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  • 1
    Online Resource
    Online Resource
    Annual population rhythm of Anopheles mosquitoes in Indian subcontinent
    Springer Science and Business Media LLC ; 2010
    In:  Nature Precedings ( 2010-6-24)
    Details
    In: Nature Precedings, Springer Science and Business Media LLC, ( 2010-6-24)
    Type of Medium: Online Resource
    ISSN: 1756-0357
    URL: Article
    DOI: 10.1038/npre.2010.4569
    Language: Unknown
    Publisher: Springer Science and Business Media LLC
    Publication Date: 2010
    detail.hit.zdb_id: 2637018-9
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  • 2
    Online Resource
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    Computational Study Reliability of Diesel Engine through Electrical Assembly
    Penerbit UTHM ; 2021
    In:  The International Journal of Integrated Engineering Vol. 13, No. 6 ( 2021-08-31)
    Details
    In: The International Journal of Integrated Engineering, Penerbit UTHM, Vol. 13, No. 6 ( 2021-08-31)
    Abstract: Diesel engine's complexity is a primary cause of breakdown or inability. Engine failure impacts device performance and thus efficiency. It often increases the cost of maintenance as the system goes down again and again. The main aim of this analysis is therefore to concentrate on aspects of the reliability and availability of diesel locomotive engines. For this reason, a large collection of observations is explored to evaluate the availability output of electrical assembly components. Weibull distribution is then used to analyse the reliability of the system and the rate of failure information that can be used in the rail industry to minimize unforeseen failures and to increase the reliability as well as the availability of diesel locomotives. A comparative study of Weibull distribution with the other distribution has been carried out to show the benefits of the Weibull distribution.
    Type of Medium: Online Resource
    ISSN: 2229-838X , 2600-7916
    URL: Issue
    URL: Journal
    URL: Article
    DOI: 10.30880/ijie.2021.13.06
    DOI: 10.30880/ijie
    DOI: 10.30880/ijie.2021.13.06.015
    Language: Unknown
    Publisher: Penerbit UTHM
    Publication Date: 2021
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  • 3
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    Abstract 10807: Pace-Capture versus No Pace-Capture Guided Ablation for Atrial Fibrillation: Systematic Review and Meta-Analysis
    Ovid Technologies (Wolters Kluwer Health) ; 2021
    In:  Circulation Vol. 144, No. Suppl_1 ( 2021-11-16)
    Details
    In: Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 144, No. Suppl_1 ( 2021-11-16)
    Abstract: Introduction: Radiofrequency catheter ablation through circumferential lesions around pulmonary veins (PVs) ostia has been shown to be effective for treating atrial fibrillation. Arrhythmia recurrence has largely been due to recovery of conduction between PVs and left atrium. Hypothesis: To determine the efficacy of unexcitability to pacing along the ablation line as an endpoint of the PV isolation procedure. Methods: Electronic searches on PubMed, The Cochrane Library, EMBASE, EBSCO, Web of Science, and CINAHL databases from the inception through June 7, 2021was performed. Statistical analysis was performed using meta-package for R version 4.0 and Rstudio version 1.2. The primary outcome was recurrent atrial arrhythmias. Secondary outcomes were procedure time (minutes), fluoroscopic time (minutes), and procedural complications. Results: Three eligible studies consisting of 338 patients (Pace-capture group - 168 and No Pace-capture group - 170) were included in the meta-analysis. There was a statistically significant reduction of recurrent atrial arrhythmias in the Pace-capture group vs. No Pace-capture (21% versus 31%, RR 0.68; 95% CI 0.47 - 0.98; p = 0.04). Procedure duration was significantly longer in the pace group {mean difference (MD) 16, 95% CI 6.96-25.05, p 〈 0.001}; however, fluoroscopy times were not different (MD 2.24, 95% CI -0.27-4.75, p=0.08). No difference in procedural-related complications was noted between the two groups (RR 0.33, 95% CI 0.05-2.10; P=0.24). Conclusions: The endpoint of unexcitability along the ablation line was associated with a reduction in recurrent atrial arrhythmia after PV isolation, but as expected, it did prolong procedure time by ~16 min
    Type of Medium: Online Resource
    ISSN: 0009-7322 , 1524-4539
    URL: Article
    DOI: 10.1161/circ.144.suppl_1.10807
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2021
    detail.hit.zdb_id: 1466401-X
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  • 4
