effectiveness of the National Diabetes Prevention Program in Latino Men
    The Endocrine Society ; 2019
    In:  Journal of the Endocrine Society Vol. 3, No. Supplement_1 ( 2019-04-15)
    Details
    In: Journal of the Endocrine Society, The Endocrine Society, Vol. 3, No. Supplement_1 ( 2019-04-15)
    Type of Medium: Online Resource
    ISSN: 2472-1972
    URL: Article
    DOI: 10.1210/js.2019-MON-018
    Language: English
    Publisher: The Endocrine Society
    Publication Date: 2019
    detail.hit.zdb_id: 2881023-5
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  • 6
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    Characterizing the impact of SARS-CoV-2 reinfection on surgical outcomes
    Oxford University Press (OUP) ; 2024
    In:  British Journal of Surgery Vol. 111, No. 1 ( 2024-01-03)
    Details
    In: British Journal of Surgery, Oxford University Press (OUP), Vol. 111, No. 1 ( 2024-01-03)
    Type of Medium: Online Resource
    ISSN: 0007-1323 , 1365-2168
    URL: Article
    DOI: 10.1093/bjs/znad436
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2024
    detail.hit.zdb_id: 2006309-X
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  • 7
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    Online Resource
    Isolation and survival: The impact of local and MSA isolation on survival among non-Hispanic Black women diagnosed with breast cancer in the United States using a SEER-Medicare cohort
    Elsevier BV ; 2023
    In:  Health & Place Vol. 83 ( 2023-09), p. 103090-
    Details
    In: Health & Place, Elsevier BV, Vol. 83 ( 2023-09), p. 103090-
    Type of Medium: Online Resource
    ISSN: 1353-8292
    URL: Article
    DOI: 10.1016/j.healthplace.2023.103090
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 2006340-4
    SSG: 14
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  • 8
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    Online Resource
    Maximal Aortic Diameter at Zone 3 Predicts Negative Remodeling After Initial Type a Dissection Repair
    Elsevier BV ; 2023
    In:  Journal of Vascular Surgery Vol. 77, No. 6 ( 2023-06), p. e254-
    Details
    In: Journal of Vascular Surgery, Elsevier BV, Vol. 77, No. 6 ( 2023-06), p. e254-
    Type of Medium: Online Resource
    ISSN: 0741-5214
    URL: Article
    DOI: 10.1016/j.jvs.2023.03.359
    Language: English
    Publisher: Elsevier BV
    Publication Date: 2023
    detail.hit.zdb_id: 1492043-8
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  • 9
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    Take charge during treatment: A planned exercise protocol to evaluate disparities and cardiovascular outcomes in Black and White patients with breast cancer undergoing treatment.
    American Society of Clinical Oncology (ASCO) ; 2022
    In:  Journal of Clinical Oncology Vol. 40, No. 16_suppl ( 2022-06-01), p. TPS12138-TPS12138
    Details
    In: Journal of Clinical Oncology, American Society of Clinical Oncology (ASCO), Vol. 40, No. 16_suppl ( 2022-06-01), p. TPS12138-TPS12138
    Abstract: TPS12138 Background : Cardiotoxicity is a significant challenge associated with common first-line breast cancer (BC) chemotherapy (CTx) treatments including anthracyclines (AC) and targeted therapies, such as anti-Her-2 therapy. For targeted therapies, cardiac complications typically resolve once treatment is completed or stopped. For ACs, treatment may lead to permanent long term cardiac damage, and elevated risk for major adverse cardiovascular events (MACE). Black/African American (B/AA) women are at higher risk for AC-based cardiotoxicity compared to Non-Hispanic White (NHW) women. To date, most efforts have targeted managing and defining mechanisms of large vessels and cardiac damage. However, impaired microvascular function, a powerful but clinically underused predictor of future MACE, may also be implicated. Extensive evidence shows that exercise interventions reduce systemic inflammation and possibly MACE. However, few cardio-oncology studies have utilized exercise to mitigate cardiotoxicity, and none have quantified microvascular endothelial function. A further gap in cardio-oncology research is a paucity of studies focused on understanding and addressing disparities. This research project aims to 1) test the feasibility and efficacy of an exercise intervention designed to mitigate the effects of CTx, Take Charge during Treatment (TCT) and 2) examine the influence of socio-ecological factors on endothelial function in response to an exercise intervention. Methods: B/AA (n=50) and NHW (n=50) women diagnosed with non-metastatic BC, scheduled to receive AC and/or anti-HER-2 therapy, will be recruited and randomized to participate in the TCT intervention or usual care (NCT05223322). TCT is a virtual exercise coaching program with weekly coaching sessions, six of which include supervised exercise. Assessments to assess socio-ecologic and vascular outcomes are presented in the Table. Assessments will be completed prior to treatment (T1), after treatment completion (18-24 weeks, T2), and 12-months post treatment (T3). Clinical trial information: NCT05223322. [Table: see text]
