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  • 1
    Online Resource
    Online Resource
    Head and Neck Lymphatic Malformation Management Algorithm: An Experience from a Tertiary Centre in Tanzania
    Zambia Medical Association ; 2021
    In:  Medical Journal of Zambia Vol. 48, No. 2 ( 2021-08-10), p. 114-118
    Details
    In: Medical Journal of Zambia, Zambia Medical Association, Vol. 48, No. 2 ( 2021-08-10), p. 114-118
    Abstract: Background: Lymphatic malformations are localized areas of malformed lymphatic system that can either be congenital or acquired which commonly occur in the head and neck region. Several treatment options for lymphatic malformations have been proposed, despite this, there is no consensus as to optimal management. Objective: To determine the pattern and management of head and neck lymphatic malformations in a tertiary health facility in Tanzania. Material and Methods: This was a one-year crosssectional study that involved patients with head and neck lymphatic malformations treated in Muhimbili National Hospital. A structured questionnaire was used to collect information including age and sex ofthe patient, chief complaint and, duration, size and site of the lesion. The treatment modalities were surgery and/or intralesional bleomycin injection (IL-Bleo) using a locally developed algorithm. A standard dose of bleomycin was 0.3 to 0.6 mg/kg per injection not exceeding 15 units per cycle with a maximum of 6 cycles. Results: a total of 33 patients were included in the study. Males were 21 (63.6%) and the male to female ratio was 1.8:1. The age of patients ranged from 5 months to 28 years with a median age of 6 years. In 29 (87.9%) patients, the lesions were evident during birth. The median area covered by the lesion in 2 patients was 12.00 cm . Nine (27.3%) patients were managed by surgery alone, while majority (24, 72.7%) were given intralesional bleomycin (ILBleo), of whom majority (20, 83.3%) required surgical intervention subsequently. The overall outcome of management of patients was considered successful in 87% of patients. Conclusion: Head and neck lymphatic malformations are more common in males. Most of the lymphangiomas are of congenital type. Combining IL-Bleo and surgery an effective way of managing head and neck lymphatic malformations.
    Type of Medium: Online Resource
    ISSN: 0047-651X , 0047-651X
    URL: Article
    DOI: 10.55320/mjz.48.2.876
    Language: Unknown
    Publisher: Zambia Medical Association
    Publication Date: 2021
    detail.hit.zdb_id: 2538342-5
    Location Call Number Limitation Availability
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    Online Resource
  • 2
    Online Resource
    Online Resource
    Predisposing Factors and Clinico-Pathological Presentation of Malignant Lesions Of the Oro-Facial region in Dar es Salaam, Tanzania
    Zambia Medical Association ; 2020
    In:  Medical Journal of Zambia Vol. 46, No. 4 ( 2020-03-19), p. 286-296
    Details
    In: Medical Journal of Zambia, Zambia Medical Association, Vol. 46, No. 4 ( 2020-03-19), p. 286-296
    Abstract: Background: The oro-facial region is made up of a complex anatomical relationship of structures which may be a source of development of malignant lesions. Majority patients who present at the oral and maxillofacial unit of MNH with a variety of malignant lesions are referred cases from upcountry district/regional hospitals and present with advanced stages of disease often with a wide range of complications. Of recent, there has been a dramatic change in the characteristics and demography of some of the common malignant lesions of the oro-facial region. Such changes mightbe attributed to predisposition or systemic changes following exposure to certain external factors. Objective: To determine the predisposing factors and clinico-pathological presentation of malignant lesions of the oro-facial region among patients attending the Muhimbili National Hospital. Methodology: This was a cross-sectional descriptive hospital-based study carried out in the Department of Oral and Maxillofacial Surgery at the Muhimbili National Hospital. A sample of 186 patients with malignant tumours in the oro-facail region attended at MNH during the study period.For every patient, demographic details were recorded and history, clinical examination and laboratory investigations, including biopsy were done. Results: A total of 186 patients, 104 (56.0%) males and 82 (44.0%) females with a ratio of 1.3:1 were included in the study. The age ranged from 3 to 83 years with a mean age of 48.4 ± 19.2 SD years. Thirty-three percent of the patients were aged below 40 years. The commonest reported oral and maxillofacial malignant tumour was SCC with 96 (51.6%) patients followed by KS which had 17 (9.1%) patients and non-specific carcinoma 10 (5.4%) patients. Tobacco use was reported by 89 (47.8%) among whom 62 (69.6%) had used tobacco for more than 20 years. Ninety-six (51.6%) patients reported alcohol use among whom 49 (51.0%) reported to have used alcohol for more than 20 years. Thirty-three (17.7%) patients were HIV positive. All patients with KS were also HIV positive. MEP and PLGA were among very rare tumours occurring in the maxillofacial region that were encountered in this study. Conclusion: There was an increased frequency of malignant tumours in the oral and maxillofacial region among young patients. Tobacco use and HIV infection seemed to have influence on the occurrence of SCC and KS respectively. Majority of patients reported late with advanced disease and over 95% of patients with SCC presented with stages III or IV tumours.