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    Abstract 10836: Outcomes of Biventricular Pacing versus Conventional Pacing (DDD Mode) in Patients with a Normal Left Ventricular Ejection Fraction
    Ovid Technologies (Wolters Kluwer Health) ; 2021
    In:  Circulation Vol. 144, No. Suppl_1 ( 2021-11-16)
    Details
    In: Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 144, No. Suppl_1 ( 2021-11-16)
    Abstract: Introduction: Cardiac resynchronization therapy (CRT) is beneficial in patients with heart failure with reduced ejection fraction and normal sinus rhythm. However, its role in patients with pacing indication, narrow QRS, and normal ejection fraction remains controversial. Objectives: We aimed to evaluate the impact of biventricular pacing (BiV) versus conventional right ventricular (RV) pacing (DDD mode, ventricular pacing avoidance algorithm) in patients with normal ejection fraction. Methods: A comprehensive literature search in PubMed, Google Scholar, and Cochrane Review from inception to November 15, 2020, was performed. Outcomes studies were - major adverse cardiovascular events (MACE, composite of cardiovascular death, hospitalization for heart failure or any cardiovascular cause), cardiovascular mortality, change in left ventricular ejection fraction (LVEF, %), left ventricular end-systolic volume (LVESV, mL) and left ventricular end-diastolic volume (LVEDV, mL). Results: Four randomized trials (n=457, BiV group=229, mean age 71.6±4.4 years, RV pacing=228, mean age 70.3±4.38 years) met inclusion criteria. There was a significant reduction in MACE (RR 0.68, 95% CI 0.46-0.99, p=0.04), LVESV [mean difference (MD) -6.42, 95%CI -10.27- -2.57; p=0.001], LVEDV (MD -6.12,95% CI -9.30 to -2.94; p=0.0002) in patients with BiV pacing compared to RV pacing. There was no reduction in cardiovascular mortality and a trend towards improvement in LVEF (MD 3.99,95% -0.12-8.10; p=0.06) with BiV pacing compared to RV pacing during the follow-up period (1.95 years). Conclusion: BiV pacing may be a feasible option for permanent pacing in patients with normal LVEF and may attenuate untoward effects of conventional RV pacing on the left ventricular function.
    Type of Medium: Online Resource
    ISSN: 0009-7322 , 1524-4539
    URL: Article
    DOI: 10.1161/circ.144.suppl_1.10836
    Language: English
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Publication Date: 2021
    detail.hit.zdb_id: 1466401-X
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  • 5
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    Adverse events associated with Aveir TM VR leadless pacemaker: A Food and Drug Administration MAUDE database study
    Wiley ; 2023
    In:  Journal of Cardiovascular Electrophysiology Vol. 34, No. 6 ( 2023-06), p. 1469-1471
    Details
    In: Journal of Cardiovascular Electrophysiology, Wiley, Vol. 34, No. 6 ( 2023-06), p. 1469-1471
    Abstract: Leadless pacemaker (LP) offers an innovative approach for treating bradyarrhythmia, thus avoiding pacemaker pocket and lead‐related complications. The Food and Drug Administration (FDA) has recently approved the Aveir™ leadless pacing system (screw‐in type LP). Methods We queried the FDA MAUDE database to study the safety profile and assess the types of complications with this relatively novel device technology. A MAUDE database search was conducted on January 20, 2023, for reports received post‐FDA approval to capture all adverse events. Results A total of 98 medical device report were reported for Aveir™ LP. After excluding duplicate, programmer‐related, or introducer‐sheath‐related entries ( n  = 34), 64 entries were included. The most commonly encountered problem was high threshold/noncapture (28.1%, 18 events), followed by stretched helix (17.2%, 11 events) and device dislodgement (15.6%, ten events—5 intraprocedural, while 5 in the postoperative Day 1). Other reported events included high impedance (14.1%, nine events), sensing issues (12.5%, eight events), bent/broken helix (7.8%, five events), premature separation (4.7%, three events), interrogation problem (3.1%, two events), low impedance (3.1%, two events), premature battery depletion (1.6%, one event) and inadvertent MRI mode switch (1.6%, one event) and miscellaneous (15.6%, n  = 10). There were eight serious patient injury events—pericardial effusion requiring pericardiocentesis (7.8%, five events) due to cardiac perforation that resulted in two deaths (3.1%) followed by sustained ventricular arrhythmias (4.6%, n  = 3). Conclusion In our study assessing the real‐world safety profile of the Aveir™ LP, serious adverse events have been reported—life‐threatening ventricular arrhythmias, pericardial effusion, device explantation/reimplantation, and death.
