In:
Circulation, Ovid Technologies (Wolters Kluwer Health), Vol. 141, No. Suppl_1 ( 2020-03-03)
Abstract:
Introduction: Data about race/ethnic differences in functional capacity among U.S. minority groups is limited, although some studies suggest blacks have a shorter six minute walk distance (6MWD), a test of functional capacity. We measured 6MWD in the Multi-Ethnic Study of Atherosclerosis (MESA), and hypothesized that health behaviors, CVD risk factors, prevalent CVD, and pulmonary function may account for any race/ethnic differences observed. Methods: MESA enrolled 6814 adults aged 45-84 years free of clinical CVD during 2000-2002. During the 6 th examination (2016-2018) trained staff measured the distance (in meters) walked by participants who walked laps at their own pace for 6 minutes along a flat and marked 20 meter distance. Race/ethnicity, gender, and education level were ascertained at baseline; Exam 6 values for all other variables were used. Prevalent CVD was defined as having a previously adjudicated event (ischemic heart disease, stroke, or heart failure). The race/ethnicity-6MWD association was evaluated via general linear regression models. We included adjustment for age, sex, education, smoking, alcohol, height, waist circumference, self-reported health status, Kansas City Cardiomyopathy Questionnaire score, diabetes, systolic blood pressure (BP), total cholesterol, BP and cholesterol medication use, creatinine, and prevalent CVD (and FEV1 and FVC for those with spirometry data). Results: A 6MWD was obtained in 2,539 participants (mean age 73 years (range 59-96) 53% female, 41% white, 14% Chinese, 24% Black, and 22% Hispanic; 8% prevalent CVD). The observed 6MWD differed by race/ethnicity by 30-50 m (Table). Covariate adjustment reduced these differences modestly. In the subset (n=2138) with spirometry (Model 4), 6MWD remained different across race/ethnicity. Conclusions: Race/ethnic disparities in functional capacity in this diverse sample are not fully explained by differences in health behaviors, CVD risk factors, prevalent CVD, heart failure symptoms, or pulmonary function.
Type of Medium:
Online Resource
ISSN:
0009-7322
,
1524-4539
DOI:
10.1161/circ.141.suppl_1.P151
Language:
English
Publisher:
Ovid Technologies (Wolters Kluwer Health)
Publication Date:
2020
detail.hit.zdb_id:
1466401-X
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