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  • 1
    Online Resource
    Online Resource
    Volgograd State University ; 2014
    In:  Vestnik Volgogradskogo gosudarstvennogo universiteta. Serija 1. Mathematica. Physica , No. 6 ( 2014-12-22), p. 18-28
    In: Vestnik Volgogradskogo gosudarstvennogo universiteta. Serija 1. Mathematica. Physica, Volgograd State University, , No. 6 ( 2014-12-22), p. 18-28
    Type of Medium: Online Resource
    ISSN: 2222-8896
    Uniform Title: Кинематические свойства толстого диска Галактики по данным каталога Breddles et al.
    URL: Issue
    Language: Unknown
    Publisher: Volgograd State University
    Publication Date: 2014
    detail.hit.zdb_id: 2920051-9
    Location Call Number Limitation Availability
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  • 2
    Online Resource
    Online Resource
    ECO-Vector LLC ; 2020
    In:  Epidemiology and Infectious Diseases Vol. 25, No. 1 ( 2020-10-02), p. 35-40
    In: Epidemiology and Infectious Diseases, ECO-Vector LLC, Vol. 25, No. 1 ( 2020-10-02), p. 35-40
    Abstract: Bacterial vacuolated intracellular parasites, such as Salmonella spp. and Brucella spp., possess the ability to cause persistent, long-life chronic infection during which the microbe continues to replicate inside the host organism in spite of the development of an immune response. Such bacteria develop a strategy to evade the immune response, which plays a key role in the development of chronic infection. The implementation of this strategy is aimed at inhibiting the action of factors of innate immunity. In brucella, this process is mediated by the noncanonical structure of lipopolysaccharide (LPS), as a result of which the pathogen is not recognized by the cells of innate immunity, as well as by the functioning of T4CC, the effector proteins of which block the development of the inflammatory response. The strategy of S. Typhi is realized via the expression of genes of pathogenicity island 7 encoding Vi-antigen and genotoxin. Vi-antigen inhibits recognition of the microbe by cells of the innate immune system. Typhoid genotoxin causes the death of immune cells. Brucella realizes this strategy via the noncanonical structure of LPS and T4SS, effector proteins of which block the development of inflammation. Alternative activated macrophages appear during chronic infection caused by both pathogens. These microbes are able to regulate the metabolism of macrophages according to their needs while persisting in them. A review of the sources of information on this problem allows us to conclude that both the causative agent of typhoid fever S. Typhi and the causative agents of brucellosis use the same strategies for the development of a chronic infectious process, but the implementation of these strategies is carried out specifically.
    Type of Medium: Online Resource
    ISSN: 2411-3026 , 1560-9529
    URL: Issue
    Language: Unknown
    Publisher: ECO-Vector LLC
    Publication Date: 2020
    Location Call Number Limitation Availability
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  • 3
    Online Resource
    Online Resource
    Tambov State University - G.R. Derzhavin ; 2022
    In:  Tambov University Review. Series: Humanities , No. 6 ( 2022), p. 1545-1551
    In: Tambov University Review. Series: Humanities, Tambov State University - G.R. Derzhavin, , No. 6 ( 2022), p. 1545-1551
    Abstract: The difficulties that arise in the formation of tolerant relationships among the rural youth and people with disabilities on the basis of the municipality of the village of Ermolovka and the House of Culture of the Liskinsky district of the Voronezh region are analyzed. The purpose of the study: the formation of respectful relationships between the rural youth, namely to persons with disabilities and the identification of effective forms of work by means of physical culture and sports with the use of Olympic values. Research objectives: 1) provide information to the younger generation of the village about Olympic values, adaptive sports and the movement of the Special Olympics; 2) identify highly effective means, forms and methods of tolerant relationship of young rurals to people with disabilities using Olympic values; 3) to develop and experimentally substantiate the method of applying various organizational and methodical ways and methods to increase the level of knowledge on Olympic education of the younger generation, their respectful attitude to persons with disabilities and involvement in the field of physical culture and sports. The study revealed that as a result of the purposeful use of Olympic education funds, the level of tolerant relationship between young rurals and people with disabilities has increased, and there has also been a big jump in the interest of the rural young generation in physical education and a healthy lifestyle.
    Type of Medium: Online Resource
    ISSN: 1810-0201
    Uniform Title: Формирование толерантности у сельской молодежи к лицам с ограниченными возможностями здоровья на основе олимпийских ценностей (на примере движения Специальной Олимпиады)
    URL: Issue
    Language: Unknown
    Publisher: Tambov State University - G.R. Derzhavin
    Publication Date: 2022
    detail.hit.zdb_id: 3105380-4
    SSG: 7,41
    Location Call Number Limitation Availability
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