    Type of Medium: Online Resource
    ISSN: 1045-3873 , 1540-8167
    URL: Issue
    URL: Article
    DOI: 10.1111/jce.v34.6
    DOI: 10.1111/jce.15932
    Language: English
    Publisher: Wiley
    Publication Date: 2023
    detail.hit.zdb_id: 2037519-0
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  • 6
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    Reappraisal of HER2 Amplification in High-Grade Urothelial Carcinoma Based on 2018 ASCO/CAP Clinical Practice Guidelines
    Oxford University Press (OUP) ; 2021
    In:  American Journal of Clinical Pathology Vol. 156, No. 6 ( 2021-11-08), p. 1130-1141
    Details
    In: American Journal of Clinical Pathology, Oxford University Press (OUP), Vol. 156, No. 6 ( 2021-11-08), p. 1130-1141
    Abstract: To examine and compare human epidermal growth factor receptor 2 (HER2) amplification status in high-grade urothelial carcinoma (HGUCa), using both 2013 and 2018 HER2 reporting guidelines for breast carcinoma from the American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP). Methods HER2 status by fluorescence in situ hybridization (FISH) assay in 78 cases of HGUCa was compared using 2013 and 2018 HER2 reporting guidelines. Results HER2 amplification was observed in 22 (28.2%) of 78 tumors, of which 17 were in group 1, 1 in group 2, and 2 each in groups 3 and 4 (FISH assay, 2018). The remaining 14 HER2-amplified tumors (FISH assay, 2013) became negative, falling into group 2 (FISH assay, 2018) and were either negative or equivocal on immunohistochemistry (IHC, 2018). All FISH-negative tumors (n = 37) using 2013 criteria remained negative (group 5, 2018). FISH-equivocal tumors (2013) were further categorized into HER2 amplified (n = 1) and HER2 negative (n = 4) (2018). Overall, 20 (25.6%) tumors had discordant HER2 FISH results (2018 vs 2013). Conclusions Implementing 2018 guidelines, HER2 amplification decreased from 36 to 22 cases. The group with a HER2/CEP17 ratio of 2 or more and average HER2 copy number less than 4 (group 2) were predominantly negative by IHC, suggesting a biologically distinct group of HGUCa that is different from HER2-amplified tumors, which may not respond to HER2-targeted therapy.
    Type of Medium: Online Resource
    ISSN: 0002-9173 , 1943-7722
    URL: Article
    DOI: 10.1093/ajcp/aqab083
    RVK:
    YV 2000
    RVK:
    XA 18700
    Language: English
    Publisher: Oxford University Press (OUP)
    Publication Date: 2021
    detail.hit.zdb_id: 2039921-2
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  • 7
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    The First CHIME/FRB Fast Radio Burst Catalog
    American Astronomical Society ; 2021
    In:  The Astrophysical Journal Supplement Series Vol. 257, No. 2 ( 2021-12-01), p. 59-
    Details
    In: The Astrophysical Journal Supplement Series, American Astronomical Society, Vol. 257, No. 2 ( 2021-12-01), p. 59-
    Abstract: We present a catalog of 536 fast radio bursts (FRBs) detected by the Canadian Hydrogen Intensity Mapping Experiment Fast Radio Burst (CHIME/FRB) Project between 400 and 800 MHz from 2018 July 25 to 2019 July 1, including 62 bursts from 18 previously reported repeating sources. The catalog represents the first large sample, including bursts from repeaters and nonrepeaters, observed in a single survey with uniform selection effects. This facilitates comparative and absolute studies of the FRB population. We show that repeaters and apparent nonrepeaters have sky locations and dispersion measures (DMs) that are consistent with being drawn from the same distribution. However, bursts from repeating sources differ from apparent nonrepeaters in intrinsic temporal width and spectral bandwidth. Through injection of simulated events into our detection pipeline, we perform an absolute calibration of selection effects to account for systematic biases. We find evidence for a population of FRBs—composing a large fraction of the overall population—with a scattering time at 600 MHz in excess of 10 ms, of which only a small fraction are observed by CHIME/FRB. We infer a power-law index for the cumulative fluence distribution of α = − 1.40 ± 0.11 ( stat. ) − 0.09 + 0.06 ( sys. ) , consistent with the −3/2 expectation for a nonevolving population in Euclidean space. We find that α is steeper for high-DM events and shallower for low-DM events, which is what would be expected when DM is correlated with distance. We infer a sky rate of [ 820 ± 60 ( stat. ) − 200 + 220 ( sys. ) ] / sky / day above a fluence of 5 Jy ms at 600 MHz, with a scattering time at 600 MHz under 10 ms and DM above 100 pc cm −3 .
