In:
Advanced Synthesis & Catalysis, Wiley, Vol. 363, No. 22 ( 2021-11-23), p. 5085-5091
Abstract:
Substrate‐controlled cascade reactions between α,β‐unsaturated aldehydes or their analogues and 2,4‐dinitrobenzyl chloride in the presence of a chiral secondary amine as the catalyst and base were developed, to obtain a broad spectrum of α‐benzylated enals and enantioenriched cyclopropane‐fused chroman‐2‐one derivatives. The cyclopropane‐tethered iminium ion clearly served as a key intermediate in these reactions to trigger stereochemical outcomes, one of which was supported by a control experiment. magnified image
Type of Medium:
Online Resource
ISSN:
1615-4150
,
1615-4169
DOI:
10.1002/adsc.v363.22
DOI:
10.1002/adsc.202100613
Language:
English
Publisher:
Wiley
Publication Date:
2021
detail.hit.zdb_id:
2041384-1
detail.hit.zdb_id:
2033084-4
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