In:
Journal of the International Association of Physicians in AIDS Care, SAGE Publications, Vol. 11, No. 1 ( 2012-02), p. 26-33
Abstract:
Background: The role of antiretroviral drugs in the prevention of mother-to-child transmission (PMTCT) of HIV is well known. The objective of this study is to explore how nonchemoprophylactic factors, including infant feeding practices, mother’s HIV status disclosure, mode and place of delivery, infant gender, and maternal age, are related to MTCT. Methods: The study analyzed program data of DNA polymerase chain reaction (PCR) results from dried blood spot samples and selected client information from perinatally exposed infants aged 0 to 12 months. Results: A total of 8237 samples were analyzed. In all, 84% of the mothers ever breast-fed their children. In instances where both mother and baby received intervention, the transmission rates of HIV were higher among those who are still breast-feeding after 6 to 12 months. Disclosure, location, and mode of delivery did not have an effect on the transmission rates of HIV when both mother and baby received prophylaxis. Conclusion: Nonchemoprophylaxis factors, especially breast-feeding, play a key role in perinatal transmission of HIV.
Type of Medium:
Online Resource
ISSN:
1545-1097
DOI:
10.1177/1545109710393308
Language:
English
Publisher:
SAGE Publications
Publication Date:
2012
detail.hit.zdb_id:
2709037-1
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