In:
The Open Orthopaedics Journal, Bentham Science Publishers Ltd., Vol. 9, No. 1 ( 2015-7-31), p. 367-371
Abstract:
Trauma is a major public health problem worldwide. Infectious complications, sepsis, and multiple organ
dysfunction syndrome (MODS) remain important causes for morbidity and mortality in patients who survive the initial trauma. There is increasing evidence for the role of genetic variation in the innate immune system on infectious
complications in severe trauma patients. We describe a trauma patient with multiple infectious complications caused by multiple micro-organisms leading to prolonged hospital stay with numerous treatments. This patient had multiple single
nucleotide polymorphisms (SNPs) in the MBL2, MASP2, FCN2 and TLR2 genes, most likely contributing to increased
susceptibility and severity of infectious disease.
Type of Medium:
Online Resource
ISSN:
1874-3250
DOI:
10.2174/1874325001509010367
Language:
English
Publisher:
Bentham Science Publishers Ltd.
Publication Date:
2015
detail.hit.zdb_id:
2395994-0
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