    Type of Medium: Online Resource
    ISSN: 0732-183X , 1527-7755
    URL: Article
    DOI: 10.1200/JCO.2022.40.16_suppl.TPS12138
    RVK:
    XA 52760
    RVK:
    XA 10000
    Language: English
    Publisher: American Society of Clinical Oncology (ASCO)
    Publication Date: 2022
    detail.hit.zdb_id: 2005181-5
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  • 10
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    Abstract P5-14-15: Examining inequities related to inpatient hospital length of stay for breast cancer patients: A retrospective study during the COVID-19 pandemic
    American Association for Cancer Research (AACR) ; 2022
    In:  Cancer Research Vol. 82, No. 4_Supplement ( 2022-02-15), p. P5-14-15-P5-14-15
    Details
    In: Cancer Research, American Association for Cancer Research (AACR), Vol. 82, No. 4_Supplement ( 2022-02-15), p. P5-14-15-P5-14-15
    Abstract: Purpose: In the state of Wisconsin, breast cancer patients from African American (AAs) communities have lower survival rates compared to their Caucasian counterparts. Multiple inequities related to sociodemographic factors, delays in diagnosis, advanced disease stage at presentation and presence of comorbidities including higher body mass index (BMI) contribute to these disparities, many of which have only widened during the COVID-19 pandemic. This study examined specific factors related to prolonged hospital length of stay (LOS) for breast cancer patients admitted to inpatient units during the pandemic. Methods: This analysis includes initial CY20 LOS medical record data for hospitalized patients 18 years and older with a diagnosis of breast cancer from 1/1/2020-12/31/2020. Supplemental data included disease registry and diagnostic data, and SES data determined by patient zip code. Poisson regression models with robust standard errors were used to compare the LOS index (LOSi) between groups of patients based on race, SES group, primary payer, and BMI. Results: A total of 272 patients with breast cancer that were admitted to inpatient oncology units were identified. Demographics included White (72.4%), Black (22.4%), and others (5.1%). Other characteristics included: low SES (8.8%), medium- low (9.5%), medium (15.4%), medium-high (11.0%), high SES (4.4%), and others (non-Milwaukee county) (50.7%),Medicaid (8.8%), Medicare (61.3%), Managed care (29.0%), and others (0.73%). Body mass varied among the patients; underweight (0.36%), overweight (30.8%), obese (41.5%). There were significant differences in LOSi: Black (LOSi=1.24, p=0.01), medium-low SES (LOSi=1.46, p=0.02), Medicaid (LOSi=1.40, p=0.00), underweight (LOSi=1.66, p=0.00), and overweight (LOSi=1.23, p = 0.01) patients had slightly longer LOSi, with LOSi ratio above 1. Conclusion: This study shows how patient-specific factors such as race, SES, primary payer, and BMI contribute to inpatient LOS for breast cancer patients. Healthcare systems may benefit by addressing indicators and patients’ factors to reduce hospital LOS, and ultimately healthcare costs. Citation Format: Sailaja Kamaraju, Bethany Canales, Tamiah Wright, John Charlson, Aniko Szabo, Thomas Wetzel, Steve Power, Grace Campbell. Examining inequities related to inpatient hospital length of stay for breast cancer patients: A retrospective study during the COVID-19 pandemic [abstract]. In: Proceedings of the 2021 San Antonio Breast Cancer Symposium; 2021 Dec 7-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2022;82(4 Suppl):Abstract nr P5-14-15.
    Type of Medium: Online Resource
    ISSN: 0008-5472 , 1538-7445
    URL: Article
    DOI: 10.1158/1538-7445.SABCS21-P5-14-15
    RVK:
    XA 36000
    RVK:
    XA 10000
    Language: English
    Publisher: American Association for Cancer Research (AACR)
    Publication Date: 2022
    detail.hit.zdb_id: 2036785-5
    detail.hit.zdb_id: 1432-1
    detail.hit.zdb_id: 410466-3
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