In:
PLOS ONE, Public Library of Science (PLoS), Vol. 16, No. 2 ( 2021-2-22), p. e0246452-
Abstract:
Anopheles mosquitoes are colonized by diverse microorganisms that may impact on host biology and vectorial capacity. Eukaryotic symbionts such as fungi have been isolated from Anopheles , but whether they are stably associated with mosquitoes and transmitted transstadially across mosquito life stages or to subsequent generations remains largely unexplored. Here, we show that a Leptosphaerulina sp. fungus isolated from the midgut of An . gambiae can be stably associated with An . gambiae host and that it imposes low fitness cost when re-introduced through co-feeding. This fungus is transstadially transmitted across An . gambiae developmental stages and to their progeny. It is present in field-caught larvae and adult mosquitoes at moderate levels across geographical regions. We observed that Leptosphaerulina sp. induces a distinctive melanotic phenotype across the developmental stages of mosquito. As a eukaryotic symbiont that is stably associated with An . gambiae Leptosphaerulina sp. can be explored for paratransgenesis.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0246452
DOI:
10.1371/journal.pone.0246452.g001
DOI:
10.1371/journal.pone.0246452.g002
DOI:
10.1371/journal.pone.0246452.g003
DOI:
10.1371/journal.pone.0246452.g004
DOI:
10.1371/journal.pone.0246452.t001
DOI:
10.1371/journal.pone.0246452.t002
DOI:
10.1371/journal.pone.0246452.s001
DOI:
10.1371/journal.pone.0246452.s002
DOI:
10.1371/journal.pone.0246452.s003
DOI:
10.1371/journal.pone.0246452.s004
DOI:
10.1371/journal.pone.0246452.s005
DOI:
10.1371/journal.pone.0246452.r001
DOI:
10.1371/journal.pone.0246452.r002
DOI:
10.1371/journal.pone.0246452.r003
DOI:
10.1371/journal.pone.0246452.r004
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2021
detail.hit.zdb_id:
2267670-3
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