In:
PLOS ONE, Public Library of Science (PLoS), Vol. 16, No. 10 ( 2021-10-11), p. e0258477-
Abstract:
To demonstrate the large potential of proton minibeam radiotherapy (pMBRT) as a new method to treat tumor diseases, a preclinical proton minibeam radiation facility was designed. It is based on a tandem Van-de-Graaff accelerator providing a 16 MeV proton beam and a 3 GHz linac post-accelerator (designs: AVO-ADAM S.A, Geneva, Switzerland and ENEA, Frascati, Italy). To enhance the transmission of the tandem beam through the post-accelerator by a factor of 3, two drift tube buncher units were designed and constructed: A brazed 5-gap structure (adapted SCDTL tank of the TOP-IMPLART project (ENEA)) and a non-brazed low budget 4-gap structure. Both are made of copper. The performance of the two differently manufactured units was evaluated using a 16 MeV tandem accelerator beam and a Q3D magnetic spectrograph. Both buncher units achieve the required summed voltage amplitude of 42 kV and amplitude stability at a power feed of less than 800 W.
Type of Medium:
Online Resource
ISSN:
1932-6203
DOI:
10.1371/journal.pone.0258477
DOI:
10.1371/journal.pone.0258477.g001
DOI:
10.1371/journal.pone.0258477.g002
DOI:
10.1371/journal.pone.0258477.g003
DOI:
10.1371/journal.pone.0258477.g004
DOI:
10.1371/journal.pone.0258477.g005
DOI:
10.1371/journal.pone.0258477.g006
DOI:
10.1371/journal.pone.0258477.g007
DOI:
10.1371/journal.pone.0258477.g008
DOI:
10.1371/journal.pone.0258477.g009
DOI:
10.1371/journal.pone.0258477.g010
DOI:
10.1371/journal.pone.0258477.g011
DOI:
10.1371/journal.pone.0258477.g012
DOI:
10.1371/journal.pone.0258477.g013
DOI:
10.1371/journal.pone.0258477.g014
DOI:
10.1371/journal.pone.0258477.t001
DOI:
10.1371/journal.pone.0258477.t002
DOI:
10.1371/journal.pone.0258477.s001
Language:
English
Publisher:
Public Library of Science (PLoS)
Publication Date:
2021
detail.hit.zdb_id:
2267670-3
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