In:
Adipositas - Ursachen, Folgeerkrankungen, Therapie, Georg Thieme Verlag KG, Vol. 12, No. 01 ( 2018-02), p. 32-37
Abstract:
Only a few studies have investigated the influence of weight loss on metabolic parameters in overweight and obese children. This research has analyzed metabolic parameters before and after attending a one year interdisciplinary life style intervention (KICK). 373 children (47,2 % boys) with overweight and obesity (BMI 〉 90 percentile; BMI SDS 2,43 ± 0,43 mean ± SD) have started, at the age of 11,9 ± 2,3 years, the KICK-program. Metabolic (total, HDL-, and LDL-cholesterol, triglycerides, fasting glucose and HbA1c) and somatometric parameters as well as the systolic and diastolic blood pressure have been recorded at the beginning of the program as well as at the follow-up check. At follow-up (1,4 ± 0,4 years), patients have reached a BMI-SDS difference of 0,78 ± 0,41 (P 〈 0,001). The success of weight loss has been classified as follow: significant (BMI-SDS-Delta ≤-0,5) 60 patients (46,7 % boys); moderate (BMI-SDS-Delta ≤-0,2 or 〉 -0,5) 96 patients (42,7 % boys); no change (BMI-SDS-Delta 〉 -0,2 and 〈 0,2) 167 (50,9 % boys) and weight gain (BMI-SDS- Delta ≥0,2) 50 children (44,0 % boys). Although we found a metabolically favorable trend for all lipid parameters (all P 〈 0,001) and HbA1c (P = 0,021) in the whole group, these differences were particularly pronounced in the group of children with weight loss. The HbA1c changed significantly in the whole group compared to the initial value: HbA1c 5,2 ± 0,7 % vs. HbA1c 5,3 ± 0,3 % (P 〈 0,05). The fasting glucose value remained unchanged (83,7 ± 7,1 mg/dl vs. 83,5 ± 6,8 mg/dl, P = 0,693). Children who lost weight by the participation in an interdisciplinary life changing program have shown a significant improvement in their atherogenic parameters. This confirms our assumption that even a minor weight loss in children, lowers their risk of comorbidities.
Type of Medium:
Online Resource
ISSN:
1865-1739
,
2567-6334
DOI:
10.1055/s-0038-1636969
Language:
German
Publisher:
Georg Thieme Verlag KG
Publication Date:
2018
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