In:
ISRN Medicinal Chemistry, Hindawi Limited, Vol. 2013 ( 2013-09-10), p. 1-11
Abstract:
A series of pyrano[4,3-b][1] benzopyranones ( 7a–t ) were synthesized through hetero-Diels-Alder reaction of substituted 3-formylchromones ( 5 ) with enol ethers ( 6 ), characterized by IR, 1 H NMR, 13 C NMR, and mass spectral techniques. All the compounds were evaluated for antimicrobial activity against various bacterial and fungal strains, found to possess significant inhibitory potential, particularly, compounds bearing electron withdrawing group - fluoro such as 7i and 7h . Compounds were also tested and displayed a significant inhibitory potential against methicillin-resistant Staphylococcus aureus (MRSA).
Type of Medium:
Online Resource
ISSN:
2314-629X
Language:
English
Publisher:
Hindawi Limited
Publication Date:
2013
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