    Type of Medium: Online Resource
    ISSN: 0067-0049 , 1538-4365
    URL: Article
    DOI: 10.3847/1538-4365/ac33ab
    RVK:
    UA 1000
    Language: Unknown
    Publisher: American Astronomical Society
    Publication Date: 2021
    detail.hit.zdb_id: 2006860-8
    detail.hit.zdb_id: 2207650-5
    SSG: 16,12
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  • 8
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    Prevention and Management of COVID -19
    Valley International ; 2021
    In:  Research and Analysis Journal Vol. 4, No. 11 ( 2021-11-02), p. 01-10
    Details
    In: Research and Analysis Journal, Valley International, Vol. 4, No. 11 ( 2021-11-02), p. 01-10
    Abstract: According to the WHO, total confirmed cases of Coronavirus up to October 07, 2021: 237,091,792 , Deaths: 4,840,927 , and total Recovered case 214,263,057 from COVID-19, triggered by the novel SARS-CoV-2 , the rate of case in major countries USA44,918,565 India33,894,312 Brazil21,517,514 Russia 7,662,560 Italy4,689,341 keeps expanding geographically. SARS-CoV-2 is a 29.9 kb RNA beta-coronavirus that is enveloped, positive-sense, and single-stranded. Close contact with infected patients and exposure to aerosol viruses from medical devices and procedures, such as endoscopy, may put healthcare workers at risk of infection. Current data suggests that children under the age of 18 have a low rate of infection (2.4 present). The current gold standard and confirming test for COVID19 is the detection of viral nucleic acid using reverse transcriptase polymerase chain reaction (RTPCR). The World Health Organization (WHO) has indicated that controlling infectious diseases like COVID19 requires education, isolation, prevention, transmission control, and treatment of sick people. By following the steps one can help to keep the illness from spreading. Protection consists of staying at home (home quarantine) and avoiding direct contact with healthy (potentially asymptomatic) or diseased patient.
    Type of Medium: Online Resource
    ISSN: 2589-9228 , 2589-921X
    URL: Article
    DOI: 10.18535/raj.v4i11.256
    Language: Unknown
    Publisher: Valley International
    Publication Date: 2021
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  • 9
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    Surgical left atrial appendage occlusion in patients with left ventricular assist device
    Wiley ; 2022
    In:  Pacing and Clinical Electrophysiology Vol. 45, No. 4 ( 2022-04), p. 567-570
    Details
    In: Pacing and Clinical Electrophysiology, Wiley, Vol. 45, No. 4 ( 2022-04), p. 567-570
    Abstract: Thromboembolic (TE) events are among the most common and devastating adverse events in patients with continuous‐flow left ventricular assist device (cf‐LVAD). Given the high burden of AF among cf‐LVAD patients, we sought to evaluate the effect of concomitant surgical LAAO in patients receiving cf‐LVAD. Methods A systematic search using electronic databases was performed using the keywords: “left atrial appendage occlusion” and “left ventricular assist device.” Statistical analysis was performed using metapackage for R version 4.0 and Rstudio version 1.2. Mantel–Haenszel risk ratio (RR) random‐effects model was used to summarize data between two groups. The primary outcomes included: (a) stroke; (b) LVAD pump thrombosis; (c) all‐cause mortality Results Three studies with a total of 305 patients (LAAO = 68 and No‐LAAO = 237) were included in the analysis. HeartMate II (39%) and Heartware (27.5%) were the two most common cf‐LVADs utilized, while only 5% received HeartMate III. At a mean follow up of 1.47 years, LAAO group had a lower risk of stroke (8.8% vs. 15.2%, RR 0.64; 95% CI 0.28–1.49), LVAD pump thrombosis (1.5% vs. 3.8%, RR 0.28; 95% CI 0.05–1.55) and all‐cause mortality (5.9% vs. 20.2%, RR 0.69; 95% CI 0.19–2.52) when compared with no‐LAAO group, but the difference did not reach statistical significance. Conclusion Concomitant surgical LAAO at the time of cf‐LVAD implantation demonstrated a trend toward positive outcomes and was not associated with adverse outcomes during the follow‐up period, though the results were not statistically significant
    Type of Medium: Online Resource
    ISSN: 0147-8389 , 1540-8159
    URL: Issue
    URL: Article
    DOI: 10.1111/pace.v45.4
    DOI: 10.1111/pace.14471
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2037547-5
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  • 10
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    D-dimer: A useful marker in neonatal sepsis
    Medknow ; 2015
    In:  Journal of Clinical Neonatology Vol. 4, No. 2 ( 2015), p. 101-
    Details
    In: Journal of Clinical Neonatology, Medknow, Vol. 4, No. 2 ( 2015), p. 101-
    Type of Medium: Online Resource
    ISSN: 2249-4847
    URL: Article
    DOI: 10.4103/2249-4847.154552
    Language: English
    Publisher: Medknow
    Publication Date: 2015
    detail.hit.zdb_id: 2713634-6
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