    Type of Medium: Online Resource
    ISSN: 0047-651X , 0047-651X
    URL: Issue
    URL: Article
    DOI: 10.55320/mjz.46.4
    DOI: 10.55320/mjz.46.4.237
    Language: Unknown
    Publisher: Zambia Medical Association
    Publication Date: 2020
    detail.hit.zdb_id: 2538342-5
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 3
    Online Resource
    Online Resource
    Head and Neck Lymphatic Malformation Management Algorithm: An Experience from a Tertiary Centre in Tanzania
    Zambia Medical Association ; 2021
    In:  Medical Journal of Zambia Vol. 48, No. 2 ( 2021-08-13), p. 114-118
    Details
    In: Medical Journal of Zambia, Zambia Medical Association, Vol. 48, No. 2 ( 2021-08-13), p. 114-118
    Abstract: Background: Lymphatic malformations are localized areas of malformed lymphatic system that can either be congenital or acquired which commonly occur in the head and neck region. Several treatment options for lymphatic malformations have been proposed, despite this, there is no consensus as to optimal management.Objective: To determine the pattern and management of head and neck lymphatic malformations in a tertiary health facility in Tanzania.Material and Methods: This was a one-year crosssectional study that involved patients with head and neck lymphatic malformations  treated in Muhimbili National Hospital. A structured questionnaire was used to collect information including age and sex of the patient,  chief complaint and, duration, size and site of the lesion. The treatment modalities were surgery and/or intralesional bleomycin injection (IL-Bleo) using a locally developed algorithm. A standard dose of bleomycin was 0.3 to 0.6 mg/kg per injection not exceeding 15 units per cycle with a maximum of 6 cycles.Results: a total of 33 patients were included in the study. Males were 21 (63.6%) and the male to female ratio was 1.8:1. The age of patients ranged from 5 months to 28 years with a median age of 6 years. In 29 (87.9%) patients, the lesions were evident during birth. The median area covered by the lesion in patients was 12.00 cm2. Nine (27.3%) patients were managed by surgery alone, while majority (24, 72.7%) were given intralesional bleomycin (ILBleo), of whom majority (20, 83.3%) required surgical intervention subsequently. The overall outcome of management of patients was considered successful in 87% of patients.Conclusion: Head and neck lymphatic malformations are more common in males. Most of the lymphangiomas are of congenital type. Combining IL-Bleo and surgery an effective way of managing head and neck lymphatic malformations.
    Type of Medium: Online Resource
    ISSN: 0047-651X , 0047-651X
    URL: Issue
    URL: Article
    DOI: 10.55320/mjz.48.2
    DOI: 10.55320/mjz.48.2.37
    Language: Unknown
    Publisher: Zambia Medical Association
    Publication Date: 2021
    detail.hit.zdb_id: 2538342-5
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
  • 4
    Online Resource
    Online Resource
    Predisposing Factors and Clinico-Pathological Presentation of Malignant Lesions Of the Oro-Facial region in Dar es Salaam, Tanzania
    Zambia Medical Association ; 2019
    In:  Medical Journal of Zambia Vol. 46, No. 4 ( 2019-12-31), p. 286-296
    Details
    In: Medical Journal of Zambia, Zambia Medical Association, Vol. 46, No. 4 ( 2019-12-31), p. 286-296
    Abstract: Background: The oro-facial region is made up of a complex anatomical relationship of structures which may be a source of development of malignant lesions. Majority patients who present at the oral and maxillofacial unit of MNH with a variety of malignant lesions are referred cases from upcountry district/regional hospitals and present with advanced stages of disease often with a wide range of complications. Of recent, there has been a dramatic change in the characteristics and demography of some of the common malignant lesions of the oro-facial region. Such changes mightbe attributed to predisposition or systemic changes following exposure to certain external factors. Objective: To determine the predisposing factors and clinico-pathological presentation of malignant lesions of the oro-facial region among patients attending the Muhimbili National Hospital. Methodology: This was a cross-sectional descriptive hospital-based study carried out in the Department of Oral and Maxillofacial Surgery at the Muhimbili National Hospital. A sample of 186 patients with malignant tumours in the oro-facail region attended at MNH during the study period.For every patient, demographic details were recorded and history, clinical examination and laboratory investigations, including biopsy were done. Results: A total of 186 patients, 104 (56.0%) males and 82 (44.0%) females with a ratio of 1.3:1 were included in the study. The age ranged from 3 to 83 years with a mean age of 48.4 ± 19.2 SD years. Thirty-three percent of the patients were aged below 40 years. The commonest reported oral and maxillofacial malignant tumour was SCC with 96 (51.6%) patients followed by KS which had 17 (9.1%) patients and non-specific carcinoma 10 (5.4%) patients. Tobacco use was reported by 89 (47.8%) among whom 62 (69.6%) had used tobacco for more than 20 years. Ninety-six (51.6%) patients reported alcohol use among whom 49 (51.0%) reported to have used alcohol for more than 20 years. Thirty-three (17.7%) patients were HIV positive. All patients with KS were also HIV positive. MEP and PLGA were among very rare tumours occurring in the maxillofacial region that were encountered in this study. Conclusion: There was an increased frequency of malignant tumours in the oral and maxillofacial region among young patients. Tobacco use and HIV infection seemed to have influence on the occurrence of SCC and KS respectively. Majority of patients reported late with advanced disease and over 95% of patients with SCC presented with stages III or IV tumours.
    Type of Medium: Online Resource
    ISSN: 0047-651X , 0047-651X
    URL: Article
    DOI: 10.55320/mjz.46.4.595
    Language: Unknown
    Publisher: Zambia Medical Association
    Publication Date: 2019
    detail.hit.zdb_id: 2538342-5
    Location Call Number Limitation Availability
    BibTip Others were also interested in ...
    Online Resource
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