In:
Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 7, No. 4 ( 1953-04), p. 523-532
Abstract:
In 22 dogs with ventricular tachycardia accompanying myocardial infarction, Nupercaine hydrochloride was found to be a potent suppressor of ectopic impulses. When used alone Nupercaine also produced vomiting and convulsive movements. When combined with morphine, vomiting was eliminated, but convulsions still occurred. When combined with phenobarbital sodium or pentobarbital sodium, the ectopic impulse suppressor action of Nupercaine was enhanced and both vomiting and convulsive movements were prevented. The duration of ectopic impulse suppressor action was significantly greater in the phenobarbital-Nupercaine experiments than in any other group. No deaths occurred.
Type of Medium:
Online Resource
ISSN:
0009-7322
,
1524-4539
DOI:
10.1161/01.CIR.7.4.523
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
1953
detail.hit.zdb_id:
1466401-X
detail.hit.zdb_id:
80099-5
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